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Next Generation Sequencing Based Diagnostic Approaches in Clinical Oncology
Dr. Anton Buzdin (AB) is employed by Omicsway Corp. (USA). AB received grants from Amazon and Microsoft Azure to support cloud computations. Dr. Xinmin Li is director of JCCC Shared Genomics Resource, the University of California, Los Angeles, CA Dr. Ye Wang is Director of Gene testing Department (Core Lab) of Qingdao Central Hospital, the Second Affiliated Hospital of Qingdao University
Handbook of Translational Transcriptomics
Handbook of Translational Transcriptomics: Research, Protocols and Applications provides a comprehensive overview to the field of transcriptomics. With an emphasis on the various protocols and techniques available for investigation, it acts as a practical guide to researchers for implementing their own investigations in the field. The book begins with an overview of the past, present, and potential approaches in the field of transcriptomics, with discussion of choosing the correct approach based on the research needed, it also highlighting the pros and cons of each approach. Following this it explores techniques and protocols for investigating specific approaches focusing on RNA sequencing, ...
Molecular Pathway Analysis Using High-Throughout OMICS Molecular Data
The field molecular pathway analysis evolves rapidly, and many progressive methods have recently been discovered. Molecular Pathway Analysis Using High-Throughout OMICS Data contains the largest collections of molecular pathways. For the first time, guidelines on how to do genomic, epigenetic, transcriptomic, proteomic, and metabolomic data analysis in real-world research practice are given. Molecular Pathway Analysis Using High-Throughout OMICS Molecular Data also focuses on the pathway analysis applications for solving tasks in biotechnology, pharmaceutics, and molecular diagnostics ??It demonstrates how pathway analysis can be applied for the research and treatment of chronic and acute diseases, for next-generation molecular diagnostics, for drug design and preclinical testing; relevant real-world examples, molecular tests, and web resources will be reviewed in-depth.? ??The book shows a tendency of erasing the borders between chemistry, physics, informatics, mathematics, biology, and medicine by means of novel research approaches and instruments, providing a truly multidisciplinary approach.
Genetic Screening and Diagnostics
This report is intended as a primer on the genetic screening and genetic diagnostics industry, aiming to both give proper exposure to investors (with no technical knowledge) and to highlight relevant points to technically-savvy readers. Hence, for the convenience of the particular reader, parts of the report with a deeper technical focus are highlighted and can be skipped by readers focused on a more general view.
Nucleic Acids Hybridization
Several approaches, such as microarray hybridization, have become extremely popular tools for specialists in biochemistry and biomedicine, while the potential of many other advantageous techniques seems to be underestimated. Written by an international team of authors, this book details the current state-of-art in hybridization techniques. Coverage includes experimental protocols along with comprehensive and detailed method descriptions.
Mobile Genetic Elements in Cellular Differentiation, Genome Stability, and Cancer
The human genome, as with the genome of most organisms, is comprised of various types of mobile genetic element derived repeats. Mobile genetic elements that mobilize by an RNA intermediate, include both autonomous and non-autonomous retrotransposons, and mobilize by a “copy and paste” mechanism that relies of the presence of a functional reverse transcriptase activity. The extent to which these different types of elements are actively mobilizing varies among organisms, as revealed with the advent of Next Generation DNA sequencing (NGS). To understand the normal and aberrant mechanisms that impact the mobility of these elements requires a more extensive understanding of how these element...
