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Mathematical Modeling in Systems Biology
An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with...
Control Theory and Systems Biology
A survey of how engineering techniques from control and systems theory can be used to help biologists understand the behavior of cellular systems.
Modeling Life
This book develops the mathematical tools essential for students in the life sciences to describe interacting systems and predict their behavior. From predator-prey populations in an ecosystem, to hormone regulation within the body, the natural world abounds in dynamical systems that affect us profoundly. Complex feedback relations and counter-intuitive responses are common in nature; this book develops the quantitative skills needed to explore these interactions. Differential equations are the natural mathematical tool for quantifying change, and are the driving force throughout this book. The use of Euler’s method makes nonlinear examples tractable and accessible to a broad spectrum of e...
The Ecology of Collective Behavior
A groundbreaking new perspective on collective behavior across biological systems Collective behavior is everywhere in nature, from gene transcription and cancer cells to ant colonies and human societies. It operates without central control, using local interactions among participants to allow groups to adjust to changing conditions. The Ecology of Collective Behavior brings together ideas from evolutionary biology, network science, and dynamical systems to present an ecological approach to understanding how the interactions of individuals generate collective outcomes. Deborah Gordon argues that the starting point for explaining how collective behavior works in any natural system is to consi...
Simulation Algorithms for Computational Systems Biology
This book explains the state-of-the-art algorithms used to simulate biological dynamics. Each technique is theoretically introduced and applied to a set of modeling cases. Starting from basic simulation algorithms, the book also introduces more advanced techniques that support delays, diffusion in space, or that are based on hybrid simulation strategies. This is a valuable self-contained resource for graduate students and practitioners in computer science, biology and bioinformatics. An appendix covers the mathematical background, and the authors include further reading sections in each chapter.
Creating Local Arts Together
Creating Local Arts Together is a manual designed to guide an individual or group into a local community’s efforts at integrating its arts with the values and purposes of God’s kingdom. The practical, playful text reduces experience-based scholarly insights gained from multiple decades of incarnational ministry around the world into a flexible seven-step process. This manual is the second book in a two-volume set on the principles and practices of ethnodoxology. The first volume, entitled Worship and Mission for the Global Church: An Ethnodoxology Handbook, presents in textbook format the central “Foundations,” “Stories,” and “Tools” designed to equip readers in exploring more fully this important new field of research and ministry.
The Dhvanyāloka of Ānandavardhana with the Locana of Abhinavagupta
For nearly a thousand years the brilliant analysis of aesthetic experience set forth in the Locana of Abhinavagupta, India's founding literary critic, has dominated traditional Indian theory on poetics and aesthetics. The Locana, presented here in English translation for the first time, is a commentary on the ninth-century Dhvanyaloka of Anandavardhana, which is itself the pivotal work in the history of Indian poetics. The Dhvanyaloka revolutionized Sanskrit literary theory by proposing that the main goal of good poetry is the evocation of a mood or "flavor" (rasa) and that this process can be explained only by recognizing a semantic power beyond denotation and metaphor, namely, the power of...
How to Build a Brain
Chris Eliasmith presents a new approach to understanding the neural implementation of cognition in a way that is centrally driven by biological considerations. According to the Semantic Pointer Hypothesis, higher-level cognitive functions in biological systems are made possible by semantic pointers.
Ask a Manager
'I'm a HUGE fan of Alison Green's "Ask a Manager" column. This book is even better' Robert Sutton, author of The No Asshole Rule and The Asshole Survival Guide 'Ask A Manager is the book I wish I'd had in my desk drawer when I was starting out (or even, let's be honest, fifteen years in)' - Sarah Knight, New York Times bestselling author of The Life-Changing Magic of Not Giving a F*ck A witty, practical guide to navigating 200 difficult professional conversations Ten years as a workplace advice columnist has taught Alison Green that people avoid awkward conversations in the office because they don't know what to say. Thankfully, Alison does. In this incredibly helpful book, she takes on the ...
