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Diabetes and Cardiovascular Disease
Diabetes and cardiovascular disease together account for the largest portion of health care spending compared to all other diseases in Western society. This work seeks to provide an understanding of the causes of diabetes and its cardiovascular complications. As this understanding becomes more widely appreciated, it will serve as a foundation for evidence-based care and wider acceptance of sound science. The International Conference on Diabetes and Cardiovascular Disease, held in Winnipeg, in June 1999, was organized to bring together a multi-disciplinary group of researchers dedicated to further knowledge amongst researchers, care givers, and the managers of the health system. The invited speakers submitted their works for publication, which serves as the basis for this book. Major themes include: epidemiology of diabetes mellitus, metabolic risk factors in diabetes and cardiovascular disease, hypertension in diabetes mellitus, cardiac function in diabetes, glycemic control and improved cardiovascular function, diabetes management, and endothelial function in diabetes.
Mycotoxins and Food Safety
Mycotoxins, from the Greek "mukes" referring to fungi or slime molds and toxin from the Latin "toxicum" referencing a poison for arrows, have earned their reputation for being potentially deleterious to the health and well being of a consuming organism, whether it be animal or human. Unfortunately, mycotoxins are a ubiquitous factor in the natural life cycle of food producing plants. As such, control of the potential impact of mycotoxins on food safety relies heavily upon accurate analysis and surveys followed by commodity segregation and restricted use or decontamination through processing. The purpose of this book is to provide the most comprehensive and current information on the topic of mycotoxins and assuring food safety. Chapters represented in the book reflect such diverse topics ranging from occurrence and impact, analysis, reduction through processing and plant breeding, toxicology and safety assessments to regulatory perspectives. Authors represent a range of international perspectives.
Partnership for Excellence
The University of Toronto’s Faculty of Medicine is North America’s largest medical school and a major health consortium, boasting nine affiliated teaching hospitals and a network of research institutes. It is where insulin was pioneered, stem cells were first discovered, and famous physicians from Vincent Lam to Sheela Basrur began their careers. But despite all its major accomplishments, the faculty’s impressive history has never before been comprehensively documented. In Partnership for Excellence, senior medical historian and award-winning author Edward Shorter details the Faculty of Medicine’s history from its inception as a small provincial school to its present day status as an international powerhouse. Deeply researched through front-line interviews and primary sources, it ties the story of the faculty and its teaching hospitals to the general history of medicine over this period. Shorter emphasizes the enormous concentration of intellectual energy in the faculty that has allowed it to become the dominant force in Canadian medicine, home to a legion of medical pioneers and achievements.
Published Scientific Papers of the National Institutes of Health
Each issue lists papers published during the preceding year.
The Endocrine System
The endocrine system, comprised of a number of hormone-secreting glands, is vital to the functioning of the human body. In addition to its role in reproductive activity, the endocrine system regulates tissue growth, responses to injury and stress, and helps maintain necessary levels of chemicals throughout the body. This detailed volume carefully examines the major glands of the endocrine system as well as the consequences of its dysfunction and disorder.
Essential Nutrients in Carcinogenesis
For more than 50 years, it has been recognized that diet influences cancer formation both in humans and in experimental animals. In fact, early investigators successfully retarded the onset of tumors in animals by dietary manipulation. Such findings led to an early optimism that cancer would prove to be yet another disease resulting from dietary imbalances and might thus be amenable to prevention or cure by appropriate nutritional changes. Subsequent studies showed that the influence of diet on cancer formation was not only very complex, it also did not appear to playa direct causative role in carcinogenesis. Thus during the mid-1950s scientific interest in diet and cancer greatly waned. By ...
Bioactive Components of Human Milk
The major emphasis in this book is a compilation and definition of what is known about components of human milk, including glycoconjugates, that inhibit common pathogens of the infant. Also discussed are other bioactive constituents whose relevant biological roles are also beginning to be defined. Hormonal and cytokine activity, immunomodulating and autoinflammatory agents, xenobiotics, and conditionally essential nutrients in milk could have roles in the protection of the infant, but may also participate in digestive processes, maternal-infant communication, maturation of the gut, central nervous system, and other components of infant growth and development. Like the protective activities, these are discussed in terms of their presence in milk, structures, potential functions, and structure/function relationship. Components whose role is nutritional support during early development of the infant are also included.
Intractable Seizures
About 20% of people with epilepsy have seizures which are resistant to anticonvulsant medications. These drug-resistant seizures are called `intractable', and the patients who have them - about 1 in 500 of the general population - present a major challenge to neurologists and epilepsy associations. The present volume describes the symptomatology of the major `intractable' syndromes, the most appropriate drugs for each, and the possibilities for surgical control. Research related to the causes and effects of unchecked seizures is presented, and new directions in prevention and therapy are discussed.
Oxygen Transport to Tissue VIII
In this volume the policy of review by anonymous referees and minor correction by the editor has been continued, but perhaps should not be extended without an agreed policy statement by the Society. Our choice is minimal revision with rapid publication or proper review with some delay in publication. The editor wishes to express his gratitude to Ann Richardson, Joann Fish, Lance Johnson, and Philip Weinbrecht for their invaluable help in the preparation of this volume. Ian S. Longmuir v BRIEF HISTORY OF ISOTT The Society endured a long gestation period. During the 1960s its formation was discussed at a number of international meetings devoted to oxygen in biological systems. Prominent among ...
