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This book aims to provide a complete overview of the diagnosis and treatment of gastrointestinal stromal tumors (GISTs). It has been conceived to be both a detailed guide for clinical practice and an updated reference for all those involved in the evaluation of GISTs imaging. The publication provides comprehensive descriptions of the full range of common imaging and non imaging techniques used in the diagnosis and followup of GISTs. Techniques reviewed include: Conventional radiography· Endoscopy and endoscopic ultrasound· Conventional, color-Doppler and contrast-enhanced ultrasound· Computed tomography· Magnetic resonance imaging, and· Contrast-enhanced PET/CT imaging. Both medical and surgical treatment strategies are also fully reviewed. Finally, the book concludes with a chapter that aims to stimulate widespread interest in the formation of new GISTs Units. Written by experts in the field, the book is enriched throughout by numerous black-and-white and color images, making it an invaluable source of information as well as an indispensable guide to interpreting images for radiologists, gastroenterologists, pathologists, oncologists and surgeons.
This book aims to provide readers with a current overview of enrolling trials with immune-checkpoint inhibitors in the preoperative setting of localized bladder cancer, renal cell carcinoma, and prostate cancer. The advent of immunotherapy has revolutionized treatments of genitourinary malignancy and evolved strategies for multidisciplinary management. This book explains neoadjuvant checkpoint inhibitors in localized genitourinary cancers, providing insights into the mechanisms of response and development of resistance of cancer cells to immunotherapy. It debates optimal trial design of preoperative checkpoint inhibitors in GU tumors, including optimal endpoints and the role of pathologic re...
The world is increasingly polarized along religious, ethnic, race, gender, class, and ideological lines. But must such diversity necessarily breed suspicion, fear, or violence? Richard Kearney invites us to consider another path. He wagers that the cause of our divisions often lies not in difference but in a lack of creative imagination. Ever in a spirit of dialogue, he shows how poetics and narrative imagination can break the hold of hostility and open new possibilities of reconciliation, accomplishing what moral arguments alone cannot. Now, more than ever, there is an urgent need for Kearney’s work, which addresses our current moment of crisis and division, providing pathways of creative response and healing. This book follows Kearney’s journey through the fields of philosophy of the imagination, hermeneutics, philosophy of religion, ethics, psychology, practical philosophy, and politics. The selection of writings in this volume offers to the specialist and the general reader a concise, well-rounded entry into one of the most prolific and wide-ranging thinkers in contemporary philosophy.
This volume, through theoretical essays and empirically grounded pieces on Le Corbusier's designs, contemporary suburbs, and the planning agendas of the World Trade Center site, provides theory on the appreciation of site and context in architecture.
The accelerating «iconic turn» in our society today increasingly demands the interactive representation of contextual knowledge. At the same time the use of Web based learning environments highlight the audio-visual dimension of (e)pedagogy and the move towards practical, project-oriented curricula. Regardless of the educational field pedagogical expertise thus requires more and more understanding and control of visual elements and their interpretations. There is a growing need for visually oriented pedagogical experts such as teachers, tutors, designers and developers who are capable of community knowledge building and collaboration with other experts from different fields from both private and public sectors. The book intends to illuminate scientific and programmatic excerpts from an international community of researchers, practitioners, teachers and scholars working in interrelated fields such as Aesthetic Education, ePedagogy Design - Visual Knowledge Building, Visual Education, Art Education, Media Pedagogy and Intermedia Art Education.
In the words of Ezra Talmor: To deal with European Culture in a Changing World is to deal, in fact, with the reciprocal relation between Politics and Economics on the one hand, and Culture on the other. In an era when economic forces are pushing towards European Economic Unity or towards the Globalisation of National Markets it is rather difficult to demarcate the role of Culture. While the European Narrative may have been written by Monnet, De Gaulle, and Adenauer, the Global Narrative is written by an unknown author or rather by Adam Smithâ (TM)s Invisible Hand. On the one hand the postmodernist claim that the Grand Narrative is dead is given the lie. A Grand Narrative is now being writte...