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Epigenetic Epidemiology
The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored. This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laborato...
GIS for Group Decision Making
In today's society, it is very common for decisions that influence us all to be made by a combination of interested parties, all with their own agenda. In this instance, how can we be sure that the decision is the correct one, not just decided by the group with the most political influence or most money? Such groups have now become fundamental deci
Studies in Stomatology and Craniofacial Biology
Studies in Stomatology and Craniofacial Biology contains 33 papers under the general headings of developmental biology, developmental pathology, acquired pathology, and gene therapy. The book covers the basic science of stomatology (diseases of the mouth) and craniofacial biology in general. The subject matter is wide in scope and utilizes a variety of modern molecular and genetic approaches. Major topics are covered such as: Developmental Biology; Developmental Pathology; Acquired Pathology; Gene Therapy. This book will be of great interest to researchers in genetics, embryology, bone biology, dental science, microbiology and oncology.
Handbook of Anxiety and Fear
This Handbook brings together and integrates comprehensively the core approaches to fear and anxiety. Its four sections: Animal models; neural systems; pharmacology; and clinical approaches, provide a range of perspectives that interact to produce new light on these important and sometimes dysfunctional emotions. Fear and anxiety are analyzed as patterns that have evolved on the basis of their adaptive functioning in response to threat. These patterns are stringently selected, providing a close fit with environmental situations and events; they are highly conservative across mammalian species, producing important similarities, along with some systematic differences, in their human expression...
Fourteenth International Conference Zaragoza–Pau on Mathematics and its Applications
The International Conference Zaragoza-Pau on Mathematics and its Applications was organized by the Departamento de Matemática Aplicada, the Departamento de Métodos Estadísticos and the Departamento de Matemáticas, all of them from the Universidad de Zaragoza (Spain), and the Laboratoire de Mathématiques et de leurs Applications, from the Université de Pau et des Pays de l’Adour (France). This conference has been held every two years since 1989. The aim of this conference is to present recent advances in Applied Mathematics, Statistics and Pure Mathematics, putting special emphasis on subjects linked to petroleum engineering and environmental problems. The Fourteenth Conference took place in Jaca (Spain) from 12nd to 15th September 2016. During those four days, 99 mathematicians, coming from di erent universities, research institutes or the industrial sector, attended 14 plenary lectures, 62 contributed talks and a poster session with 4 posters. We note that in this edition there were 11 mini-symposia, two of them co-organized by colleagues from the Universidad de Zaragoza and the Université de Pau et des Pays de l’Adour.
The Biology and Pathology of Innate Immunity Mechanisms
In recent years increased scientific attention has been given to immediate defense mechanisms based on non-clonal recognition of microbial components. These mechanisms constitute the innate immunity arm of the body s defense. Identification of pathogens by these mechanisms involves primarily receptors recognizing sugar moieties of various microorganisms. Innate immunity based mechanisms are essential for the existence of multicellular organisms. They are evolutionarily conserved and designed to provide immediate protection against microbial pathogens to eradicate infection. Activation of innate immunity is crucial for transition to specific immunity and for its orientation, and to assist the...
