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This timely book discusses antimicrobial drug resistance, specifically, the resistance against the beta-lactam class of antibiotics by Gram-Negative bacteria. The book is broadly divided into five sections. The first section describes the underlying mechanisms of antimicrobial resistance in Gram-negative bacteria. It gives an insight into the beta-lactamases, their types, classification, inhibitors, etc. The second section delves deep into the genetic basis of resistance. It talks about transposons, integrons, insertion sequences associated with antibiotic-resistant genes. The next section describes phenotypic and molecular methods to detect beta-lactam resistance. The fourth section talks about the epidemiology and prevalence of beta-lactamases in the environment. The last section of the book describes the various therapeutic options to combat this growing public threat of antimicrobial resistance. It talks about the current reserve drugs, as well as the newer antibiotic agents that are in the pipeline. This book is essential for clinical practitioners, students, and researchers in basic and medical microbiology.
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**Selected for Doody's Core TitlesĀ® 2024 in Microbiology**Understanding Microbial Biofilms: Fundamentals to Applications focuses on the microbial biofilms of different environments. The book provides a comprehensive overview of the fundamental aspects of microbial biofilms, their existence in nature, their significance, and the different clinical and environmental problems associated with them. The book covers both the fundamentals and applications of microbial biofilms, with chapters on the introduction to the microbial community and its architecture, physiology, mechanisms and imaging of biofilms in nature and fungal, algal, and bacillus biofilm control. In addition, the book highlights t...
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Biosurfactants and bioemulsifiers are considered green molecules as they are produced from microbes and are easily degradable as compared to surfactants. They are suitable due to properties such as low toxicity, tolerance to a wide-range pH level and temperature, high surface activity, biodegradability, excellent emulsifying and demulsifying ability. While, caution and care should be exercised in its widespread usage, they are likely to replace chemical surfactants. The book focuses on biosurfactant production from various bacteria, diversity of biosurfactant producing bacteria, and the industrial need of biosurfactants. Fields such as pharmacy, medicine, and cosmetics are covered. It is presented in an easy-to-understand manner, and is well illustrated, and comprises protocols and recent data on the production, formulation and commercialization and other aspects of biosurfactants and bioemulsifiers.
This book will cover recent and advanced concepts in nanobiotechnology, with deep focus on their applications and commercialization. Expanding Nanobiotechnology: Applications and Commercialization covers topics like green synthesis, microbial synthesis and their applications in medicine, imaging and nanotheranostics. It also includes success stories in food, energy and environment. The book explains the mechanistic insights in the biological synthesis of nanoparticles and includes discussion on the toxicity and interaction with the natural systems in detail. The chapters also examine synthesis and fabrication aspects in a concise manner. The book also highlights the possible therapeutic and ...
A digital twin represents the indistinguishable digital counterpart of the physical object to simulate, monitor and test with real time synchronization. This book presents the framework and important key aspects of digital twins, including various technologies with coverage of the digital twins in various industry and business applications. It provides a background of modeling and simulation, computer sensor technology and other areas required creating the next wave of digital twins. Features: Presents exclusive material on industrial and business applications of digital twins Includes diversified digital twin applications with use cases Focuses on tools and methods for digital twins, platforms, application domains and industries Emphasizes advances and cutting-edge technologies throughout Reviews artificial intelligence (AI), fog/edge computing, industrial automation, blockchains and the Internet of Things (IoT) This book is aimed at researchers and graduate students in cloud computing, simulation, the IoT and computer engineering.