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Considered the definitive source in its field for over 35 years, Endocrinology: Adult and Pediatric, has been thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology. Unique perspectives from a team of trusted, world-renowned experts ensure this medical reference book remains the most highly-regarded text in the field. Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information quickly, while still getting the complete coverage you expect. Now in full color, with sp...
Efficient mobile systems that allow for vital sign monitoring and disease diagnosis at the point of care can help combat issues such as rising healthcare costs, treatment delays in remote and resource-poor areas, and the global shortage of skilled medical personnel. Covering everything from sensors, systems, and software to integration, usability, and regulatory challenges, Mobile Point-of-Care Monitors and Diagnostic Device Design offers valuable insight into state-of-the-art technologies, research, and methods for designing personal diagnostic and ambulatory healthcare devices. Presenting the combined expertise of contributors from various fields, this multidisciplinary text: Gives an over...
The disorders induced by iodine deficiency affect at least one billion people. Because ofits effects on brain development, iodinedeficiency is the single most preventable cause of mental retardation in the world. Therefore, the United Nations and the Heads of State of almost all the world's countries represented at the Summit for Children in 1990 adopted resolutions to eradicate the disorders induced by iodine deficiency (IDD) by the year 2000. For geological and socio-economic reasons, most of the populations affected by iodine deficiency disorders live in isolated and usually mountainous areas, in pre industrialized parts ofthe world. The problem of iodine deficiency in Europe has been gre...
More than a collection of review articles, G Proteins, Receptors, and Disease summarizes in depth the state of our knowledge today concerning not only how cells communicate via G-protein-coupled signal transduction processes, but also how defects in these proteins and their receptors can cause serious human disease involving many different organ systems. Written by leading investigators, each chapter describes in detail the structure and function of a particular G protein or receptor, outlines possible mutations, and discusses fully the molecular pathogenesis of associated diseases. Diagnostic and therapeutic implications are also discussed when relevant. In its unique blend of cutting-edge basic science and clinical medicine, G Proteins, Receptors, and Disease offers deep insights into the physiological significance of this key signal transduction pathway, as well as into the molecular basis of diseases ranging from obesity to malignancy. The basic understanding of the complex signal transduction process achieved here provides a firm foundation for future efforts to prevent and cure these diseases.
The considerable increase in the incidence of thyroid cancer in children in areas exposed to the fallout from the Chernobyl nuclear reactor accident has drawn attention to the need for a better understanding of the relationship between radiation exposure (especially from the radionuclides of iodine) and the risk of thyroid cancer. An increase in thyroid cancer has been reported both in patients exposed to therapeutic and diagnostic external radiation, and in the population exposed to radiation from the Hiroshima and Nagasaki atomic bombs. While there is no evidence of a significant increase of this cancer in patients treated with radioactive iodine, an increase in thyroid cancer incidence wa...
Prominent international researchers contributed to this volume of reports advancing the study of brain function and morphology. Comprising investigations in several areas of neuroscience, the book includes research in neurodegenerative diseases and in neuroregeneration in adults. Described here are the effects of neuropeptides and biogenic amines on feeding, respiration, and other autonomic functions as well as on behavior. One chapter focuses on regulation of the blood brain barrier function by various neuropeptides, proteins, receptors, and transporters. Another is concerned with the modulation of higher brain functions by neuropeptides and biogenic monoamines. Yet another chapter presents research on ischemic neuronal damage and hippocampal neurogenesis in the adult mouse. Morphological or physiological techniques to study neuropeptides and neuromodulators influencing higher-order or brain-stem functions are given particular attention. The use of bio-imaging tools such as brain navigation systems and fMRIs with patients in a clinical setting creates new possibilities for investigation of human brain function and specialization of treatment.
This book features recent research in mathematical modeling of indirectly and directly transmitted infectious diseases in humans, animals, and plants. It compiles nine not previously published studies that illustrate the dynamic spread of infectious diseases, offering a broad range of models to enrich understanding. It demonstrates the capability of mathematical modeling to capture disease spread and interaction dynamics as well as the complicating factors of various evolutionary processes. In addition, it presents applications to real-world disease control by commenting on key parameters and dominant pathways related to transmission. While aimed at early-graduate level students, the book can also provide insights to established researchers in that it presents a survey of current topics and methodologies in a constantly evolving field.
ACKNOWLEDGEMENTS PART 1 FISH CONSUMPTION AND METHYLMERCURY EXPOSURE IN THE AMAZON A. C. BARBOSA, A. M. GARCIA, J. R. DESOUZAI Mercurycontamination inhairofriverine 1-8 populations of Apiacas Reserve in the Brazilian Amazon E. D. BIDONE, Z. C. CASTILHOS, T. J. S. SANTOS, T. M. C. SOUZA and L. D. LACERDA I Fish contamination and human exposure to mercury in Tartarugalzinho River, Amapa State, Northern Amazon, Brazil. A screening approach 9-15 H. A. KEHRIG, O. MALM and H. AKAGI I Methylmercury in hair samples from different riverine groups, Amazon, Brazil 17-29 J. LEBEL, M. ROULET, D. MERGLER, M. LUCOTTE and F. LARRIBE I Fish diet and 31-44 mercury exposure in a riparian Amazonian population O....