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Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. Aimed at medical professionals and pharmaceutical specialists, this book integrates extracellular and intracellular signalling processes and offers a fresh perspective on new drug targets.
Should Anne risk arrest and scandal to help a fugitive escape? Her decision will change her life. In 1628, with England torn by conflict, fifteen-year old Anne Dudley helps a rebel escape from Tattershall Castle through the watery fens. Pursued by the sheriff and his men, who view her Puritan family as traitors to the king, Anne risks more than the loss of her reputation as the daughter of the earl's steward - she also risks death. Set in a period when women and men were burned or hanged for their religion, the novel tells the story of a girl who must cope with a woman’s feelings while she struggles with romantic turmoil, political danger, and doubts about her own beliefs. When she takes up her pen, we glimpse the grown Anne Dudley Bradstreet, whose Colonial writings are still loved and honored today. From a talented new voice in historical fiction, Gretchen Gibbs’ Anne of the Fens joins The Book of Maggie Bradstreet in The Bradstreet Chronicles. Records about the author's well-known ancestors give birth to her stories. Read the series—enriched by the historical content in each book's back pages—in any order.
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This masterful book from top experts provides clinical insights on reverse shoulder arthroplasty gleaned from hands-on refinement of shoulder replacement techniques. Years of significant biomechanical and clinical research yielded invaluable knowledge that led to important improvements in functional outcome and implant durability. Among these refinements were stronger polyethylene derivatives, better ingrowth technology, and improved connection devices. As the durability and longevity of implant technology increased, younger active patients became suitable candidates for this procedure. In fact, RSA has played a pivotal role in making shoulder arthroplasty the fastest growing implant technol...
Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Build your Foundation of Basic Science – from Research to Clinical Application A great tool for MOC preparation! A 'must have' for residency! This fourth edition, developed in a partnership between the American Academy of Orthopaedic Surgeons (AAOS) and the Orthopaedic Research Society (ORS), is your concise and clinically relevant resource for the diagnosis and treatment of musculoskeletal diseases and conditions.
The history of television in Chicago begins with the birth of the medium and is defined by the city's pioneering stations. WBKB (now WLS-TV) was the principal innovator of the Chicago School of Television, an improvisational production style that combined small budgets, personable talent, and the creative use of scenery and props. WNBQ (now WMAQ-TV) expanded the innovative concept to a wider audience via the NBC network. WGN-TV scored with sports and kids. Strong personalities drove the success of WBBM-TV. A noncommercial educational station, WTTW, and the city's first UHF station, WCIU, added diversity and ethnic programming. The airwaves in Chicago have been home to a wealth of talented performers and iconic programs that have made the city one of the country's greatest television towns. Chicago Television, featuring photographs from the archives of the Museum of Broadcast Communications (MBC) and the collections of local stations and historians, gives readers a front-row seat on a journey through the fi rst 50 years of Chicago television, 1940-1990. Founded in 1982 by broadcaster Bruce DuMont, the MBC Web site offers over 10,000 digital assets.
A transgenic organism is a plant, animal, bacterium, or other living organism that has had a foreign gene added to it by means of genetic engineering. Transgenic plants can arise by natural movement of genes between species, by cross-pollination based hybridization between different plant species (which is a common event in flowering plant evolution), or by laboratory manipulations by artificial insertion of genes from another species. Methods used in traditional breeding that generate transgenic plants by non-recombinant methods are widely familiar to professional plant scientists, and serve important roles in securing a sustainable future for agriculture by protecting crops from pest and h...
"Love is Eternal" was the inscription Abraham Lincoln had engraved on the wedding ring he gave Mary Todd. This book tells Mary's own story, especially her romance with Abraham and her years of marriage which were happier than historians generally believe.
Architectural discourse today is characterized by an overlapping conversation between architects and academics, teachers and students, theorists and practitioners. Crib Sheets is a guide - a crib - to twenty-two of those buzzwords (diagram; extreme form; autonomy and the generic), framing contemporary currents and trajectories.