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Biological Insights of Multi-Omics Technologies in Human Diseases
  • Language: en
  • Pages: 420

Biological Insights of Multi-Omics Technologies in Human Diseases

  • Type: Book
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  • Published: 2024-05-23
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  • Publisher: Elsevier

"Biological Insights of Multi-Omics Technologies in Human Diseases ́ provides detailed information about the basics of multi-omic technologies including ethics, historical perspective, science, drug discovery, and development and metabolism. With a strong focus on the practical application of omics approaches in cancer, cardiovascular, neurology, respiratory, viral, gastroenterology, autoimmune diseases, PCOS and tuberculosis, this book also includes special topics related to COVID-19 and Machine learning approaches. In 13 chapters this book provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of multi-omics from academic, regulatory, pharm...

Pharmacogenomics
  • Language: en
  • Pages: 392

Pharmacogenomics

  • Type: Book
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  • Published: 2023-06-13
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  • Publisher: Elsevier

Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The editors lined up a group of worldwide experts to contribute to the book. Following a consistent chapter structure, the authors cover the foundational aspects of pharmacogenomics in the first four chapters of the book that include basic concepts, drug metabolism, drug discovery and development, and testing. The second part of the book is dedicated to detailed studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, p...

Genetic Polymorphism and Disease
  • Language: en
  • Pages: 1256

Genetic Polymorphism and Disease

  • Type: Book
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  • Published: 2022-12-06
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  • Publisher: CRC Press

Genetic polymorphisms are important determinants of phenotypic variations and may modulate the risk to or even cause various diseases including genetic disorders and multifactorial diseases. Genetic polymorphisms also serve as important genetic, population and evolutionary markers that allow the study of genetic and evolutionary aspects of individuals, populations and organisms and aid in tracing the evolutionary and parental lineages. Genetic polymorphisms in low penetrance genes are responsible for the alterations in the gene expression of critical signal transduction proteins and metabolic enzymes. Some of these polymorphisms are linked to increased susceptibility to various diseases espe...

Genetic Polymorphism and cancer susceptibility
  • Language: en
  • Pages: 353

Genetic Polymorphism and cancer susceptibility

This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field.

Nutrition and Obsessive-Compulsive Disorder
  • Language: en
  • Pages: 398

Nutrition and Obsessive-Compulsive Disorder

  • Type: Book
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  • Published: 2023-11-15
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  • Publisher: CRC Press

Key features – Covers emerging therapeutic and nutritional approaches for the treatment and management of OCD Reviews the role of various micro-nutrients in OCD Discusses the prenatal genetic diagnosis and application of computational modelling in OCD Includes the nutritional and dietary roles in neuropsychiatric disorders like depression and obsessive-compulsive disorder (OCD) Explores the application of nano-biotechnology in OCD

Public Health, Public Health Education, and their Future Prospects
  • Language: en
  • Pages: 206

Public Health, Public Health Education, and their Future Prospects

A number of studies have pointed out that currently, medical schools may have failed to supply self-directed lifelong learners and qualified healthcare workers. Therefore, in recent years, the medical teaching modes have been consistently reformed. The new generation of novel education modes such as Research-Based Learning (RBL), Problem-Based Learning PBL), Team-Based Learning (TBL) have the characteristics of universality, interactivity, and promptness, which empower instructors and students to learn and grow together. Moreover, the reform of medical teaching modes has been significantly facilitated in the COVID19 era due to public’s rising awareness of public health and more obviously, pandemic prevention policies such as travel restrictions. For instance, many countries have launched remote teaching mode in order to provide consistent education service with high quality. These novel teaching modes can provide amelioration to the traditional education modes and may lead the education system to another prosperity.

Proteomics
  • Language: en
  • Pages: 414

Proteomics

  • Type: Book
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  • Published: 2023-02-14
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  • Publisher: Elsevier

Proteomics: A Promising Approach for Cancer Research provides an updated overview of scientific knowledge, achievements and findings in the field of cancer proteomics. The book discusses topics such as the use of proteomics in cancer biology and drug discovery, its role in surgical oncology, applications of mass spectrometry, target proteomics, single-cell proteomics, and next-generation proteomics. In addition, it discusses proteomics and phosphor-proteomics in cancer precision medicine; translation of proteomics research into clinical application; and challenges and future developments of the field. This will be a valuable resource for cancer researchers, oncologists, graduate students, an...

Therapeutic Applications of Honey and its Phytochemicals
  • Language: en
  • Pages: 453

Therapeutic Applications of Honey and its Phytochemicals

Honey typically has a complex chemical and biochemical composition that invariably includes complex sugars, specific proteins, amino acids, phenols, vitamins, and rare minerals. It is reported to be beneficial in the treatment of various diseases, such as those affecting the respiratory, cardiovascular, gastrointestinal, and nervous systems, as well as diabetes mellitus and certain types of cancers; however, there is limited literature describing the use of honey in modern medicine. This book provides evidence-based information on the pharmaceutical potential of honey along with its therapeutic applications and precise mechanisms of action. It discusses in detail the phytochemistry and pharmacological properties of honey, highlighting the economic and culturally significant medicinal uses of honey and comprehensively reviewing the scientific research on the traditional uses, chemical composition, scientific validation, and general pharmacognostical characteristics. Given its scope, it is a valuable tool for researchers and scientists interested in drug discovery and the chemistry and pharmacology of honey.

Immunogenetics: A Molecular and Clinical Overview
  • Language: en
  • Pages: 427

Immunogenetics: A Molecular and Clinical Overview

Clinical Applications of Immunogenetics: Immunogenetics: A Molecular and Clinical Overview, Volume II provides readers with an exclusive, updated overview of scientific knowledge, achievements and findings in the field of immunogenetics. In thirteen chapters, the book gives insights in new advancements and approaches in viral and autoimmune diseases. Specific chapters are dedicated to immunogenetic mechanisms in the treatment of immune disorders, cancer, neurological and neurodegenerative disorders. In addition, other chapters cover immunogenomics in precision medicine, clinical medicine and transplantation. Finally, a special chapter, COVID-19: A novel challenge to human immune-genetic machinery, updates on thoughts surrounding the pandemic. - Contains exclusive information about global research on immunogenetics - Provides a solid foundation to researchers wanting to work on immunogenetics and their application in different autoimmune, viral and infectious diseases - Delivers information in a meticulous, attractive manner using pictures, illustrations and tables - Gives insights into immunogenetics and its utility in therapeutics

Phytomedicine
  • Language: en
  • Pages: 776

Phytomedicine

Phytomedicine: A Treasure of Pharmacologically Active Products from Plants aims to present updated knowledge of plant-based medicines in terms of their research and development, production, and utilization, from the viewpoint of sustainability and by using the latest technologies. The book explores different phytometabolites on a mass scale, coupled with the efficacy, performance and applicability on target organisms to treat curable and fatal diseases. Readers will find a coherent package of phytotherapeutic information regarding inclusive assortment of research based, scientific amplitude of metabolites from the plant world encompassing various action plans. Information is presented sequen...