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How Life Emerges from Inanimate Matter
  • Language: en
  • Pages: 458

How Life Emerges from Inanimate Matter

This book describes how the phenomenon of life emerges gradually from the elements of inanimate matter. It shows that, first, this transition occurs in space, when we move from elementary particles and atoms, through molecules and their complexes, cells, tissues and organs to entire individuals. Second, this transition also happened (and is still happening) in time, during biological evolution, when the first living systems originated spontaneously from organic compounds and then evolved step by step through bacteria to plants, animals and us. Third, the embryonic development from a fertilized egg to an adult individual occurs both in space and time. This book is unique as it analyzes all three processes in terms of their physical, chemical, biochemical, thermodynamic, energetic, genetic, cellular, physiological, embryological, evolutionary and cybernetic aspects.

From Neurons to Self-consciousness
  • Language: en

From Neurons to Self-consciousness

In the end, the author suggests that as more is learned about the working of the brain, philosophical problems that have caused centuries of speculation will simply be resolved by the facts of neurophysiology. --Book Jacket.

Metamorphoses of the Absolute
  • Language: en
  • Pages: 339

Metamorphoses of the Absolute

This collection of essays is devoted to the diversity of the conceptual and terminological definitions of the notion of the “absolute”. Absolute comprises both the concepts of the Western world related to God and the verbal constructions flowing from these ideas in the spheres of law, philosophy, linguistics, politics, medicine, literature, and arts. Over time, absolute and its neologisms have undergone various modifications, assuming the associated characteristics of syntactic ambiguity and inflation. Absolute can imply an increase in the degree of a quality attached to some object or phenomenon and can be used as either an adverbial modifier or a proper noun. In its appearances as a procedural term, absolute mostly conveys a negative connotation when evaluating some action. The question posed in this book is not what absolute is, but what possibilities exist with regard to perceiving and conceptualizing it in human terms, both historically and in the present.

Detection of Mitochondrial Diseases
  • Language: en
  • Pages: 317

Detection of Mitochondrial Diseases

In October 1995, the 1st Colloquium on Mitochondria and Myopathies in Halle/Saale was organized in Halle/Saale by the editors of this focused issue. The meeting took up what might be called an East German tradition: from 1976 to 1990 Andreas Schmidt organized seven clinically orientated Colloquia on Myology in Jena, and from 1974 to 1990 a series of twelve Colloquia on Mitochondria focused on basic research aspects was arranged by Wolfgang Kunz in Magdeburg. At those meetings, East Germany was a mediator between East European, West European and American scientists. In continuation of this tradition, scientists from more than 17 countries working on mitochondria as neurologists, biochemists, ...

Technological and Medical Implications of Metabolic Control Analysis
  • Language: en
  • Pages: 366

Technological and Medical Implications of Metabolic Control Analysis

Two decades have passed since the mechanisms of protein synthesis became well enough understood to permit the genetic modification oforganisms. An impressive amount of new knowledge has emerged from the new technology, but much ofthe promise of20years ago has notyet been fulfilled. In biotechnology, efforts to increase the yields of commercially valuable metabolites have been less successful than ex pected, and when they have succeeded it has often been as much from selective breeding as from new methods. The cell is more complicated than what is presented in the classical teaching of biochemistry, it contains more structure than was dreamed of 20 years ago, and the behaviour ofany systemofenzymes is more elaborate than can be explained in terms ofa single supposedly rate-limiting enzyme. Even if classical enzymology and meta bolism may have seemed rather unfashionable during the rise ofmolecular biology, they remain central to any modification ofthe metabolic behaviour oforganisms. As such modification is essential in much ofbiotechnology and drug development, bio technologists can only ignore these topics at their peril.

Music that works
  • Language: en
  • Pages: 340

Music that works

Many different disciplines are analyzing the impact of music today. How and why this ancient cultural asset molds, empowers and makes use of us can only become apparent in a synopsis and exchange involving scientific research. With this perspective as its foundation, the conference "Mozart and Science" extended invitations to the first interdisciplinary and international dialogue between the social and physical sciences about the effects of music. This book is based on the results of that congress. It contains contributions penned by leading scientists from around the world belonging to diverse music science disciplines and in particular covers psycho-physiological, neuro-developmental and cognitive aspects associated with the experience of music. Additional essays provide insights into research conducted about how music is applied in therapy and medicine.

Bioenergetics of the Cell: Quantitative Aspects
  • Language: en
  • Pages: 444

Bioenergetics of the Cell: Quantitative Aspects

This volume continues the discussion of the problems of in vivo and in vitro. The recently solved X-ray structure of the mitochondrial creatine kinase and its molecular biology cellular bioenergetics - the tradition we started in 1994 by publication of the focused issue of Molecular and Cellular are analyzed with respect to its molecular physiology and Biochemistry, volume 133/134 and a book 'Cellular Bio functional coupling to the adenine nucleotide translocase, as energetics: role of coupled creatine kinases' edited by V. Saks well as its participation, together with the adenylate kinase and R. Ventura-Clapier and published by Kluwer Publishers, system, in intracellular energy transfer. Th...

Modern Trends in Biothermokinetics
  • Language: en
  • Pages: 485

Modern Trends in Biothermokinetics

This book includes articles relating to presentations given in a variety of forms (lectures, posters, contributions to round tables, software presentations) at the 5th International Biothermokinetics Meeting held in Bordeaux-Bombannes, September 23-26, 1992. The fact that not just lectures were considered for these proceedings reflects the aims of BTK meetings to instigate discussion, promote scientific cooperation and confront as many different ideas as possible with each other (at best heretical ones). BTK conferences have expanded more and more; 130 participants came to the 1992 meeting from 20 countries. It was therefore necessary to hold the round tables in parallel sessions. It is difficult to have an unbiased feeling of what should be selected as the salient features of the meeting. As the name suggests, Biothermokinetics embraces thermodynamic and kinetic approaches to experimental and theoretical investigations of biological processes, in particular at the cellular level. This "classical" point of view is mainly represented in the chapter "Thermodynamics and Kinetics of Transport Processes and Biological Energy Transduction".

Oxygen Transport to Tissue XXIX
  • Language: en
  • Pages: 402

Oxygen Transport to Tissue XXIX

This comprehensive survey covers all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. Special attention is paid to methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. This multidisciplinary book is designed to bring together experts and students from a range of research fields.

Why speak?
  • Language: en
  • Pages: 271

Why speak?

This philosophical work is a research about the meaning and importance of language. The author investigates the different comprehensions about language through various civilizations and philosophies. She proposes to understand it as a technique for survival, allowing culture and democracy. She notes that, even if it may be used for manipulation and exploitation, it is the best tool for freedom.