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"This is the book edition of the Journal of Alzheimer's Disease, Volume 9, No.3 Supplement (2006)"--T.p. verso.
This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases.
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Genetic Aberrancies and Neurodegenerative Disorders presents critical reviews and emerging findings concerning the roles of genetic mutations and polymorphisms in the pathogenesis of a range of neurological disorders including Alzheimer's and Parkinson's diseases, trinucleotide repeat disorders, stroke, epilepsy and others. This volume, written by leading experts, brings together fundamental information concerning the roles of inherited traits in the pathogenesis of different neurodegenerative disorders. In addition to providing a catalogue of the known genetic alterations that are linked to specific neurodegenerative disorders, the chapters detail the current state of understanding of the c...
Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4, 1906 in Tübingen. The celebratory event "Alzheimer 100 Years and Beyond" was organized through the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen. This volume, a collection of articles by the invited speakers and of a few other prominent researchers, is published as a record of those events.
The Erice International Seminars are multidisciplinary seminars attended by over 100 eminent participants from all fields of science. Each year, a few scientific issues are selected and experts are invited to present contrasting views during the plenary multidisciplinary sessions of the seminar, followed by general debates. These sessions offer a unique opportunity for specialists to enlarge their vision of their related fields by being confronted with ideas and suggestions from high-level scientists in complementary domains of science. Associated workshops allow the experts to further refine and process the ideas evoked during the seminar. This year's topics are all actual. For instance, on climate issues we have focused on the management of a global warming and on new theoretical alternatives to climate modeling. On global monitoring of the planet, we have focused on the US missile defence shield, the energy externalities and waste disposal and the historical dive by Dr Chilingarov on the North Pole shelf. On the medical side, we have investigated the Alzheimer epidemics and the role of infectious agents in cancer.