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Obesity is increasing in epidemic proportions worldwide. A low-grade inflammation caused by obesity leads to its many inflammation-associated complications, including insulin resistance, type 2 diabetes, accelerated atherosclerosis, nonalcoholic steatohepatitis that can lead to liver cirrhosis, heart failure, cancer, and Alzheimer’s disease. This systemic inflammation is due to profound changes in the adipose tissue microenvironment, at the heart of which is the adipocyte. Increasing evidence suggests the adipocyte not only stores excess energy, but initiates an escalating pro-inflammatory cascade in adipose tissue during high-fat diet. The adipocyte secretes over 50 cytokines and hormones that both enhance and suppress inflammation, secretes extracellular matrix proteins that impact inflammation, produces and releases toxic lipids that aggravate inflammation, and, more recently, was shown to present antigen to activate CD4+ T cells. Although discovered several decades ago, studies continue to identify pro-inflammatory roles for leptin and anti-inflammatory activities for adiponectin, hormones secreted in large amounts by the adipocyte.
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Covers the entire history of Freedom Movement in Vindhya region, which was later formed as Vindhya Pradesh by combining the princely states of Baghelkhand and Bundelkhand. Both the periods - the mutiny of 1857 as well as the Gandhian era have been described in detail. A flood light has been thrown on the various institutions related to freedom struggle: The Congress Party, All India States Peoples Conference, Students Organizations and Prajamandal etc. A description of secret Revolutionary Organization of Chandra Shekhar Azad, in Orchha, has also been given.
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Einer von drei Erwachsenen leidet gelegentlich oder häufig unter Ermüdungserscheinungen. Hinter dieser nüchternen Aussage verbergen sich oft verzweifelte Menschen, die emotional und körperlich ausgebrannt sind, keine Kraft für alltägliche Dinge haben, im Beruf nicht mehr voll leistungsfähig sind – und nicht wissen, woran es liegt. Ihnen fehlt es schlicht und einfach an Energie. Als immer mehr Patienten die Praxis von Dr. med. Steven Gundry aufsuchten, die über anhaltende Erschöpfung klagten, begann er, sich auf die Suche nach den Ursachen für diese neue Volkskrankheit zu begeben. Schließlich stellte er fest, dass die meisten seiner Patienten eines gemein hatten: Entzündungen im...
"Akashvani" (English) is a programme journal of ALL INDIA RADIO, it was formerly known as The Indian Listener. It used to serve the listener as a bradshaw of broadcasting ,and give listener the useful information in an interesting manner about programmes, who writes them, take part in them and produce them along with photographs of performing artists. It also contains the information of major changes in the policy and service of the organisation. The Indian Listener (fortnightly programme journal of AIR in English) published by The Indian State Broadcasting Service, Bombay, started on 22 December, 1935 and was the successor to the Indian Radio Times in English, which was published beginning ...
Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either g...
This book addresses aspects of rice production in rice-growing areas of the world including origin, history, role in global food security, cropping systems, management practices, production systems, cultivars, as well as fertilizer and pest management. As one of the three most important grain crops that helps to fulfill food needs all across the globe, rice plays a key role in the current and future food security of the world. Currently, no book covers all aspects of rice production in the rice-growing areas of world. This book fills that gap by highlighting the diverse production and management practices as well as the various rice genotypes in the salient, rice-producing areas in Asia, Europe, Africa, the Americas, and Australia. Further, this text highlights harvesting, threshing, processing, yields and rice products and future research needs. Supplemented with illustrations and tables, this text is essential for students taking courses in agronomy and production systems as well as for agricultural advisers, county agents, extension specialists, and professionals throughout the industry.