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Comprehensive Organic Synthesis
The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic sy...
Allele Mining for Genomic Designing of Grain Legume Crops
This book deliberates on the concept, strategies, tools, and techniques of allele mining in grain legume crops and its application potential in genome elucidation and improvement, including studying allele evolution, discovery of superior alleles, discerning new haplotypes, assessment of intra- and interspecific similarity, and also studies of gene expression and gene prediction. Available gene pools in global germplasm collections specifically consisting of wild allied species and local landraces for almost all major crops have facilitated allele mining. Development of advanced genomic techniques, including PCR-based allele priming and EcoTILLING-based allele mining, is being widely used no...
Verified Software: Theories, Tools, Experiments
A Step Towards Verified Software Worries about the reliability of software are as old as software itself; techniques for allaying these worries predate even James King’s 1969 thesis on “A program verifier. ” What gives the whole topic a new urgency is the conjunction of three phenomena: the blitz-like spread of software-rich systems to control ever more facets of our world and our lives; our growing impatience with deficiencies; and the development—proceeding more slowly, alas, than the other two trends—of techniques to ensure and verify software quality. In 2002 Tony Hoare, one of the most distinguished contributors to these advances over the past four decades, came to the conclus...
Liquid Biopsy in Cancer Patients
This text is designed to provide readers with a useful and comprehensive resource and state-of-the-art overview about the new, growing and fast-expanding field of “liquid biopsy” for the management of cancer patients. The liquid biopsy represents an important turning point in oncology since it provides a tool for a serial monitoring of disease. Liquid biopsy is our “hand lens” to follow molecular changes that characterize tumor development and progression. The book provide a unique and valuable resource on the clinical relevance of liquid biopsy as well as on the technical aspects of liquid biopsy analysis. All invited authors are recognized experts in their field. Liquid Biopsy in Cancer Patients: The Hand Lens for Tumor Evolution is targeted to resident and fellows physicians, medical oncologists, molecular biologists and biotechnologists.
Pulmonary Hypertension
This book provides the framework for a singular reference in the field of pulmonary hypertension. Pulmonary vascular disease is a complex and heterogeneous condition characterized by remodeling of distal pulmonary arterioles that increases pulmonary vascular resistance to affect cardiopulmonary hemodynamic and right ventricular function adversely, resulting in a clinical syndrome of diminished exercise tolerance, shortness of breath, and heart failure-associated morbidity and mortality. Owing to the availability of novel pulmonary circulation-selective pharmacotherapies over the previous decade, the number of pulmonary hypertension patients eligible for treatment has increased substantially....
General Knowledge July 2017 eBook
General Knowledge eBook (July 2017) has been structured in such a way that it fulfills the needs of the aspirants preparing for UPSC, State Services, SSC, Banking, Railway, NDA etc. This edition includes Indian Economy, Indian Polity & Governance, History, Environment & Ecology, Geography (India & World), Science & Technology, State at a Glance, One liner Facts, Discussion and analysis of the current GK topics and MCQs for further practice. All the topics are presented with facts and brief description, so that the reader gets full knowledge and understanding in all the key areas of exams. Some maps, tables, etc are also included for further clarity.
Public Health Perspectives on Depressive Disorders
How does mental health impact public health? In 2001, the WHO recognized depressive disorders as the leading cause of disability worldwide. But most Americans who meet diagnostic criteria for major depression are untreated or undertreated. Luckily, recent advances have finally made it possible for the field of public health to address mental health in the population. Public Health Perspectives on Depressive Disorders fills a gap by identifying the tools and strategies of public health practice and by exploring their application to twenty-first-century public mental health policy and practice. By looking at depressive disorders through a public health lens, this book highlights the centrality...
