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Global collaboration is the cornerstone of scientific advancement. Frontiers in Cardiovascular Medicine have organized a series of special edition Research Topics, with the goal of highlighting the latest advancements in Cardiovascular Medicine across the globe, showcasing the academic excellence and high-quality work of internationally recognized researchers. These collections aim to shed light on the recent progress made across the entire breadth of Cardiovascular Research, and reflect on the challenges faced by researchers across borders.’ This Research Topic focuses on critical health challenges in Africa and major efforts to solve them.
The scientific theme of the book is “Virtualisation – a multifaceted key enabler of Industry 4.0 from holonic to cloud manufacturing” which is addressed in the framework of cyber-physical system development. The book approaches cyber-physical systems for manufacturing with emergent digital technologies: Internet of Things, digital twins (based on the virtualization of production models embedded in the design, virtual commissioning, optimization and resilience of processes and fault tolerance of resources), big data, cloud control and computing, machine learning and cobots, that are applied in the book’s chapters to industry and service sectors such as manufacturing, energy, logistics...
This book is merely a collection of medical cases; it is a tribute to the collaborative efforts of patients, families, caregivers, and researchers in the ongoing quest for cardiovascular health. It serves as a reminder of the importance of empathy, compassion, and human connection in the practice of medicine. As you delve into these clinical vignettes, may you find inspiration, enlightenment, and a renewed sense of purpose in the pursuit of optimal cardiovascular care. May the stories within these pages deepen your understanding, sharpen your clinical acumen, and ignite your passion for improving the lives of those affected by heart disease. Together, let us embark on this journey through the heart, guided by the lessons gleaned from each clinical encounter and empowered by the collective commitment to cardiovascular health.
The chapters in this volume are the Proceedings of the Satellite Symposium of the XVIth World Congress of the International Society for Heart Research on `Signal Transduction in Normal and Diseased Myocardium' which was held in Rotterdam at the Faculty of Medicine & Health Sciences of the Erasmus University, June 30 and July 1, 1995. Diverse and distinct auto-, para-, and endocrine stimuli arriving at the surface of endothelium, smooth muscle cells, cardiomyocytes and fibroblasts within the myocardium, engage cell type-specific receptors, which lead to transmission of signals across the cell plasma membrane and result in the production and activation of second messengers. The most common mec...
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