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The Claustrum: charting a way forward for the brain’s most mysterious nucleus
  • Language: en
  • Pages: 143

The Claustrum: charting a way forward for the brain’s most mysterious nucleus

The claustrum is a long, band-like grey matter structure situated in the ventrolateral telencephalon of most, if not all, mammalian brains. Due to its shape and close proximity to white matter structures and insular cortex, the anatomy and behavioral relevance of the claustrum have proven difficult to study. As a result, disagreements in the literature exist over ontogeny, phylogeny, anatomical boundaries, and connectivity. Despite this, it is generally regarded that the claustrum contains excitatory projection neurons that reciprocally connect to most regions of the cerebral cortex, a feature that has fostered varying hypotheses as to its function. These hypotheses propose multisensory integration, coordination of cortical activity for the generation of conscious percepts, or saliency filtration. The articles of this e-book consider the historical and recent highlights in claustrum structure, hodology, and function and seek to provide a compelling way forward for this “hidden” nucleus.

Experimental models of early exposure to alcohol: a way to unravel the neurobiology of mental retardation
  • Language: en
  • Pages: 105

Experimental models of early exposure to alcohol: a way to unravel the neurobiology of mental retardation

Excessive alcohol drinking represents a major social and public health problem for several countries. Alcohol abuse during pregnancy leads to a complex syndrome referred to as fetal alcohol spectrum disorders (FASD), chiefly characterized by mental retardation. The effects of early exposure to ethanol can be reproduced in laboratory animals and this helped to answer several key questions concerning the human pathology. The interest of experimental models of FASD is twofold. First, they increase our knowledge about the dose and modality of alcohol consumption able to induce damaging effects on the developing brain. Second, experimental models of FASD can provide useful hints to elucidate the ...

Sailing Across a Wounded Sea
  • Language: en
  • Pages: 272

Sailing Across a Wounded Sea

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Permutation Tests for Complex Data
  • Language: en
  • Pages: 448

Permutation Tests for Complex Data

Complex multivariate testing problems are frequently encountered in many scientific disciplines, such as engineering, medicine and the social sciences. As a result, modern statistics needs permutation testing for complex data with low sample size and many variables, especially in observational studies. The Authors give a general overview on permutation tests with a focus on recent theoretical advances within univariate and multivariate complex permutation testing problems, this book brings the reader completely up to date with today’s current thinking. Key Features: Examines the most up-to-date methodologies of univariate and multivariate permutation testing. Includes extensive software co...

Muscle: The Gripping Story of Strength and Movement
  • Language: en
  • Pages: 214

Muscle: The Gripping Story of Strength and Movement

“Filled with illustrations, illuminating stories, and historical deep dives, Muscle will give you new insight into the power of our bodies.” —Milan Polk, Men’s Health An entertaining illustrated deep dive into muscle, from the discovery of human anatomy to the latest science of strength training. Muscle tissue powers every heartbeat, blink, jog, jump, and goosebump. It is the force behind the most critical bodily functions, including digestion and childbirth, as well as extreme feats of athleticism. We can mold our muscles with exercise and observe the results. In this lively, lucid book, orthopedic surgeon Roy A. Meals takes us on a wide-ranging journey through anatomy, biology, his...

Adult Neurogenesis: Beyond Rats and Mice
  • Language: en
  • Pages: 238

Adult Neurogenesis: Beyond Rats and Mice

Researchers working on adult neurogenesis have focused largely on inbred laboratory rodents. While this provides a strong advantage of restricting genetic variation in the group, it also narrows our perspective on adult neurogenesis as a biological phenomenon. Many unsolved issues and open questions cannot be resolved without the contribution of comparative studies spanning through widely different species: how did adult neurogenesis evolve, what is the link between adult neurogenesis and brain complexity, how do adult neurogenesis and animal behavior influence each other, how does adult neurogenesis contribute to brain plasticity, cognition and, possibly, repair, and how do experimental conditions affect adult neurogenesis. The main message from the comparative approach to adult neurogenesis is that the relative exclusive focus on laboratory rodents can result in a bias on how we think about this biological process.

Coping With Extreme Environments: A Physiological/Psychological Approach
  • Language: en
  • Pages: 229

Coping With Extreme Environments: A Physiological/Psychological Approach

Understanding how humans cope in extreme environments has expanded our knowledge of the physiological and psychological challenges involved and helped us to quit our comfortable paradigms built on “steady states”. Furthermore, measuring our reactions to intermittent stressors and determining the oscillations of our coping mechanisms has led us to unexpected understandings. This methodology has also directly improved our translational or multidisciplinary approach to the subject. Studying healthy individuals in extreme environments could improve our understanding of patients with impaired physiological capacities (who are coping with an environment that becomes extreme to them) and also improve our understanding of physiology and psychology in the elderly.This eBook collects articles that address this translational multidisciplinary approach in an integrative way. As a whole, this Research Topic aims to better understand human/animal physiology and psychology.

The Physiology of Dolphins
  • Language: en
  • Pages: 304

The Physiology of Dolphins

  • Type: Book
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  • Published: 2023-11-25
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  • Publisher: Elsevier

The Physiology of Dolphins explains complex physiological problems of dolphins that are largely driven by technological developments of biologging tools. The book provides a collection of review chapters from leaders in the field of dolphin ecophysiology, making it essential for instructors, researchers and graduate students interested in the physiological and anatomical adaptations that make life possible for this charismatic marine mammal. Sections cover the complete physiology of the mammal and include information on the current threats for dolphins and whales from environmental pressures such as climate change, overfishing, pollution and our increasing human presence in the ocean. This i...

Melatonin
  • Language: en
  • Pages: 561

Melatonin

  • Type: Book
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  • Published: 2020-10-28
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  • Publisher: CRC Press

Melatonin: Biosynthesis, Physiological Effects, and Clinical Applications provides a thorough review of recent advances in major areas of melatonin research. The book is arranged in a logical sequence, beginning with the history of melatonin and then proceeding to cover its biochemistry and secretion, physiological effects, and clinical significance. New findings and current concepts are emphasized, and a significant amount of previously unpublished data are included. The book will be an important reference for neurobiologists, cell biologists, ophthalmologists, endocrinologists, neuroendocrinologists, reproductive biologists, psychiatrists, and other researchers and clinicians interested in melatonin.

Emerging Infectious Diseases
  • Language: en
  • Pages: 1114

Emerging Infectious Diseases

  • Type: Book
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  • Published: 2017
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  • Publisher: Unknown

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