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Pediatric cancer develops in 1 to 500 children. Typically, the type of cancers that develop in children is different than those that develop in adults, in that they are often the result of a DNA mutation rather than environmental or lifestyle risk factors. Leukemia, brain and central nervous system tumors, and neuroblastomas are the most common cancer types in child populations. Children tend to respond better to anticancer treatments, including chemotherapy and radiation. However, long-term side effects are common in children, often requiring follow-up care and lifestyle intervention for the rest of their lives. The percentage of 5-year survivors was over 50% for the most common cancers. This suggests that a majority of cancers in this population are highly survivable. As such, research should focus on aspects of survivorship for these individuals. This book will explore issues related to pediatric cancer and their associated treatments.
Minimally invasive techniques, designed to reduce morbidity and risk while simultaneously improving outcomes, are increasingly being used in oral and maxillofacial surgery. This book covers the most recent technological developments and the advanced techniques used when performing such minimally invasive surgery in patients with common and rare oral and maxillofacial pathologies. The relevant basic science is reviewed, but the principal focus is on the surgical techniques themselves. These are described step by step with the aid of numerous superb color illustrations that will help the clinician to gain a full understanding of the technology and the procedures. In addition, still emerging techniques of endoscopy, navigation, and minimally invasive surgery are well covered. This text will be a premier resource for physicians who diagnose and treat oral and maxillofacial pathologies and injuries.
The world is wrought with risks that may harm people and cost lives. The news is riddled with reports of natural disasters (wildfires, floods, earthquakes, hurricanes), industrial disasters (chemical spills, water and air pollution), and health pandemics (e.g., SARS, H1NI, COVID19). Effective risk communication is critical to mitigating harms. The body of research in this handbook reveals the challenges of communicating such messages, affirms the need for dialogue, embraces the role of instruction in proactively communicating risk, acknowledges the function of competing risk messages, investigates the growing influence of new media, and constantly reconsiders the ethical imperative for communicating recommendations for enhanced safety.
Samson/Daft/ Donnet's Fundamentals of Management is a robust foundation text providing a balance of broad, theoretical content with accessible language for students. This sixth edition features a new author on the team and contains updates to content based on recent research. Along with current management theory and practice, the text integrates coverage of innovation, entrepreneurship, agile workplaces, social media and new technology throughout. The book is rich with experiential exercises, self-assessment activities, challenges and cases for students to engage with, developing multiple skills. Examples within the text are both local and global, with a new focus on a 'skills approach', and each part of the text concludes with a contemporary continuing case study, focussing on car company, Toyota, as it faces managerial challenges and opportunities in the region The text covers the four key management functions: Planning, Organising, Leading, and Controlling, conveying to students the elements of a manager's working day.
This book contains an interesting and state-of the art collection of papers on the recent progress in Human-Computer System Interaction (H-CSI). It contributes the profound description of the actual status of the H-CSI field and also provides a solid base for further development and research in the discussed area. The contents of the book are divided into the following parts: I. General human-system interaction problems; II. Health monitoring and disabled people helping systems and III. Various information processing systems. This book is intended for a wide audience of readers who are not necessarily experts in computer science, machine learning or knowledge engineering, but are interested in Human-Computer Systems Interaction. The level of particular papers and specific spreading-out into particular parts is a reason why this volume makes fascinating reading. This gives the reader a much deeper insight than he/she might glean from research papers or talks at conferences. It touches on all deep issues that currently preoccupy the entire field of H-CSI.
This volume addresses the situation of water and wastewater management from a global angle, underpinned by selected case studies. Without doubt, water and wastewater management are among the greatest challenges of our century, and there is also no doubt that the challenges posed by climate change will become even greater. However, most efforts, especially in developing countries but also in the so-called developed countries, have been less than optimal or not optimal at all. In particular, there are still too many people who have to live without clean water and decent sanitation. Today, 2.2 billion people lack access to safely managed drinking water and wastewater, and 4.2 billion people lack safely managed sanitation services. The question, why this is so and why in many cases in developing countries, is discussed in this book among other urgent water and wastewater management issues. The publication of this book is the start of a book series that in more detail critically reviews, discusses, and analyzes the water and wastewater situation and management in different regions and countries worldwide.
The current paradigm-changing ancient DNA revolution is offering unparalleled insights into central problems within archaeology relating to the movement of populations and individuals, patterns of descent, relationships and aspects of identity – at many scales and of many different kinds. The impact of recent ancient DNA results can be seen particularly clearly in studies of the European Neolithic, the subject of contributions presented in this volume. We now have new evidence for the movement and mixture of people at the start of the Neolithic, as farming spread from the east, and at its end, when the first metals as well as novel styles of pottery and burial practices arrived in the Chal...
This book provides the latest updates on the major challenges of bridging large bone defects, where options range from autografts, “tissue engineered bone”, biomaterials (hydroxyapatite, polycaprolactone and third generation biomaterials) to prostheses. Emphasis has been made on bone tissue engineering, the current state-of-the-art in this field, problems encountered with cell culture technology, scaffolds and bone growth factors (including genomics) and the use of gene therapy for the application of bone growth factors. Attention has also been given to the use of bone autografts. It also covers the use of biomaterials and prostheses as other options for reconstruction. Clinical applications, in addition to the basic science, are also included throughout the discussions.