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In recent years, progress in pain research has yielded substantial new insights, and this has profoundly altered our understanding of various orofacial pain conditions. Written by renowned international researchers and clinicians, this state-of-the-art textbook presents recent advances in the understanding of orofacial pain and offers evidence-based management approaches, thus bridging the gap between timely research findings and daily clinical practice. The reader is provided with helpful in-depth information of up-to-date advances in basic research as well as with the present knowledge of the pathophysiology, diagnosis and management of the five most common orofacial pain conditions. In addition, the psychosocial impact of orofacial pain in daily life and future developments are presented. Health care professionals, such as dentists, neurologists, physicians as well as students will find this volume helpful and valuable for an advanced understanding of the diverse orofacial pain conditions and for the improvement of patient care.
Covering the latest advances in the use of plants to produce medicinal drugs and vaccines, examines topics including plant tissue culture, secondary metabolite production, metabolomics and metabolic engineering, bioinformatics, molecular farming and future biotechnological directions.
Autism is not a single disease but a syndrome of different diseases. In this completely reworked and updated third edition, two world authorities, Christopher Gillberg and Mary Coleman, address the difficulties this presents for clinical diagnosis with diagnostic aids and clear guidelines for medical evaluation. Epidemiology, neuropsychological studies and behavior complexes, such as self-injury, are reviewed in detail, and the authors give a detailed explanation of what is known about the molecular biology and genetics of autism. Epilepsy and electrophysiological studies are also covered, as well as biochemistry, endocrinology, immunology, brain imaging and neuropathology. The available medical therapies are reviewed, along with an update on what is known about other interventions, such as psychoeducational and behavioral modification procedures. The book concludes with an integration of current knowledge from diverse fields. This is an essential text for clinicians and will also be of interest to parents of autistic children.
This is the second of a series of four volumes that are intended to present a complete corpus of all the church buildings, of both the western and the oriental rites, rebuilt or simply in use in the Crusader Kingdom of Jerusalem between the capture of Jerusalem for the First Crusade in 1099 and the loss of Acre in 1291. This volume completes the general topographical coverage begun in volume I, and will be followed by a third volume dealing specifically with the major cities of Jerusalem, Acre and Tyre (which are excluded from the preceding volumes). The project, of which this series represents the final, definitive publication, has been sponsored by the British School of Archaeology in Jerusalem. On completion the corpus will contain a topographical listing of all the 400 or more church buildings of the Kingdom that are attested by documentary or surviving archaeological evidence, and individual descriptions and discussion of them in terms of their identification, building history and architecture. Some of the buildings have been published before, but many others are published here for the first time.