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Papers in this book report on a wide variety of multicomputer applications, systems and architectures. They all have one aspect on common which is message passing multiprocessors. It includes research presentations of the T9000, TI C-40 and T8/i860-based multicomputers.
The broadening of interest in parallel computing and transputers is reflected this book. Topics discussed include: concurrent programming; graphics and image processing; parallel applications; robotics; and control and software tools. The book also features a collection of abstracts of poster presentations.
Over the last decade, considerable progress has been made in understanding cellular and molecular mechanisms involved in gastrointestinal mucosal injury and repair. These findings provide the basis to identify the etiology and pathogenesis of various gut mucosal injury-related diseases and to develop new therapeutic approaches. The publication at hand is divided into three sections: Epithelial restitution, mucosal repair and ulcer healing, and experimental therapeutics. The first part highlights the early rapid mucosal restitution, focussing on the roles of extracellular matrix, cytoskeleton, cytokines, Ca2+ signaling, polyamines, and the protein kinase C/DAG pathways. The next section deals...
Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design. Drug Discovery features chapters written by an international team of pharmaceutical and medicinal chemists. Contribut...
Scale modeling can play an important role in R&D. When engineers receive some ideas in new product development, they can test how the new design looks by bui- ing scale models and they can get an actual feeling with the prototype through their imagination. Professor Emori often said: “When children play with a toy airplane, their mind is wondering about the prototype airplane which they haven’t ridden. ” Children can use the scale model airplane as a means to enter into an imagi- tive world of wonder by testing in their own way how the actual airplane might function, how the actual airplane can maneuver aerodynamically, what might be the actual sound of a jet engine, how to safely land...
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
This volume is a comprehensive collection of extended contributions from the fourth international symposium on Modeling and Implementing Complex Systems (MICS’2106) organized into four main topics: Networking and Cloud Computing, Software Engineering and Formal Methods, Intelligent and Information Systems, and Algorithms and Complexity. This book presents recent advances related to theory and applications of networking and distributed computing, including: cloud computing, software engineering, formal methods, information extraction, optimization algorithms, intelligent systems, and multi-agent systems.
Therapeutic applications within regenerative biomedicine has gained tremendous interest from a growing, multidisciplinary community of investigators in recent years, driven by the hope of finding cures for several diseases. Regenerative Medicine and Cell Therapy discusses cutting-edge science in the field of regenerative biomedicine and its therapeutic applications to various medical disorders. The chapters are written by renowned scientists in the specific fields. This will be a useful book for basic and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors’ goal is that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.
After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.