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International Society for Affective Disorders (ISAD) exists to promote research into the mood (affective) disorders through all relevant scientific disciplines, including genetics, neuroscience and the social and behavioural sciences. Inter-disciplinary research approaches are particularly highly valued by the society. www.isad.org.uk
Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. - Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics - Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry - Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective
The world is witnessing a burgeoning global epidemic of chronic cerebro- and cardiovascular disease and depression disorders. The reader will find this comprehensive book to be a long-needed, up-to-date knowledge base on these increasingly recognized comorbid conditions that have long-term consequences for individual function and well-being and society in general. This comprehensive book outlines the complex and bidirectional relationship between various types of depression and cerebro- and cardiovascular diseases. It is written by a range of experts in the field, including psychiatrists, cardiologists, neuroscientists, psychologists, and epidemiologists, with the aim of presenting and discu...
The brain and immune system are involved in an intricate network of bidirectional communication. This relationship is vital for optimal physiological and psychological development and functioning but can also result in unwanted outcomes. In particular, this interaction plays an important role in cognition, mood and behaviour. Neuroinflammation is known to contribute to neurological and affective disorders including impaired learning and memory, depressive, anxiety and schizoaffective symptoms, as well as pain. The development of these conditions often occurs on the backdrop of pre-existing physical illnesses which give rise to increased activation of the immune system, such as cancer, obesit...
Inflammation has invaded the field of psychiatry. The finding that cytokines are elevated in various affective and psychotic disorders brings to the forefront the necessity of identifying the precise research domain criteria (RDoCs) that inflammation is responsible for. This task is certainly the most advanced in major depressive disorders. The reason is that a dearth of clinical and preclinical studies has demonstrated that inflammation can cause symptoms of depression and conversely, cytokine antagonists can attenuate symptoms of depression in medical and psychiatric patients with chronic low grade inflammation. Important knowledge has been gained on the symptom dimensions that inflammation is driving and the mechanisms of action of cytokines in the brain, providing new targets for drug research and development. The aim of the book “Inflammation-Associated Depression” is to present this field of research and its implications in a didactic and comprehensive manner to basic and clinical scientists, psychiatrists, physicians, and students at the graduate level.
Physical activity and exercise were receiving a great attention as a strategy of prevention and treatment of affective and some anxiety disorders. Many studies have showed the efficacy of exercise in major depression and at depressed episode of bipolar patients, as well as, some authors shows the benefits of exercise in some anxiety disorders like Generalized Anxiety Disorder and Panic. Despite their efficacy, little is known concerning the main mechanisms related to the antidepressant and anxiolytic effects of exercise. Several studies in an animal model using Neurotrophic Factors, Oxidative Stress, Immunologic response and other biological markers reveal promising results. However, few stu...
Recent advances in clinical psychiatry are presented by David Baron and Lawrence Gross in this issue of Psychiatric Clinics. Psychiatrists will find here disorders they deal with daily in patients and topics include Advances in: Addictive disorders; Geriatric and healthy aging; Trauma and violence; PTSD; Schizophrenia; Intellectual disabilities; Neuropsychiatry, Psychopharmacology; Integrated care - psychiatry and primary care; Global and cultural psychiatry; Mood disorders. Also presented are the Future role of psychotherapy in psychiatry; Public mental health in the Affordable Care Act era; Genetics; and Diagnostic classification (DSM criteria) how they are transitioning in future - DSM V and beyond.
The language of habit plays a central role in traditional accounts of the virtues, yet it has received only modest attention among contemporary scholars of philosophy, psychology, and religion. This volume explores the role of both “mere habits” and sophisticated habitus in the moral life. Beginning with an essay by Stanley Hauerwas and edited by Gregory R. Peterson, James A. Van Slyke, Michael L. Spezio, and Kevin S. Reimer, the volume explores the history of the virtues and habit in Christian thought, the contributions that psychology and neuroscience make to our understanding of habitus, freedom, and character formation, and the relation of habit and habitus to contemporary philosophical and theological accounts of character formation and the moral life. Contributors are: Joseph Bankard, Dennis Bielfeldt, Craig Boyd, Charlene Burns, Mark Graves, Brian Green, Stanley Hauerwas, Todd Junkins, Adam Martin, Darcia Narvaez, Gregory R. Peterson, Kevin S. Reimer, Lynn C. Reimer, Michael L. Spezio, Kevin Timpe, and George Tsakiridis.
"Major depressive disorder (MDD) is a mood disorder that consists of a variety of symptom clusters. While the traditional model of depression implicates mood as the primary symptom cluster, a recently published conceptual understanding of depression has been extended to consider cognitive function as a key symptom dimension in MDD. Part of the Oxford Psychiatry Library series, this handbook will provide clinicians with an overview of the clinical characteristics, assessment, and treatment of cognitive dimensions of MDD. It offers extended and novel diagnostic and treatment approaches ranging from pharmacological to psychological interventions targeting those dimensions of depression. Chapter...