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Nutraceuticals in Cardiovascular Diseases and their Associated Risk Conditions
Cardiovascular diseases and their associated risk conditions including dyslipidemia, hypertension and diabetes are one of the main health issues worldwide. The mechanisms underlying cardiovascular disorders are complex and multifactorial including oxidative stress, inflammation and mitochondrial dysfunction as well as modulating the activities of several kinases and phosphatases. Importantly, pharmacotherapies available for the management of these diseases are considered insufficient and show several limitations and side effects especially in high risk patients. Nutraceuticals are bioactive food components or phytochemicals that provide benefits including the prevention or treatment of several diseases. Nutraceuticals such as flavonoids, vitamins and other natural substances have shown pleiotropic antioxidant and anti-inflammatory properties.
Anti-inflammatory drug development focusing on immune mediated diseases
There are many immune mediated diseases with a well-known pathophysiology that have neither a safe and effective treatment, or whose available drugs are efficient but present an elevated toxicity. Immunopathologies affect approximately 3 - 5% of the general population.
Innovative Mobile and Internet Services in Ubiquitous Computing
This book highlights the latest research findings, methods and techniques, as well as challenges and solutions related to Ubiquitous and Pervasive Computing (UPC). In this regard, it employs both theoretical and practical perspectives, and places special emphasis on innovative, mobile and internet services. With the proliferation of wireless technologies and electronic devices, there is a rapidly growing interest in Ubiquitous and Pervasive Computing (UPC). UPC makes it possible to create a human-oriented computing environment in which computer chips are embedded in everyday objects and interact with the physical world. Through UPC, people can remain online even while underway, thus enjoying nearly permanent access to their preferred services. Though it has a great potential to revolutionize our lives, UPC also poses a number of new research challenges.
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