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Proceedings of the First Joint NASA Cardiopulmonary Workshop
On 5-7 December 1990, a workshop was held at the Johnson Space Center to promote communication and cross fertilization of ideas among NASA cardiopulmonary principal investigators. This was the first such meeting of cardiopulmonary investigators sponsored by the Johnson Space Center, Kennedy Space Center, and the Ames Research Center. Each principal investigator gave a 20-minute summary of recent progress in his or her laboratory. Topics covered included flight echocardiography (J. Charles), pulmonary function (H. Guy), central hemodynamics (R. Latham), glycerol hyperhydration (M. Riedesel), spectral analysis (C. Knapp and A. Goldberger), lower body negative pressure countermeasures (S. Fortney), orthostatic tolerancy (J. Buckey), autonomic function (V. Convertino, M. Smith, D. Eckberg), cardiac deconditioning (C. Tipton), fluid and renal responses to head-down tilt (B. Tucker), local fluid regulation (A. Hargens), endocrine regulation during bedrest (J. Vernikos, C. Wade), autogenic feedback (P. Cowings), and chronic cardiovascular measurements (S. Vatner). The program ended with a general discussion of weightless models and countermeasures. Publisher.
Adaptation Biology and Medicine
Recognition of adaptive processes in biological systems as a discipline is still in its infancy. It is known that repeat exposure to low level stresses such as heat, cold, microgravity, hypoxia, exercise, etc. increases body-resistance to not only the particular stress but also to other conditions. Such a cross-protection can be utilized in a better patient care. This volume describes most current developments in the understanding of the molecular basis of adaptation as well as its application in biological systems including certain disease conditions in humans. The book is based on the presentations made by internationally known experts assembled in San Diego, USA for the 7th World Congress of the International Society for Adaptive Medicine and will be of great interest to experimental biologists as well as clinicians who deal with a wide variety of clinical conditions.
Physiological Adaptations in Vertebrates
This volume originates from a symposium held in Copenhagen in June 1989 to commemorate Kjell Johansen, who died March 4, 1987. The volume begins with a nonscientific but fascinating glimpse at Kjell, followed by an overview of the kinds of physiology that interested him, i.e. adaptational, environme
Tissue Nutrition and Viability
Recent research, especially in fields of orthopaedic surgery and rehabilita tion, point to the importance of periodic, moderate stress for maintaining normal structure and function of tissues. Moreover, growth and healing of load-bearing tissues such as bone, cartilage, and intervertebral disc are especially dependent upon stress-related stimuli. Extreme levels of stress, however, are usually detrimental to tissue integrity, and most treatment regimens today address problems related to trauma and other conditions of abnormally high stress. Therefore, the purpose of this book is to bring together experts in fields of tissue nutrition and growth in order to review previous work and examine new...
Adaptation Biology and Medicine. Volume 7
It has become amply clear that all live forms on Earth are the products of the constituent genes expressed under the influence of continuously changing natural environment. By the same token, gene expression is known to be modified by our (or by the modern) environment inclusive of factors such as gravity, altitude, temperature, atmospheric pressure and air quality, physical conditioning as well as nutrition and/or lifestyle. Life would not survive without recruiting endogenous adaptive mechanisms responsive to challenging environmnetal factors, Biology of adaptation as well as application of this knowledge has been discussed in both health and disease conditions such as cardiac ischemia and cardiomyopathies, stroke, dementia, Alzheimer's, cancer, metal toxicity, etc. The book will be of great interest to experimental biologists and health professionals dealing with benefits and failures of physiological and pathophysiological adaptations. It will also serve as an important source of information for young scientists, postdocs and students.
Intracranial Pressure And Its Effect On Vision In Space And On Earth: Vision Impairment In Space
Fluid distribution during spaceflight and impact on brain and vision health is an emerging field of high-priority research in the NASA human space program. International Space Station astronauts have developed ocular refraction changes during prolonged spaceflight. Within this book, experts review current data related to fluid shifts during microgravity exposure and the impact of fluid shifts on astronaut health. This work also compares current astronaut health problems with Earth-based health conditions such as elevated intracranial pressure and glaucoma. Chapters include discussion of altered fluid distribution, including intracellular and extracellular fluid shifts, eye morphology and vision disturbances, and intraocular pressure. In addition, chapters will include a discussion of advanced non-invasive technologies to investigate the abovementioned fluid volume and pressure variables. As such, the book aims to bridge health professionals, researchers, and science professionals by a presentation of ophthalmology topics critical to future human space exploration, thus providing new perspectives to solve emerging brain and eye disease on Earth and in Space.
Fatigue
This volume describes the current state of our knowledge on the neurobiology of muscle fatigue, with consideration also given to selected integrative cardiorespiratory mechanisms. Our charge to the authors of the various chapters was twofold: to provide a systematic review of the topic that could serve as a balanced reference text for practicing health-care professionals, teaching faculty, and pre-and postdoctoral trainees in the biomedi cal sciences; and to stimulate further experimental and theoretical work on neurobiology. Key issues are addressed in nine interrelated areas: fatigue of single muscle fibers, fatigue at the neuromuscular junction, fatigue of single motor units, metabolic fatigue studied with nuclear magnetic resonance, fatigue of the segmental motor system, fatigue involving suprasegmental mechanisms, the task dependency of fatigue mechanisms, integrative (largely cardiorespiratory) systems issues, and fatigue of adapted systems (due to aging, under-and overuse, and pathophysiology). The product is a volume that provides compre of processes that operate from the forebrain to the contractile proteins.
Recapturing a Future for Space Exploration
More than four decades have passed since a human first set foot on the Moon. Great strides have been made in our understanding of what is required to support an enduring human presence in space, as evidenced by progressively more advanced orbiting human outposts, culminating in the current International Space Station (ISS). However, of the more than 500 humans who have so far ventured into space, most have gone only as far as near-Earth orbit, and none have traveled beyond the orbit of the Moon. Achieving humans' further progress into the solar system had proved far more difficult than imagined in the heady days of the Apollo missions, but the potential rewards remain substantial. During its...
Biomedical Engineering Fundamentals
Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.Biomedical Engineering Fundamentals, the first volume of
Biomechanics
Presents Current Principles and ApplicationsBiomedical engineering is considered to be the most expansive of all the engineering sciences. Its function involves the direct combination of core engineering sciences as well as knowledge of nonengineering disciplines such as biology and medicine. Drawing on material from the biomechanics section of The
