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Sjögren’s Syndrome: Pathogenicity, Novel targets and Antigens.
Dr. Baer is the site PI for a clinical trial investigating treatments related to Sjogren’s Syndrome, in conjunction with Viela Bio. The other Topic Editors declare no competing interests with relation to the topic theme.
Dry Mouth, The Malevolent Symptom
Xerostomia, more commonly called dry mouth, affects an estimated 20 percent of adults worldwide and can severely diminish one’s quality of life. Dry Mouth, the Malevolent Symptom: A Clinical Guide relies on evidence-based research to provide an introductory primer on oral dryness and the modalities available to treat it. The book describes the varied etiology of the disease, but emphasizes clinical protocols and step-by-step procedures for diagnosis and treatment planning. Dry Mouth is a user-friendly manual guiding clinicians through identifying and managing this common condition. Causes including radiotherapy, chemotherapy, systemic diseases, polypharmacy, and the natural progression of aging are discussed in conjunction with the clinical symptoms and signs associated with each one. Multiple avenues for treatment are presented, highlighting salivary stimulation and supplementation techniques, pharmacologic aids, and critically required oral therapy. Although intended primarily for the professionals that treat those affected by xerostomia, Dry Mouth may also be of interest to sufferers of this condition.
Salivary Diagnostics
Salivary Diagnostics surveys one of the most exciting areas of research in oral biology. Regarded as the mirror of the body, saliva has immense potential to yield real clinical improvements in our ability to diagnose, and hence treat, oral and systemic conditions. The composition of saliva and other oral fluids reflects the tissue fluid levels of therapeutic, hormonal, and immunological molecules, as well as the presence of markers for systemic and oral disease.
Dry Mouth, The Malevolent Symptom
Xerostomia, more commonly called dry mouth, affects an estimated 20 percent of adults worldwide and can severely diminish one’s quality of life. Dry Mouth, the Malevolent Symptom: A Clinical Guide relies on evidence-based research to provide an introductory primer on oral dryness and the modalities available to treat it. The book describes the varied etiology of the disease, but emphasizes clinical protocols and step-by-step procedures for diagnosis and treatment planning. Dry Mouth is a user-friendly manual guiding clinicians through identifying and managing this common condition. Causes including radiotherapy, chemotherapy, systemic diseases, polypharmacy, and the natural progression of aging are discussed in conjunction with the clinical symptoms and signs associated with each one. Multiple avenues for treatment are presented, highlighting salivary stimulation and supplementation techniques, pharmacologic aids, and critically required oral therapy. Although intended primarily for the professionals that treat those affected by xerostomia, Dry Mouth may also be of interest to sufferers of this condition.
Clinical Textbook of Dental Hygiene and Therapy
Fully revised and updated to reflect changes in clinical practice, legislation and regulation, this groundbreaking textbook intertwines the subjects of dental hygiene and dental therapy to provide a comprehensive resource for students of these courses, as well as those studying new degree programmes in oral health science. The Clinical Textbook of Dental Hygiene and Therapy is designed as a dedicated companion text for these disciplines and should enable students to streamline their primary reading. Following course developments and an expansion in the remits of both hygienists and therapists, this book is written not only for students, but also as a revision aid for those already in practic...
The MASCC Textbook of Cancer Supportive Care and Survivorship
Addressing physical and psychosocial matters of survivorship prior to, during, and after anticancer treatment is central to a patient’s wellbeing. The MASCC Textbook of Cancer Supportive Care and Survivorship explores not only the diagnosis and treatment but also the increasingly recognized complex and ongoing symptoms experienced by long term cancer survivors. Significant advances have been made, designing strategies to manage the side effects and symptoms of treatment and to prevent them from occurring, maximizing the person’s ability to pursue daily activities. The MASCC Textbook of Cancer Supportive Care and Survivorship assembles international, multidisciplinary experts who focus on a comprehensive range of symptoms and side effects associated with cancer and its treatment. Intended for health professionals involved with cancer care, medical oncologists, radiation oncologists, surgeons, general practitioners, nurses and allied health workers, this textbook provides current information on the management and prevention of cancer related side effects, referring to up-to-date sources that are useful for conducting further research.
Diseases of the Salivary Glands
A large number of diseases affect salivary gland (SG) secretion through different mechanisms, leading to SG dysfunction and associated oral problems. The glands may suffer from viral, bacterial, and, albeit rarely, fungal infections, which may cause painful swelling or obstruction; they could also become the target of an autoimmune attack or may be affected by various benign and malignant tumors which consist of a heterogeneous group of lesions with complex clinical–pathological characteristics. The loss of normal SG function results in widespread deterioration of oral health. This book, entitled “Diseases of Salivary Glands”, provides an overview of recent advances in the field of SG disorders, focusing on the cellular and molecular mechanisms involved in the pathogenesis of SG diseases and on the most innovative investigation techniques that could help to preserve patients’ health, function, and quality of life.
Saliva: Secretion and Functions
Health professionals are more and more aware of the importance of saliva for oral health and well-being. As saliva secretion is steadily compromised with advancing age, it becomes a factor of concern in societies with an aging population, especially with a growing number of people who keep their own teeth. The numerous functions of saliva, like antimicrobial activity, lubrication, wound healing and its role in taste experience are only truly recognized when saliva secretion is hampered. In medical diagnostics, saliva shows its value as a safe and economical alternative to blood. This publication provides a comprehensive overview of the latest developments in salivary research by some of the world’s leading experts in the field. Chapters deal with various aspects: anatomy and physiology, e.g. regeneration of salivary glands, saliva functions, e.g. its protective and rheological properties, and diagnostics and disorders, e.g. xerostomia and hypersalivation. This book is not only recommended to basic scientists working in the field of oral biology, but also to dental students, dentists and health professionals who want to know more about one of the most underestimated bodily fluids.
Sjögren’s Syndrome
Sjögren’s Syndrome: Diagnosis and Therapeutics provides a thorough, multisystemic overview of the clinical manifestations of Sjögren’s Syndrome. It contains chapters pertinent across the range of medical specialties that may encounter Sjögren’s Syndrome cases. Chapters are specialty-specific, for easy reference by the relevant medical specialist. In addition to being a diagnostic guide, Sjögren’s Syndrome: Diagnosis and Therapeutics includes a section on prognosis and outcomes of Sjögren’s Syndrome patients and provides an exhaustive therapeutic update, focused on new agents and experimental techniques. The inclusion of diagnostic/therapeutic algorithms illustrates the text with clinical photographs of the main organs involved and helps the reader to make guided diagnostic and therapeutic decisions through decision-based algorithms.
Sjogren’s Disease, An Issue of Rheumatic Disease Clinics of North America, E-Book
This issue of Rheumatic Disease Clinics is devoted to Sjogren's Disease. The articles will include everything from the Use of Biologics, Autoantibodies, and Genetics, to Proteomics of Saliva/Tears, Parotid Biopsy, Use of Ultrasound, and many more!
