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Regenerative Medicine and Cell Therapy
Most human tissues do not regenerate spontaneously. Cell therapy and tissue engineering, which involve collecting cells from either the patient or a donor and introducing them into injured tissues or organs, sometimes after modifying their properties, offer promising solutions for regenerative medicine. Indeed, so promising are these therapies that current research has shifted from organ growth to cell therapy. The range of therapeutic applications is wide, including cardiac insufficiency, atherosclerosis, cartilage defects, bone repair, burns, diabetes and liver or bladder regeneration.This book, whilst not covering all aspects
Exercise Physiology
There is no doubt that if the field of exercise physiology is to make further advancements, the various specialized areas must work together in solving the unique and difficult problems of understanding how exercise is initiated, maintained and regulated at many functional levels, and what causes us to quit. Exercise is perhaps the most complex of physiological functions, requiring the coordinated, integrated activation of essentially every cell, tissue and organ in the body. Such activation is known to take place at all levels - from molecular to systemic. Focusing on important issues addressed at cellular and systemic levels, this handbook presents state-of-the-art research in the field of...
Neuroelectrodynamics
The essence of brain function consists in how information is processed, transferred and stored. Current neurophysiological doctrine remains focused within a spike timing paradigm, but this has a limited capacity for advancing the understanding of how the brain works. This book puts forward a new model; the neuroelectrodynamic model (NED), which describes the intrinsic computational processes by the dynamics and interaction of charges. It uses established laws of physics, such as those of classical mechanics, thermodynamics and quantum physics, as the guiding principle to develop a general theoretical construct of the brain s computational model, which incorporates the neurobiology of the cel...
Mechanobiology
This book covers the proceedings of the Fifth Symposium on Mechanobiology of Cartilage and Chondrocyte. Mechanobiology can be now considered as a vigorous branch of biomechanics, biorheology and physiology mainly concerned with the study of the influence of mechanical forces on cells and tissues and their clinical or therapeutical applications. As we are now in the age of proteomics, genomics and cell micro mechanical approaches, suing methods like laser tweezers or confocal microscopy, mechanobiology brings new challenges. With such new research, mechanobiology promises new diagnostic and therapeutic approaches. In other respect there has been increasing interest over recent years in the fundamental role played by local mechanical parameters in chondrocyte regulations and cartilage dysfunctions as a first step in the development of osteoarthritis. These proceedings are sub-divided into four parts: Theoretical approaches and mechanobiology of chondrocyte; Cartilage and chondrocyte studies; Osteoarthritis: inflammation degradation and clinical approaches; and, Cartilage engineering
Utopia's Garden
The royal Parisian botanical garden, the Jardin du Roi, was a jewel in the crown of the French Old Regime, praised by both rulers and scientific practitioners. Yet unlike many such institutions, the Jardin not only survived the French Revolution but by 1800 had become the world's leading public establishment of natural history: the Muséum d'Histoire Naturelle. E. C. Spary traces the scientific, administrative, and political strategies that enabled the foundation of the Muséum, arguing that agriculture and animal breeding rank alongside classification and collections in explaining why natural history was important for French rulers. But the Muséum's success was also a consequence of its employees' Revolutionary rhetoric: by displaying the natural order, they suggested, the institution could assist in fashioning a self-educating, self-policing Republican people. Natural history was presented as an indispensable source of national prosperity and individual virtue. Spary's fascinating account opens a new chapter in the history of France, science, and the Enlightenment.
Stem Cells and Regenerative Medicine
As the world’s population ages, the problem of degenerative disease is increasing. At the same time, the demand for organ transplants to repair or replace damaged tissue continues to grow. Regenerative medicine is a branch of translational medicine which promotes the repair, regeneration, or construction of tissues and organs or improves or restores their function through tissue engineering, cell biology, molecular biology and other techniques. Stem cells are one of the most important types of cells used in regenerative medicine, and stem cell research is also one of the most active research areas in the field. This book presents 20 full papers from the 8th International Symposium China-Eu...
'A Cheap, Safe and Natural Medicine'
John Wesley’s Primitive Physic (1747) achieved twenty-three editions in his lifetime, ensuring its popular – and controversial – status in eighteenth-century medicine. This is the first full-length study to examine the theological, intellectual and cultural background to one of the period’s most successful medical texts. By exploring Wesley’s work in the context of his theology, ‘A Cheap, Safe and Natural Medicine’ extends the on-going reconfiguration of the relationship between religion and medicine. Wesley was on a theological mission to recover the primitive purity of the first Christians. Yet the remedies contained within Primitive Physic suggest a pragmatic thinker, whose ...
Pathologies of Travel
The essays collected here not only contribute to our understanding of the conception and application of a variety of medical ideas, showing how they depended on beliefs about climate and corporeal constitution as well as often inconsistent data or récits culled from travellers and geographically dispersed case histories, but also open up illuminatingly complex perspectives on the uncertainties and dangers of the phenomenon of modern travel.
