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Jan Waldenström (1906-1996) was the leading Swedish internist of the twentieth century. The first chapter of the book presents his remarkable family including five generations of physicians. Born in Stockholm, we follow JW to medical school at Uppsala University during 1924–33. In 1934–5, he spent a year in the laboratory of Nobel Laureate Hans Fischer in Munich. In 1937, he defended a landmark thesis on acute intermittent porphyria. As “Docent” (assistant professor) in Uppsala, he discovered two new diseases in 1943. In 1944–5, he spent 7 months in the US commissioned by the Swedish Health Board. This started friendships with leading colleagues and scientists. With time, JW foste...
First multi-year cumulation covers six years: 1965-70.
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Circannual Clocks: Annual Biological Rhythms documents the Proceedings of a Satellite Symposium of the 140th Meeting of the American Association for the Advancement of Science held in San Francisco, California, February 25, 1974. The purpose of the symposium was to summarize the present state of knowledge on endogenous annual rhythms (circannual clocks), and to point out their biological significance and importance. The presentations included studies on the following: the circannual rhythms of an arthropod, the cave crayfish, Orconectes pellucidus inermis, and a cnidarian, Campanularia flexuosa; the occurrence, manifestation, and importance of circannual rhythms in birds with different migratory habits; and the importance of circannual rhythms in hibernating mammals. Also covered are the relationships between circannual rhythms and endogenous lunar and tidal rhythms; circannual rhythm of reproduction in male European starlings; the adaptational value of internal annual clocks in birds; the expression and suppression of the circannual antler growth cycle in deer; and circannual rhythms in man.
With the beginning of the 1980's it was becoming increasingly evident that the lack of approval of new cardiovascular agents for use by clinicians in the United States for the treatment of cardiovascular disorders was becoming a problem. Patients requiring medical therapy for hypertension, angina pectoris, arrhythmias, congestive heart failure, and vasospastic disorders of the coronary arteries could receive in the United States only a small number of the drugs available to physicians in the rest of the world. In fact, as the 1980's began, there was only one available beta blocking agent released by The Food and Drug Administration; and even as of this writing, no oral calcium antagonist age...