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Novel Synthetic Drugs in Migraine
Published in the series Headache, endorsed by the European Headache Federation, this is the first book on the novel synthetic treatment of migraine with ditans (lasmiditan) and gepants (atogepant, ubrogepant, rimegepant, vazegepant). These drugs will provide additional options for people with migraine put at risk of side effects by other medications or with unsatisfactory response to previous drugs. There is now a sufficient amount of literature published to interest a wide multidisciplinary readership (general physicians, general neurologists, clinical psychologists, neurologists in training, and medical students) facing every day this burdensome disorder in their clinical practice. The book aims therefore at offering an overview of these new drugs for both acute and prophylactic treatments of migraine, covering studies on clinical evidence, tolerability, and the different stages of clinical development.
Migraine Management
Migraine Management, Volume 196 covers the effective treatment of migraines, including different subtypes of migraines in different patient populations. The classification and diagnostic criteria of common and uncommon subtypes of migraine is explored in detail, including childhood variants. An in-depth analysis of the pharmacology of acute and prophylactic agents is presented, along with an evidence-based review of pharmacologic management. This includes recently developed CGRP monoclonal antibodies and non-peptide small molecule CGRP antagonists. Advances in neuromodulatory treatments, both noninvasive and implantable, are also critically reviewed. Finally, specific treatment-related issue...
Approach to the Psychiatric Patient
A fascinating text that addresses the clinical and educational challenges of treating psychiatric patients from a truly multidisciplinary perspective using a case-based format, Approach to the Psychiatric Patient: Case-Based Essays is the only book of its kind and an indispensable addition to the mental health practitioner's library. The new edition builds upon the strengths that distinguished the first, with composite cases that are carefully constructed to capture real-world problems, followed by essays that provide clear and cogent perspectives on the case. These essays cover a wide range, from the more conventional (such as differential diagnosis of anxiety or the clinical characteristic...
The Neurobiology and Treatment of OCD: Accelerating Progress
The book highlights important new research approaches of clinical relevance, written by prominent researchers in the field of OCD and related disorders. A broad range of topics is covered, beginning with a description of the phenotypic features of the OCD followed by chapters on developmental aspects, animal models, genetic and biological models including neuro-inflammation, functional neuroimaging correlates and information-processing accounts. Finally, existing and novel treatment approaches are covered including clinical and pharmacogenetic treatment models. In this way the volume brings together the key disciplines involved in the neurobiological understanding of OCD to provide an update of the field and outlook to the future. Together, the volume chapters provide focused and critical reviews that span a broad range of topics suitable for both students and established investigators and clinicians interested in the present state of OCD research.
Beetles
Describes the habitat, life cycle, behavior, predators, and unique characteristics of beetles.
Dulcan's Textbook of Child and Adolescent Psychiatry, Third Edition
"Dulcan's Textbook of Child and Adolescent Psychiatry provides in-depth, DSM-5-aligned evidence-based clinical guidance in such areas as neurodevelopmental and other psychiatric disorders; psychosocial treatments; pediatric psychopharmacology; and special topics, including cultural considerations, youth suicide, legal and ethical issues, and gender and sexual diversity. This third edition includes expanded information on telehealth, e-mental health, and pediatric consultation-liaison psychiatry"--
The Prevention and Treatment of Missing Data in Clinical Trials
Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and control groups, balancing out, on average, distributions of known and unknown factors among the participants. Unfortunately, these studies often lack a substantial percentage of data. This missing data reduces the benefit provided by the randomization and introduces potential biases in the comparison of the treatment groups. Missing data can arise for a variety of reasons, including the inability or unwillingness of participants to meet appointments for evaluation. And in some studies, some or all of data collection ceases when participa...
Obsessive-Compulsive Personality Disorder
"Obsessive-compulsive personality disorder (OCPD) is characterized by a pervasive and maladaptive pattern of excessive perfectionism, preoccupation with orderliness and details, and need for control over one's environment. It is the most common personality disorder and is associated with significant morbidity and increased health costs. Unfortunately, clinicians often do not diagnose OCPD or may incorrectly diagnose it as obsessive-compulsive disorder (OCD) or attention-deficit/hyperactivity disorder. Although progress has been made in understanding OCPD, many treatment providers do not know how best to address it clinically. This book examines treatment options along with developmental, psychological, and behavioral etiologies and the deeper neurobiological underpinnings of the disorder"--
