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Principles of Toxicology
Toxicology studies the injurious effects of chemical and physical agents (including energy) on living organisms, observed as alterations in structure and function. The variety of injurious effects becomes apparent if we examine the major causes of death (Fl .I). Many of these diseases are caused or accelerated by exposure to toxic substances. Toxicity data from various bio-medical sciences document the effects of exposure to natural or artificial agents. Textbook Contents 1. Scope of Toxicology 2. Risk Assessment 3. Targets and Bio-Transformation 4. Toxicokinetics 5. Hemato- and Vascular Toxicity 6. Dermatotoxicity 7. Neurotoxicity 8. Hepatotoxicity 9. Nephrotoxicity 10. Techniques In Vivo & In Vitro 11 . Pulmonary Toxicity 12. Reproductive Toxicity 13. Geno toxicity 14. Carcinogenicity For free PDF version http: //textbookequity.org/principles-of-toxicology/"
Principles and Methods of Toxicology
Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanis
Alternatives for Managing the Nation's Complex Contaminated Groundwater Sites
Across the United States, thousands of hazardous waste sites are contaminated with chemicals that prevent the underlying groundwater from meeting drinking water standards. These include Superfund sites and other facilities that handle and dispose of hazardous waste, active and inactive dry cleaners, and leaking underground storage tanks; many are at federal facilities such as military installations. While many sites have been closed over the past 30 years through cleanup programs run by the U.S. Department of Defense, the U.S. EPA, and other state and federal agencies, the remaining caseload is much more difficult to address because the nature of the contamination and subsurface conditions m...
Hayes' Principles and Methods of Toxicology
Hayes’ Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition of new authors while maintaining the same high standards that have made this book a benchmark resource in the field. Key Features: The comprehensive yet concise coverage of various aspects of fundamental and applied toxicology makes this book a valuable resource for educators, students, and professionals. Questions provided at the end of each chapter allow readers to test their knowledge and understanding of the material covered. All chapters ...
Metal Toxicology
Metal Toxicology addresses the effects of metals on human health, as well as their mechanisms of toxicity. Unlike most books on metal toxicity which are organized by individual metals, this book is arranged inan organ-by-organ basis. It deals with unifying mechanisms of metal toxicity within a given tissue, and with exposure of a tissue to more than one metal at a time.Unique aspect of organ-specific orientationWritten by leading authorities in metal toxicologyChapters of special interest include Risk Assessment, Emerging Technologies, and Molecular Biological TechniquesServes as an excellent sourcebook of generalized information on metal toxicology, allowing for specific tissue-system referencing
Toxicology of Inhaled Materials
This book deals with the methods and scientific basis of inhalation toxicology. It describes devices and facilities needed to expose animals to inhaled particles and gases as well as approaches to estimating or measuring the fraction of the inhaled material that is retained in the respiratory tract. The book then reviews the evergrowing repertoire of techniques that can be used to measure the responses elicited by the exposure. Quantitative and qualitative anatomical, physiological, and biochemical strategies are discussed in detail. We believe that the toxicology of inhaled materials is an important and timely topic for several'reasons. During the past decade, morbidity and mortality attrib...
