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Protecting the natural environment and promoting sustainability have become important objectives, but achieving such goals presents myriad challenges for even the most committed environmentalist. American Environmentalism: Philosophy, History, and Public Policy examines whether competing interests can be reconciled while developing consistent, coherent, effective public policy to regulate uses and protection of the natural environment without destroying the national economy. It then reviews a range of possible solutions. The book delves into key normative concepts that undergird American perspectives on nature by providing an overview of philosophical concepts found in the western intellectu...
Of the world’s seven continents, Asia is the largest. Its physical landscapes, political units, and ethnic groups are both wide-ranging and many. Southwest, South and Middle Asia are highly populated regions which, as a whole, cover an extremely large area of varied geography. In total, this domain is unique in its plant diversity and large vegetation zones with different communities and biomes. It is rich in endemics, with specific and intraspecific diversity of fruit trees and medicinal plants, including a number of rare, high value, species. At the same time, much of the land in the region is too dry or too rugged, with many geographical extremes. Overgrazing, oil and mineral extraction...
The adaptive immune resistance (AIR) mechanism refers to the various strategies employed by tumours to adapt and ultimately to overcome immune attack. The AIR mechanism was firstly identified in the selective induction of programmed cell death 1 ligand 1 (PDL1) by interferon gamma of tumors. The inhibition of adaptive immune resistance underlies the responses to PD-1 or PD-L1–blocking antibodies, and may have relevance for the development of other cancer immunotherapy strategies. Therefore, identifying specific AIR mechanisms is of great significance to develop novel drugs and enhance the efficacy of cancer treatment. In this research topic, we aim to generate a collection of articles that discuss the AIR mechanisms, the classification of AIRs, and the current and future cancer therapy strategies based on AIR. Of particular, these articles can focus on exploring the AIR mechanisms in different cancer types and further identify the association between AIR and tumour microenvironment (TME).
This is a study of the nature of Ottoman administration under Sultan Abdulhamid and the effects of this on the three provinces that were to form the modern state of Iraq. The author provides a general commentary on the late Ottoman provincial administration and a comprehensive picture of the nature of its interaction with provincial society. In drawing on sources of the Ottoman archives, bringing together and analyzing an abundance of complex documents, this book is a fascinating contribution to the field of Middle Eastern studies.
This collection of essays on Islamic art and architecture in the nineteenth century covers a wide geographical area and draws together different regional elements. The essays devote much attention to social, political, economic and intellectual issues, including the role of tradition and responses to European aesthetics, among them the appropriation of orientalism and the rise of revivalist movements.
Presents a comprehensive A-to-Z reference to the empire that once encompassed large parts of the modern-day Middle East, North Africa, and southeastern Europe.
Want to tap the power behind search rankings, product recommendations, social bookmarking, and online matchmaking? This fascinating book demonstrates how you can build Web 2.0 applications to mine the enormous amount of data created by people on the Internet. With the sophisticated algorithms in this book, you can write smart programs to access interesting datasets from other web sites, collect data from users of your own applications, and analyze and understand the data once you've found it. Programming Collective Intelligence takes you into the world of machine learning and statistics, and explains how to draw conclusions about user experience, marketing, personal tastes, and human behavio...