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Serotonin and the CNS
Serotonin is an ancient neurotransmitter system involved in various systems and functions in the body and plays an important role in health and disease. The present volume illustrates the broadness of the involvement of serotonergic activity in many processes, focusing particularly on disorders of the brain, including depression, stress and fear, Alzheimer’s disease, aggression, sexual behavior, and neuro-immune disorders. Chapters illustrate techniques and methods used to study the complex role of the serotonergic system in all kinds of processes, present new hypotheses for several brain disorders like sleep and depression, and use mathematical modeling as a tool to advance knowledge of the extremely complex brain and body processes.
Antidepressants
Major depression is a severe and prevalent brain disorder with a high disability burden, hence the push for effective treatments. Antidepressants have been around since the 1950s, and although current medications are much more effective than early ones, there is still much room for improvement. "Real" antidepressants, defined as those that "repair" or "improve" the depression-causing mechanism in the brains of depressed patients, have yet to be identified. This book presents current research on depression and antidepressants, including use of antidepressants in alcohol use disorders and pregnancy, treatment-resistant depression, and development of potential new medications.
Sexual Dysfunction
Sexual dysfunctions have a high prevalence in males and females, and an increase in research into its backgrounds, causes and treatment is clearly visible. Characterization of sexual dysfunctions is complex and often needs extensive clinical, psychological and psychiatric expertise to arrive at reliable diagnoses. The present volume illustrates various aspects involved in sexual (dys)functioning but also the complexity of the field. Premature ejaculation, erectile dysfunction, female interest/arousal disorder, hypogonadism, sexual side effects of antidepressants and circumcision are subject of the various contributions. The topics treated nicely illustrate the problems associated with sexual function and dysfunction, including lifestyle, biological, mental, sociocultural and religious aspects. The topics in this volume clearly demonstrate the importance of research on sexual functions and dysfunctions.
Serotonin and the CNS
Serotonin is an ancient neurotransmitter system involved in various systems and functions in the body and plays an important role in health and disease. The present volume illustrates the broadness of the involvement of serotonergic activity in many processes, focusing particularly on disorders of the brain, including depression, stress and fear, Alzheimer's disease, aggression, sexual behavior, and neuro-immune disorders. Chapters illustrate techniques and methods used to study the complex role of the serotonergic system in all kinds of processes, present new hypotheses for several brain disorders like sleep and depression, and use mathematical modeling as a tool to advance knowledge of the extremely complex brain and body processes.
COVID-19 Pandemic, Mental Health and Neuroscience
Even though knowledge about the impact of the pandemic on mental health is still very limited in all countries and is largely based on experiences only partially comparable to the current epidemic, such as those of the SARS or Ebola epidemics, it is likely that the need for intervention will increase significantly in the coming months and years. Scientific research in neuroscience is a growing field. It offers a novel perspective on the relationship between mind and brain and provides novel scenarios for understanding the long wave of the current pandemic. Furthermore, the pandemic has also led to the possibility of implementing remote monitoring and management interventions. This volume uses multidisciplinary approaches to physiological and cognitive mechanisms, medical treatment, psychosocial interventions, and self-management to help illustrate the complex association among the COVID-19 pandemic, neurological manifestations, mental health, and society.
Antidepressants
Major depression is a severe and prevalent brain disorder with a high disability burden, hence the push for effective treatments. Antidepressants have been around since the 1950s, and although current medications are much more effective than early ones, there is still much room for improvement. "Real" antidepressants, defined as those that "repair" or "improve" the depression-causing mechanism in the brains of depressed patients, have yet to be identified. This book presents current research on depression and antidepressants, including use of antidepressants in alcohol use disorders and pregnancy, treatment-resistant depression, and development of potential new medications.
Animal Models in Psychopharmacology
Invited main contributions and invited posters from a Satellite Meeting on [title] held July 1990 in Amsterdam as part of the 11th International Congress of Pharmacology. The central aim is the description and explanation of the developments in the various fields exploiting animal models for psychiatric disorders. The emphasis of this research focuses on three methodological disciplines--pharmacological, psychological, and ethological models--as applied to animal models of anxiety, depression, psychosis, aggression, and sexual behavior. Annotation copyrighted by Book News, Inc., Portland, OR
