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As a major defence against environmental damage to cells DNA repair is present in all organisms including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. DNA repair is involved in processes that minimise cell killing, mutations, replication errors, persistence of DNA damage and genomic instability. Abnormalities in these processes have been implicated in cancer and ageing. This book presents leading-edge research from around the world in this frontal field.
This authoritative catalogue of the Corcoran Gallery of Art's renowned collection of pre-1945 American paintings will greatly enhance scholarly and public understanding of one of the finest and most important collections of historic American art in the world. Composed of more than 600 objects dating from 1740 to 1945.
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This historical explorationnbsp;details some of the most notorious scandals to have engulfed the British royal family and aristocracy, capturing not only the events and their era but also the essence of some of the world's greatest and most beautiful private dwellings. From the Hampton Court of Henry VIII to the modern scandals that saw the present Lord Brocket jailed, center stage is given to the British stately homes that have played witness to centuries of aristocratic indiscretion. Whether examining the "Profumo Affair," the call-girl scandal at Cliveden, the affairs of the lesbian Vita Sackville-West and her bisexual husband at Sissinghurst Castle, or the goings-on at Fort Belvedere, the Surreynbsp;hideaway where the Prince of Wales conducted his affair with the American divorcee Wallis Simpson,nbsp;this accountnbsp;provides a fascinating insight into the lives, loves—and morals, dubious though they may be—of some notorious denizens of the aristocratic world.