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Viruses
Viruses encapsulates for the lay reader the enormous scientific and medical contributions that have come from the field of virology. Dr. Arnold Levine presents the story of the scientists behind our current understanding of these infective agents and explains how that knowledge has helped us comprehend life at both the molecular and the human level. Many intriguing facets of viral behavior are explored, as Dr. Levine provides a clear account of their natural history, the mechanisms by which they spread and survive, and the toll they exact on their animal, plant, and bacterial hosts. Dr. Levine celebrates the great successes that have come from viral studies--the development of a wide range o...
The P53 Protein
Decades of research on the tumor suppressor p53 have revealed that it plays a significant role as a "guardian of the genome," protecting cells against genotoxic stress. In recent years, p53 research has begun to move into the clinic in attempts to understand how p53 is frequently inactivated in-and sometimes even promotes-human cancer. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine covers the rapid progress that has recently been made in basic and clinical research on p53. The contributors review new observations about its basic biology, providing updates on the functions of its isoforms and domains, the myriad stresses and signal...
The P53 Family
This volume offers a comprehensive review of the functions of the p53 family. The contributors examine the normal roles of these transcription factors, their evolution, the regulatory mechanisms that control p53 activity, and the part played by p53 mutations in tumorigenesis.
Political Corruption
Are phenomena labeled as corrupt subject to systematic social science investigation, or does corruption lie so much in the eye of the beholder as to frustrate serious analysis? The editors of this volume, which follows up an important earlier work on the same subject, hold that the comparative perspective, involving both comparisons over time and comparisons between systems, is crucial if the study of corruption is to reach the point where it can be studied as s socio-political phenomenon. The studies of political corruption included here pertain to all areas of the world, but especially to the United States, Communist systems and Europe. Most were published during the last fifteen years, an...
Current Catalog
First multi-year cumulation covers six years: 1965-70.
