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Tumor Response Monitoring and Treatment Planning
Medical imaging progressed to a standard undreamt of not very many years ago. The advances are due to continuous development of radiological techniques and the introduction of magnetic resonance imaging. With the improved and new methods three-dimensional target volumes for radiation therapy can be defined with hitherto unknown precision. This leads to an improvement in irradiation techniques and, as a consequence, to a higher likelihood of tumor control and a lower risk of normal tissue complications. Besides the improvement in irradiation techniques the new imaging methods may enable great strides in tumor response monitoring, not only in the detection of morphological alterations but also by showing physiological changes in the tumor during and after treatment by means of MRI and PET. This not only leads to better prognostic information but may also allow early evaluation of the response to treatment. It may then be possible to individualize the radiation dose but also the alternative-treatment for non-responders. This is certainly a future direction for radiation oncology.
Stereotactic Neuro-Radio-Surgery
During the last few years stereotactic radiosurgery has become a partner of equal rank within the discipline of neurosurgery. Today it is regarded as being of the same importance as microsurgery and endovascular neurosurgery, branches which have also progressed rapidly in recent years. Breakthrough success, however, requires a combined effort of all partners involved. The editors have brought together leading experts in the fields of neurosurgery, neuroradiology, neurology, neuropathology, neuroanatomy, radiation oncology, and biophysics to discuss indications and therapeutic strategies in the treatment of arteriovenous malformations and intracranial tumors and to find a common basis for their future work.
Radiosurgery
How to avoid and manage complications in stereotactic radiosurgery? The most current and exciting developments as well as essential findings on refinements are published in this new volume. It addresses topics such as benign and malignant tumor radiosurgery, trigeminal neuralgia and headache, spectroscopic imaging, new hardware assessments, extracranial radiosurgery, and vascular malformations. The high-quality peer-reviewed reports were presented by experts in their field at the 2003 meeting of the International Stereotactic Radiosurgery Society. This publication is of special interest to neurosurgeons, radiation oncologists, medical physicists, neurologists, and oncologists, who require precise information to keep up to date with the important developments on the use of stereotactic radiosurgery.
When Cancer Crosses Disciplines
Ever wondered if your patient''s new symptoms are a manifestation of metastatic disease, treatment effects or are altogether unrelated to the cancer diagnosis; whether herbal remedies interact with cancer treatment; when to refer for genetic testing; or how to provide informed advice regarding dietary and lifestyle modifications?. This volume answers these and many other questions, spanning from cancer prevention to palliative care. Each chapter is comprehensively referenced, to allow the reader to explore related fields in more detail. The book is unique in summarizing a large amount of information that is beyond conventional oncology textbooks. While cancer is treated by multidisciplinary ...
Neuroanatomy for the Neuroscientist
In this day where research grants are the primary focus, many young investigators are thrown into neurosciences courses without any prior preparation in neuroanatomy. This book is designed to help prepare them by introducing many of the fundamentals of the nervous system. It represents the essentials of an upper level biology course on the central nervous system. It is not designed to be a clinical approach to the nervous system, but rather it approaches the nervous system from a basic science perspective that intertwines both structure and function as an organizing teaching and learning model. Medical and dental examples are included but the main focus is on neuroscience.
Neurosurgery of Arteriovenous Malformations and Fistulas
Arteriovenous malformations (AVM) and arteriovenous fistulas (AVF) differ from all other pathology affecting the central nervous system by their high-flow arteriovenous shunts. Permanent occlusion of these shunts is the essence and the challenge of therapy. Endovascular therapy and radiosurgery became accepted alternatives or adjuncts to surgery. In many instances the choice of the primary therapeutic modality is not clear and arguments can be found for several options. However, microsurgery, endovascular therapy and radiosurgery differ very much with regard to invasiveness, length of stay at the hospital but also residual risk after therapy. The emerging treatment concepts are the object of this book. The result is a unique structured presentation of AVM and AVF therapy.
Stereotactic Body Radiation Therapy
Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
Vesicles
"Offers a concise, logically organized survey of vesicular science and the practical applications of vesicles--including the latest advances in drug delivery. Contains over 2500 helpful citations to the literature, more than 220 drawings and photographs, many in color, and some 350 equations. Presents important topics that indicate the current scope and direction of vesicular research."
Gamma Knife Neurosurgery
Today, over 500,000 patients have been treated world wide in 250 Gamma Knife Centres in 37 countries each one treating between 150 and 700 patients a year. The current book serves as a textbook, training manual and reference book for those involved in Gamma Knife practice covering the theoretical background, the practical aspects of treatment, the social side of the method and necessary information not only for users but for those who refer to the Gamma Knife. It also covers some aspects of the hospital and social administration required for optimal use of the technology, also looking at the effect of the internet on specialist medical practice. It also presents the completely new Gamma Knife (Perfexion), a new technology which extends the range of the Gamma Knife and will be the treatment standard for the future.
Current and Future Management of Brain Metastasis
Latest guidelines for disease control of brain metastasis Recent strategies combining multiple modalities have opened up a whole new field of brain metastasis management focusing on disease control. The management of brain metastasis in modern times is no longer confined to palliation but seeks preservation of life quality and not only prolonged survival. Up-to-date guidelines and the main aspects of brain metastasis management as well as practical points on how to deal with difficult situations in daily clinical practice are presented. Epidemiology and biology and various effective treatment methods such as surgery, radiosurgery, radiation therapy and chemotherapy are well explained. Each chapter encompasses extensive reviews and presents broad perspectives on specific topics by the most renowned personages who have continuously shown their excellence in this rapidly progressing field. This book contains the most current information on the understanding of brain metastasis management. It is valuable reading for neurosurgeons, neuro-oncologists and radiation oncologists who are searching for the best all-round treatment for their patients.
