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A concise assessment of the risks to human health and the environment posed by exposure to benzoic acid and sodium benzoate. Benzoic acid is used as an intermediate in the synthesis of several compounds, including phenol and caprolactam. The compound is increasingly used in the production of diethylene and dipropylene glycol dibenzoate plasticizers in adhesive formulations, and to improve the properties of alkyd resins for paints and coatings. Most releases of benzoic acid and sodium benzoate into the environment result from their use as preservatives in food, beverages, mouthwashes, dentifrices, and cosmetics. For sodium benzoate, the largest use is as an anticorrosive added to antifreeze c...
A comprehensive overview of techniques and systems currently utilized in predictive toxicology, this reference presents an in-depth survey of strategies, algorithms, and prediction methods to select, calculate, and represent the features and properties of chemical structures in biological systems. It provides sources of high-quality toxicity data, the most important commercial and noncommercial predictive toxicology programs, and advanced technologies in computational chemistry, biology, statistics, and data mining. Predictive Toxicology explores applications that go beyond classical structure-activity relationships and discusses programs such as OncoLogic, META, MC4PC, PASS, and lazar.
Integrates data obtained from a variety of disciplines to evaluate the current state of knowledge regarding defense mechanisms and applies this information to estimate health risks to humans exposed to substances that alter genetic material. Recognized experts document, to a large extent, which carcinogens can cause injury to human beings and their surroundings, providing guidance for the structured acquisition of key information to reduce cancer risks throughout the environment.
Teaching morally and teaching morality are understood as mutually dependent processes necessary for providing moral education, or the communication of messages and lessons on what is right, good and virtuous in a student’s character. This comprehensive and contextualized volume offers anecdotes and experiences on how an elementary schoolteacher envisions, enacts, and reflects on the ethical teaching and learning of her students. By employing a personally developed form of moral education that is not defined by any particular philosophical or theoretical orientation, this volume relates that classroom-based moral education can, therefore, be conceived of and promoted as moral agency. Accentuated by the teacher’s voice to offer the experience of being in the classroom, this volume enables others to transfer relevant practices to their own teaching contexts.
Molecular Biology and Toxicology of Metals provides a critical review and analysis of the current state of knowledge of metal ion transport and metabolism in prokaryotic and eukaryotic cellular systems. It covers the latest information on specific metals and the biological molecules with which metals interact. It also details mechanisms in the handling and toxicity of metals in specific organ systems, and the role of metals in cell signalling and gene transcription in target cells. This book is sure to prove a fertile meeting ground for the disciplines of molecular genetics and metal toxicology.