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On August 7, 1975, Kohler and Milstein published in Nature (256:495) a report describing "Continuous cultures of fused cells secreting antibody of predefined specificity. " Their report has become a classic and has already had a profound effect on basic and applied research in biology and medicine. By the time the first Workshop on Lymphocyte Hybridomas (Current Topics in Microbiology and Im munology 81, 1978) was held on April 3-5, 1978, in Bethesda, Maryland, investi gators from many laboratories had made hybrids between plasmacytomas and spleen cells from immunized animals and had obtained monoclonal antibodies reacting with a broad variety of antigenic determinants. At the time Kohler an...
A fitness plan for everyone to shred stubborn areas of body fat and boost metabolism—no need to go to a gym Healthy Body educates you about your body, getting fit, and how to eat right for it. Once you understand the hormonal rules that govern your body you will become the master of your physique and the controller of your body. This book teachers readers how to shred stubborn areas of body fat, and what supplements to take for flabby arms, legs, and mid-section. It will teach you how to boost your metabolism with simple weight-based circuit-style training at home that will increase lean muscle while burning fat. It discusses simple everyday equipment list, weekly overviews, and 24 exercises. Lifestyle tips are offered, along with a meal plan and more than 30 recipes for breakfast, lunch, and dinner with post workout snacks and treats. Includes dual measures.
This book contains a love story that tells how the lives of two couples became so intertwined that there would not have been any story if that had not taken place. Even though much of the story involves those affiliated with a financial corporation and its subsidiary bank, this is not a book about investing, or the like, so much as it provides a window into relationships that can form from the interaction of people who work in the same environment and how each person has affected the life of another; about how a love that was lost a long time ago was found again, and how the spark of love exhibited by two people within a corporate environment could be ignited by the interaction of another. May you have as much pleasure reading this novel as I had in writing it. J. V. Perrone
Neurobiology of Disease is aimed at any basic scientist or clinician scientist teaching a course or conducting research on the basic science underlying the major neurological diseases. It provides an excellent overview of cutting-edge research on the fundamental disorders of the nervous system, including physiological and molecular aspects of dysfunction. The major categories of neurological disease are covered, and the chapters provide specific information about particular diseases exemplifying each of these categories. Sufficient clinical information is included to put into perspective the basic mechanisms discussed. The book assembles a world-class team of section editors and chapters written by acknowledged experts in their respective fields. - Provides cutting edge information about fundamental mechanisms underlying neurological diseases - Amply supplied with tables, illustrations and references - Includes supporting clinical information putting the mechanisms of disease into perspective
A bonus collection of one-minute mysteries and brain teasers.
A controversial, revisionist approach to autoimmune and allergic disorders considers the perspective that the human immune system has been disabled by twentieth-century hygiene and medical practices.
Are you battling an invisible enemy within your own body? Discover the shocking truth about why your immune system has turned against you - and learn how to reclaim your health and vitality. Imagine waking up every day feeling like you're trapped in a body that's fighting itself. Fatigue weighs you down, pain follows your every move, and a fog clouds your thoughts. You're not alone. Millions are caught in the autoimmune trap, struggling to understand why their own defense system has become their worst enemy. In "The Autoimmune Trap," unveils the hidden triggers that set off this internal war and provides a revolutionary roadmap to break free from the cycle of inflammation and illness. Drawin...
The book serves as a comprehensive resource for scientists and clinicians studying the role of non-coding RNAs in inflammation (viral infections, wound inflammation), human inflammatory diseases (i.e. rheumatoid arthritis, Crohn’s disease, diabetes) and innate immunity. It provides a universal reference work comprising both basic and specialized information. Given that ncRNAs represent new therapeutic targets, this volume will also be of interest to industrial biomedical researchers and those involved in drug development.