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The history of pharmacology travels together to history of scientific method and the latest frontiers of pharmacology open a new world in the search of drugs. New technologies and continuing progress in the field of pharmacology has also changed radically the way of designing a new drug. In fact, modern drug discovery is based on deep knowledge of the disease and of both cellular and molecular mechanisms involved in its development. The purpose of this book was to give a new idea from the beginning of the pharmacology, starting from pharmacodynamic and reaching the new field of pharmacogenetic and ethnopharmacology.
One of the major shortcomings of the current drug discovery and development process is the inability to bridge the gap between early stage discoveries and pre-clinical research in order to advance innovations beyond the discovery phase. This book examines a drug discovery and development model, where the respective expertise of academia and industry are brought together to take promising discoveries through to proof of concept, providing a means to de-risk the drug discovery and development process.
This book constitutes the refereed post-proceedings of the 10th International Conference and 11th International Conference on Data Management Technologies and Applications, DATA 2021 and DATA 2022, was held virtually due to the COVID-19 crisis on July 6–8, 2021 and in Lisbon, Portugal on July 11-13, 2022. The 11 full papers included in this book were carefully reviewed and selected from 148 submissions. They were organized in topical sections as follows: engineers and practitioners interested on databases, big data, data mining, data management, data security and other aspects of information systems and technology involving advanced applications of data.
Every year nine million people are diagnosed with tuberculosis, every day over 13,400 people are infected with AIDs, and every thirty seconds malaria kills a child. For most of the world, critical medications that treat these deadly diseases are scarce, costly, and growing obsolete, as access to first-line drugs remains out of reach and resistance rates rise. Rather than focusing research and development on creating affordable medicines for these deadly global diseases, pharmaceutical companies instead invest in commercially lucrative products for more affluent customers. Nicole Hassoun argues that everyone has a human right to health and to access to essential medicines, and she proposes th...
"Abstract: Supply chain management contends with structures and processes for delivering goods and services to customers. It addresses the core functions of connected businesses to meet downstream demand. This innovative volume provides an authoritative and timely guide to the overarching issues that are ubiquitous throughout the supply chain. In particular, it addresses emerging issues that are applicable across supply chains-such as data science, financial flows, human capital, internet technologies, risk management, cyber security, and supply networks. With chapters from an international roster of leading scholars in the field, The Oxford Handbook of Supply Chain Management is a necessary resource for all students and researchers of the field as well as for forward-thinking practitioners. Keywords: supply chain management; value; human society; goods and services; competitive advantage; people and welfare; data and technology; moving goods and services; structure and strategy; growing and sustaining"--
In the last several decades, there has been a surge of interest in expertise in the social scientific, philosophical, and legal literatures. While it is tempting to attribute this surge of interest in expertise to the emergence and consolidation of a "knowledge society," "post-industrial society," or "network society," it is more likely that the debates about expertise are symptomatic of significant change and upheaval. As the number of contenders for expert status has increased, as the bases for their claims have become more diverse, and as the struggles between these would-be experts intensified, expertise became problematic and contested. In The Oxford Handbook of Expertise and Democratic...
This timely book explores the innovative non-doctrinal methods currently being used in environmental law research. Drawing on their extensive experience, expert contributors provide insight into how creative approaches to research can improve understanding of law and policy, leading to more effective legal protection for the environment.
Calidad, evaluación, análisis, sitios web? ¿Qué tienen en común todas estas palabras clave para que merezcan la atención del público de esta colección? El punto que lo une todo es la necesidad de un amplio y a la vez muy diverso colectivo profesional de saber qué es lo que hace que un sitio web responda a criterios de calidad. Pongamos el ejemplo de un profesional de la web que recibe el encargo de auditar los sitios web de una empresa de comercio electrónico: quiere estar segura de que está a la altura de sus competidores internacionales; o el de un equipo de investigadores académicos que se pregunta cómo están incorporando las webs de turismo las más recientes posibilidades de interacción debidas a la web 2.0. Lo que tienen en común escenarios y objetivos tan diversos es que, en todos ellos, sus protagonistas necesitarán disponer de alguna herramienta que los ayude a determinar qué necesitan saber en relación con una web determinada o un conjunto de sitios web. Este libro intenta aportar esos instrumentos.