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Reports up-to-date research developments on purifying and isolation large organic molecules. The text provides information on high-performance liquid chromatography and capillary electrophoresis (CE) as tools for analyzing biomacromolecules and developing new biochemical and medicinal compounds. It applies biochemical separation technology to the study of macromolecules such as proteins, polysaccharides, nucleic acids and more.
A good portion of this book has been devoted to the copper-dependent enzymes, these being the more numerous. The chapter dealing with serum amine oxidases also focuses attention on their catalytic mechanism, as these enzymes have been studied in greater depth.As the presentation of topics whose experimental basis is rapidly developing is likely to stimulate the reader‘s interest, many bibliographic references have been included.Readers could find this book poor, as far as many topics are dealt with in a relatively little space, but we believe it essential to trace the background of our present knowledge in the field of amine oxidases, stressing the future outlook of research on these enzymes, for they are becoming more and more important in general and medical biochemistry.
First multi-year cumulation covers six years: 1965-70.
Research on historical processes such as commercialisation traditionally concentrated on the motors of change and measurement of their impact, and considered the labouring classes as the passive objects of such changes. Developments in the social sciences in recent years have stimulated a new reading of the historical sources in terms of the social relations and strategies of families in interpreting and adapting to their own use institutional settings and economic resources. The essays presented in this 1991 book explore the relationship between the historical experiences of social relations and the demands and opportunities offered by the economy in early modern Europe through a focus on the strategies of labouring families. Critical discussion of the historian's use of sources characterises the essays, which provide case-studies of social groups in north-central Italy and the French Alps. They relate to three specific themes: the exploitation of non-agricultural resources in the countryside, urban guilds and charitable provision.