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Biochemistry and Cell Biology of Ageing: Part III Biomedical Science
This book provides a state-of-the-art overview of key areas of subcellular aging research in human cells. The reader is introduced to the historical development and progress in biomedical aging research and learns, for example, about the role of microRNAs, circRNAs, mitochondria and extracellular vesicles in cellular senescence. The reader will also learn more about how gap junctions, the nuclear pore complex and the proteasome are affecting the ageing processes. In addition, novel therapeutic opportunities through modulation of cellular senescence are discussed. The book follows on from Parts I and II of Biochemistry and Cell Biology of Ageing (Volumes 90 and 91 of the Subcellular Biochemistry book series) by covering interesting and significant biomedical ageing topics not included in the earlier volumes. Comprehensive and cutting-edge, this book is a valuable resource for experienced researchers and early career scientist alike, who are interested in learning more about the fascinating and challenging question of why and how our cells age.
Appearance and Identity Crisis in Modern Indian History
Chakarawarti explores the history of Indian eunuchs from the Mughal empire’s fall following the mutiny of 1857 A.D. to the Supreme Court of India’s historic ruling in 2014 A.D. This book examines the social, political, economic, and religious aspects of Indian eunuchs’ lives, providing a true narrative of this marginalized group that has been neglected for centuries. It contains detailed stories of Indian eunuchs from the 1857 uprising to the historic decision to grant them the title of third gender in the Supreme Court of India in 2014. This includes the actual account of the court proceedings and how this decision brought about an enormous transition to their lives by granting them fundamental rights under the Constitution of India and the right to self-identification of their gender as male, female, or third gender. This book serves as an important resource for scholars of Gender Studies, Transgender Studies, and Subaltern History, and especially for those who are interested in Transgender Studies in modern Indian history.
Civil Resistance Against 21st Century Authoritarianism. Defending Human Rights in the Global South
Populist authoritarian governments have jeopardized the human rights accomplishments of the 20th century. Ensuring their fulfillment has become a challenge for these governments and an issue for human rights defenders seeking to find ways to resist anti-democratic actions. This book seeks to expose the crisis of human rights at the hands of people who, despite rising to power through democratic means, now see democracy as a limiting institution that must be dismantled urgently. Restrictions on civil society and arbitrary detentions are some of the reasons why this populist and authoritarian vision is incompatible with human rights, which are guaranteed to some and denied to others. Through various narratives, the authors seek to recognize new spaces for struggle—such as political activism—to develop action-research tools in a context of crisis.
How People Respond to Violence
This book explores the powerful role of ordinary people's agency in times of violent conflict. Drawing on extensive fieldwork and a Critical Discourse Analysis, the author draws out the motivations, drivers and strategies at individual and community levels. With a focus on people’s own voices, this research highlights rich findings showing a wide range of experiences and actions that people engaged in during the violent conflict, and dimensions that are often missed in dominant explanations of violent conflict. Therefore, while looking at peace and conflict from an everyday perspective, the question of power and the meaning of peace knowledge become central. This monograph addresses the power of people’s agency not only in shaping the politics and dynamics of violence, but also in redefining what ‘peace’ and ‘change’ ought to look like. Essential reading for researchers and students of Peace and Conflict Studies, and also International Relations, Security Studies, Resistance Studies, Anthropology, Politics, International Development.
The Absent State
The spiralling crisis in Jammu and Kashmir; the Naxalite-Maoist menace that seems to be intensifying with every passing day; the disturbing reach of proxy governments run by militant groups in Manipur and Nagaland – today, a quarter of India is being held hostage by violence and anarchy. What has pushed the country, which has otherwise held together through seemingly insurmountable odds in the past, to the edge? Who and what is responsible for the state of affairs as it stands today? In a series of dispatches from the epicentres of what they call the country’s ‘battle zones’, Neelesh Misra and Rahul Pandita unveil the tensions, frustrations and heartbreaks, and the challenges and jus...
South Asia's Nuclear Security
South Asia is often viewed as a potential nuclear flashpoint and a probable source of nuclear terrorism. But, how valid are such perceptions? This book seeks to address this question and assesses the region’s nuclear security from two principal standpoints. First, it evaluates the robustness of the Indo-Pakistani mutual deterrence by analysing the strength and weaknesses of the competing arguments regarding the issue. It also analyses the causes and consequences of nuclear arms race between India and Pakistan, the nature of deterrence structure in the region and the challenges of confidence building and arms control between the two countries in order to assess the robustness of South Asiaâ...
Claiming India from Below
Going beyond electoral politics and government, this volume broadens the scope of the functioning of democracy in India, and explores citizens’ role in the implementation of public policy. It looks at the ways in which extra-parliamentary power monitoring devices such as public institutions, citizens’ associations or assemblies, and the mainstream and emerging forms of the media, permeate through the political order. The volume: • brings participation and communication in governance and policy making to the centrestage; • examines case studies of state and citizen engagement from across India; and • presents perspectives of practitioners, activists and scholars to provide a comprehensive view of the debates surrounding the idea of Indian democracy. This book will be useful to scholars and researchers in politics, political science, media studies, public administration, sociology and social anthropology, as well as the interested general reader.
Skin 3-D Models and Cosmetics Toxicity
Efforts are being made by research organizations and cosmetic industries worldwide to develop more precise and targeted 3D models that mimic humans for testing cosmetic and personal health care product ingredients, following a complete ban on animal testing. This book includes several subtopics dedicated to the progress made, challenges faced, roadblocks encountered, and future prospects in the development and validation of 3D models for testing these products. The book consist of an editorial and 14 themed chapters that will showcase the significant progress made so far, challenges encountered, and future prospects in the development of 3D reconstruct models.
Proceedings of the Sixth International Conference on Mathematics and Computing
This book features selected papers from the 6th International Conference on Mathematics and Computing (ICMC 2020), organized by Sikkim University, Gangtok, Sikkim, India, during September 2020. It covers recent advances in the field of mathematics, statistics, and scientific computing. The book presents innovative work by leading academics, researchers, and experts from industry.
