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From Molecule to Men
From molecule to man: Medical research has indeed taken this direction, and major improvements of our understanding of the pathophysiology and epidemiology of disease have been achieved. The molecular basis of the congenital cardiovascular disorders has been extended from relatively few congenital malformations into everyday illnesses such as diabetes mellitus, hyperlipoproteinaemea, and arterial hypertension. The monogenic and, more difficult, polygenic basis for a vast majority of cardiovascular disorders are being defined more precisely from year to year. This book gives an overview of what has been achieved so far and defines the current position.
Circadian Clocks and Their Adjustment
Prestigious contributors describe the genetic, molecular, anatomical and neurochemical mechanisms and pathways that operate to regulate and control circadian rhythmicity and functioning in organisms ranging from unicellular algae to human beings. Also considers the implications of the basic and clinical research for humans.
Music that works
Many different disciplines are analyzing the impact of music today. How and why this ancient cultural asset molds, empowers and makes use of us can only become apparent in a synopsis and exchange involving scientific research. With this perspective as its foundation, the conference "Mozart and Science" extended invitations to the first interdisciplinary and international dialogue between the social and physical sciences about the effects of music. This book is based on the results of that congress. It contains contributions penned by leading scientists from around the world belonging to diverse music science disciplines and in particular covers psycho-physiological, neuro-developmental and cognitive aspects associated with the experience of music. Additional essays provide insights into research conducted about how music is applied in therapy and medicine.
Advances in Noninvasive Electrocardiographic Monitoring Techniques
Noninvasive electrocardiographic monitoring is a fundamental part of cardiology. Depending on continuous improvements and developments of new technologies, these methods are essential for diagnosis and risk stratification of patients. The rapid changes in the capabilities, technologies and diagnostic values of the different methods force us to update our knowledge continuously. This book offers a comprehensive overview of the current state and future developments in the field of noninvasive electrocardiographic monitoring techniques. In addition, related fields such as magnetocardiography, newer signal detection and analysis techniques as well as ambulatory blood pressure monitoring are repo...
Chronotherapeutics
In nature, many physical processes are governed by the passage of time. The study of these processes - chronobiology - reveals rhythmic patterns which may be yearly, monthly, daily or more frequent. Novel drug delivery systems are currently being delivered that will release varying quantities of a drug at optimum times to coincide with these rhythmic patterns.Chronotherapeutics considers the pharmaceutical and therapeutic implications associated with biological clocks. The book presents a comprehensive discussion of specific diseases that are time dependent, and the drugs and new drug formulations that can be used as treatments.Written by leading international experts in the field, Chronotherapeutics provides up-to-date information on chronobiology for non-chronobiologists in pharmaceutical and medical sciences. Peter Redfern is Professor of Pharmacology at the University of Bath, UK.
Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics
This is a newly updated second edition of Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics. William B. White, MD, and a panel of highly experienced clinicians critically review every aspect of out-of-office evaluation of blood pressure. The world-class opinion leaders writing here describe the significant advances in our understanding of the circadian pathophysiology of cardiovascular disorders.
Biologic Rhythms in Clinical and Laboratory Medicine
Everyone has heard of nature's "biological clocks", the phenomenon of periodic activity in plants, animals and humans. But what does chronobiology have to do with modern medicine? This book presents in a concise but comprehensive fashion the basic principles of chronobiology and their application to clinical medicine. The chapters are written by specialists in the field; they summarize the physiology, pathophysiology and pathology of the human time structure and outline the application of chronobiologic principles and techniques for diagnosis and treatment.
Chronopharmaceutics
Chronopharmaceutics Science and Technology for Biological Rhythm Guided Therapy and Prevention of Diseases Edited by Bi-Botti C. Youan The first standard reference on chronopharmaceutics As we better understand how biological processes unfold in real time through advances in chronobiology and related fields, we can create safer, more effective drugs, drug delivery systems, and disease monitoring and prevention systems. When administered in correct coordination with a patient's body rhythms, such drugs can maximize therapeutic outcome while minimizing unwanted side effects. Chronopharmaceutics presents the first standard reference text on this emerging cross-disciplinary field and its potenti...
Biopharmaceutics Modeling and Simulations
A comprehensive introduction to using modeling and simulation programs in drug discovery and development Biopharmaceutical modeling has become integral to the design and development of new drugs. Influencing key aspects of the development process, including drug substance design, formulation design, and toxicological exposure assessment, biopharmaceutical modeling is now seen as the linchpin to a drug's future success. And while there are a number of commercially available software programs for drug modeling, there has not been a single resource guiding pharmaceutical professionals to the actual tools and practices needed to design and test safe drugs. A guide to the basics of modeling and s...
Annual Reports in Medicinal Chemistry
Annual Reports in Medicinal Chemistry
