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Bradley Shellito’s new textbook uses hands-on experience to introduce both the “how” and “why” of geographic information systems. Students learn to combine an understanding of basic GIS concepts with practical ArcGIS skills, following step-by-step instructions to accomplish a wide range of real-world tasks and applications while always keeping sight on the conceptual basis and practical impact of what they are doing. Discovering GIS and ArcGIS is appropriate for introductory GIS courses, or advanced or applied GIS courses. Instructors will find the coverage they need for a single intro-level course, a single advanced or applied course, or a two-course sequence.
This book captures cornerstone developments in a new body of knowledge and provides an expert resource on a “hot topic” in rectal surgery. Transanal minimally invasive surgery (TAMIS) was designed for local excision of select rectal neoplasms, however soon it became realized that the TAMIS technique could be used for applications beyond local excision, most notably for transanal total mesorectal excision (taTME). This new operative technique has revolutionized our approach to the distal rectum by allowing for improved access, especially in obese male patients with an android pelvis, and by minimizing abdominal wall access trauma. The endpoints of improved oncologic resection, as defin...
As Web service technologies have matured in recent years, an increasing number of geospatial Web services designed to deal with spatial information over the network have emerged. Geospatial Web Services: Advances in Information Interoperability provides relevant theoretical frameworks and the latest empirical research findings and applications in the area. This book highlights the strategic role of geospatial Web services in a distributed heterogeneous environment and the life cycle of geospatial Web services for building interoperable geospatial applications.
A comprehensive, state-of-the-art synthesis of biogeochemical dynamics and the impact of human alterations at major river-coastal interfaces for advanced students and researchers.
The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.
This cross-disciplinary volume incorporates diverse perspectives on mentoring undergraduate research, including work from scholars at many different types of academic institutions in Australia, Canada, the United Kingdom, and the United States. It strives to extend the conversation on mentoring undergraduate research to enable scholars in all disciplines and a variety of institutional contexts to critically examine mentoring practices and the role of mentored undergraduate research in higher education.