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Many physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.
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This book describes the fish which exhibit diadromy, their life history strategies and the implications for fisheries. The book should therefore represent an important volume for workers in fish biology, animal physiology and behaviour, and fisheries.
"In print, online, or on your mobile device, Principles and Practice of Pediatric Infectious Disease provides the comprehensive and actionable coverage you need to understand, diagnose, and manage the ever-changing, high-risk clinical problems caused by infectious diseases in children and adolescents. With new chapters, expanded and updated coverage, and increased worldwide perspectives, this authoritative medical reference offers the latest need-to-know information in an easily-accessible, high-yield format for quick answers and fast, effective intervention!"--Publisher's website.
Despite policy directives, standards and guidelines, indoor environmental quality is still poor in many cases. The Healthy Indoor Environment, winner of the 2016 IDEC Book Award, aims to help architects, building engineers and anyone concerned with the wellbeing of building occupants to better understand the effects of spending time in buildings on health and comfort. In three clear parts dedicated to mechanisms, assessment and analysis, the book looks at different indoor stressors and their effects on wellbeing in a variety of scenarios with a range of tools and methods. The book supports a more holistic way of evaluating indoor environments and argues that a clear understanding of how the ...
This open access book describes and illustrates the surgical techniques, implants, and technologies used for the purpose of personalized implantation of hip and knee components. This new and flourishing treatment philosophy offers important benefits over conventional systematic techniques, including component positioning appropriate to individual anatomy, improved surgical reproducibility and prosthetic performance, and a reduction in complications. The techniques described in the book aim to reproduce patients’ native anatomy and physiological joint laxity, thereby improving the prosthetic hip/knee kinematics and functional outcomes in the quest of the forgotten joint. They include kinema...
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.