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Since its introduction 52 years ago, Leksell radiosurgery has become a widely applied technique for the management of a diverse group of vascular, neoplastic, and functional disorders. This publication presents an update on state-of-the-art radiosurgery technology, including outcomes, by the pioneers in the field. Experts have contributed chapters on various topics. They provide a history of the development of Leksell Gamma Knife and its evolution from frame-based to the inclusion of mask-based radiosurgery in the latest Gamma Knife model. For beginners, there is valuable information related to imaging, quality assurance, patient care, anesthesia, and regulatory requirements. Advance users will appreciate the summary of the long-term outcome of important indications. Additional chapters on cavernous malformation, orbital, uveal, and ocular disorders clarify the role of radiosurgery. This book is a concise overview for physicians interested in radiosurgery. It will be of great value to neurosurgeons, radiation oncologists, and medical physicists concerned with learning about the indications of radiosurgery.
'The book is compact and well presented and can certainly be recommended for the departmental library.'
Because of the huge clinical experience that has been accumulated in radiosurgery, it seems timely to explore and process out systematically pathological fundamentals on the effect of focused irradiation. The better understanding of radiobiology will enhance the outcomes of radiosurgical procedures. Renowned experts from all over the world discuss the baselines of pathology and radiobiology, medical physical principles, dose prescription guidelines, current radiosurgical techniques, advanced computer technology and recent imaging methods in radiosurgery. In this unique volume the most pioneering feature is the parallel discussion of clinical radiosurgical results with fundamental pathologica...
This textbook aims to examine some of the most controversial areas of neurological surgery by applying the current evidence to illuminate our understanding of the pathophysiology of each disease and the outcomes from surgical and non-surgical treatments. The Evidence for Neurosurgery is a textbook that will challenge current dogmas in many instances, provide an organized framework for understanding where current evidence can be applied clinically, and illustrate where gaps in the evidence exist and how these deficiencies may be filled in the future. In the first chapter, "Clinical Evidence", the reader will gain an understanding of the levels of clinical evidence and will learn what types of study designs are appropriate and in which situations. The textbook is then divided into six sections: Spine, Vascular, Tumor, Pediatrics, Functional, and Trauma.
In this third edition of Intracranial Stereotactic Radiosurgery, Drs. Sheehan and Lunsford provide an updated assessment of the practice of stereotactic radiosurgery. Topics include benign and malignant tumors, cerebrovascular abnormalities, and functional disorders. Several new topics are now included and focus on immunotherapy, hypofractionation, and repeat radiosurgery. Each chapter contains key figures and tables to illustrate the critical concepts of the work. Contributors to the book represent many of the most prestigious stereotactic radiosurgery centers across the world. This book is comprised of 36 chapters and represents a comprehensive update to prior editions. It is intended to b...
The molecular era ushered in the cloning of the growth hormone (GH) gene and the production of unlimited amounts of GH through recombinant technology. The continuing momentum of research from basic science to clinical evaluation has brought unprecedented advances to the understanding of GH biology for the clinical endocrinologist. Growth Hormone Related Diseases and Therapy: A Molecular and Physiological Perspective for the Clinician distills all the new information of relevance to the endocrinologist over the last 20 years by offering five sections: physiology, molecular genetics, GH deficiency, acromegaly and pharmacotherapy. The first section on physiology focuses on GH action. A review o...
Acoustic neuroma outcomes have been greatly improved by advances in microsurgical techniques, and recently by the long-term application of radiosurgery, which has proven to be an appropriate, verifiable, and extremely clinically relevant treatment strategy. This volume brings together the latest opinions of outstanding physicians and surgeons who treat patients with acoustic neuromas, commonly known as vestibular neuromas. Since the days of Cushing, when partial tumor removal seemed the best method for saving a patient's life, the management of this relatively rare tumor has sparked enormous clinical interest. The book outlines the various stages in the evolution of vestibular schwannoma sur...
An excellent summary of more than 30 years of accumulated experience Clinical outcomes of brain vascular malformation have been greatly improved by advances in microsurgery, endovascular techniques and stereotactic radiosurgery. Radiosurgery has proven to be the least invasive technique and is associated with documented long-term success. The papers in this volume present the experience of leading brain vascular malformation specialists who describe the outcome of radiosurgery for arteriovenous malformations, cavernous malformations and dural arteriovenous fistulas. These reviews expand the knowledge of the role of stereotactic radiosurgery alone or in combination with other treatment modali...
This issue of the Neurosurgery Clinics, Guest Edited by Drs. Jian, Ames, and Shaffrey, presents updates and state-of-the-art approaches to spinal deformity surgery. Spine surgery is a timely topics amongst neurosurgeons, and one that is continually evolving. Articles in this issue include Radiographic and Clinical Evaluation of Adult Spinal Deformity; Use of Surgimap in Osteotomy Planning, Correction Calculation, and Reciprocal Changes; Adolescent Scoliosis Classification and Treatment; Osteotomy for Rigid Deformity; Coronal Realignment, Reduction Techniques, and Complication Avoidance; Cervical Deformity; High Grade Sponylolisthesis; Proximal Junctional Kyphosis; and The Role of Minimally Invasive Techniques in the Treatment of Adult Spinal Deformity.
Clinical information for Otolaryngologists is provided in topics that include: Natural History (including histology, epidemiology, etc.); Clinical and Diagnostic Evaluation (including cost effectiveness of imaging vs audiometry); Neurophysiological Correlates: Preoperative, Intraoperative and Postoperative - Facial nerve; Neurofibromatosis Type 2 and Genetics; The Art of Management Decision Making: From Intuition to Evidence Based Medicine (including analysis of various decision making strategies); Radiation Therapy and Radiosurgery: Indications, Techniques and Results (CK, GK, LINAC,etc...); Management of Radiation/Radiosurgical complications and failures; Retrosigmoid Approach: Indications...