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This book presents practical approaches for the analysis of data from gene expression micro-arrays. It describes the conceptual and methodological underpinning for a statistical tool and its implementation in software. The book includes coverage of various packages that are part of the Bioconductor project and several related R tools. The materials presented cover a range of software tools designed for varied audiences.
Placing data in the context of the scientific discovery of knowledge through experimentation, Practical Data Analysis for Designed Experiments examines issues of comparing groups and sorting out factor effects and the consequences of imbalance and nesting, then works through more practical applications of the theory. Written in a modern and accessible manner, this book is a useful blend of theory and methods. Exercises included in the text are based on real experiments and real data.
While numerous advanced statistical approaches have recently been developed for quantitative trait loci (QTL) mapping, the methods are scattered throughout the literature. Statistical Methods for QTL Mapping brings together many recent statistical techniques that address the data complexity of QTL mapping. After introducing basic genetics topics an
With many exciting enhancements and robust online resources, the seventh edition of Anatomy & Physiology for Speech, Language, and Hearing provides a solid foundation in anatomical and physiological principles relevant to the fields of speech-language pathology and audiology. This bestselling text is organized around the five “classic” systems of speech, language and hearing: the respiratory, phonatory, articulatory/resonatory, nervous, and auditory systems. Integrating clinical information with everyday experiences to reveal how anatomy and physiology relate to the speech, language, and hearing systems, the text introduces all the essential anatomy and physiology information in a carefu...
Designed for a graduate course in applied statistics, Nonparametric Methods in Statistics with SAS Applications teaches students how to apply nonparametric techniques to statistical data. It starts with the tests of hypotheses and moves on to regression modeling, time-to-event analysis, density estimation, and resampling methods.The text begins wit
This book explains how computer software is designed to perform the tasks required for sophisticated statistical analysis. For statisticians, it examines the nitty-gritty computational problems behind statistical methods. For mathematicians and computer scientists, it looks at the application of mathematical tools to statistical problems. The first half of the book offers a basic background in numerical analysis that emphasizes issues important to statisticians. The next several chapters cover a broad array of statistical tools, such as maximum likelihood and nonlinear regression. The author also treats the application of numerical tools; numerical integration and random number generation are explained in a unified manner reflecting complementary views of Monte Carlo methods. Each chapter contains exercises that range from simple questions to research problems. Most of the examples are accompanied by demonstration and source code available from the author's website. New in this second edition are demonstrations coded in R, as well as new sections on linear programming and the Nelder–Mead search algorithm.