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Insights into the Effectiveness of Exercise/Lifestyle Recommendations in Primary Care
The World Health Organization (WHO) reported that physical activity is one of the leading risk factors for non-communicable disease deaths worldwide. Several studies have shown that physical activity can reduce the risk of conditions such as heart disease, stroke and diabetes. Furthermore, exercise has been found to be beneficial in certain mental health conditions and improving the quality of life in patients undergoing cancer treatment. However, WHO estimates that 1 in 4 adults worldwide are not physically active enough. This has led to the development of the WHO global action plan on increasing physical activity, which includes integrating physical activity into primary health care. Globa...
Autoantibodies for Diagnostics, Prognostics, and Surveillance in Autoimmune Disease
Presence of autoantibodies is usually a sign of autoimmune disease, although low levels of autoantibodies may also be found in healthy individuals. The discovery of autoantibodies and their associations with autoimmune disease have improved the knowledge of disease mechanisms in autoimmunity as well as clinical diagnostics over the years. Lack of immune tolerance and increased production of antibodies directed against self-antigens may induce or drive autoimmune disease as clearly demonstrated for TSH receptor antibodies in Graves’ disease. Autoantibodies could also be a biomarker of an autoimmune disease, but without distinct pathophysiologic relevance; this could be exemplified by smooth...
