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Hyperbole and a Half
#1 New York Times Bestseller “Funny and smart as hell” (Bill Gates), Allie Brosh’s Hyperbole and a Half showcases her unique voice, leaping wit, and her ability to capture complex emotions with deceptively simple illustrations. FROM THE PUBLISHER: Every time Allie Brosh posts something new on her hugely popular blog Hyperbole and a Half the internet rejoices. This full-color, beautifully illustrated edition features more than fifty percent new content, with ten never-before-seen essays and one wholly revised and expanded piece as well as classics from the website like, “The God of Cake,” “Dogs Don’t Understand Basic Concepts Like Moving,” and her astonishing, “Adventures in...
Pruritus
This book provides a thorough and comprehensive reference in the management of pruritus, designed to be a convenient resource for all physicians confronted with patients suffering from itch. The Editors have recruited a board of internationally renowned experts to provide an in-depth analysis of the causes and management of pruritus, including the current concepts in pathophysiology and novel therapeutics. Acute and chronic pruritus can represent significant management issues both as a common physiological sensation and as a manifestation of dermatologic and non-dermatologic diseases. All patients suffering from itch know that it is a very awkward sensation. Unfortunately, this often significant symptom is frequently considered less severe in comparison with pain. The consequences are that research on this field has been poorer than research on pain and that pruritus is therefore more difficult to treat. Pruritus, Second edition addresses the new concepts and discoveries that have modified our understanding of this condition. It explains the pathophysiology of itch, describes all causes, and provides guidelines for management and treatment.
Frontiers in Hypertension Research
reached full definition in the 1940s by Kempner diet. The important role of adrenal aldosterone and associates in demonstrating the beneficial ef secretion in supporting human hypertension is now fects of a low salt rice diet for treating hypertensive well recognized as are the beneficial effects of patients. It became apparent that the value of rice blockade, especially in low-renin patients who ex was wholly related to its sodium content. A rice hibit inappropriate or absolute excesses of aldoste diet, or any other stringent low sodium diet, rone secretion. Further definition of the more sub greatly improves or completely corrects the hyper tle participation of aldosterone and of the facto...
Hypertensive Cardiovascular Disease: Pathophysiology and Treatment
Hypertension is a major world-wide health problem. With high blood pressure there is a greater risk of stroke, heart attack, heart failure, kidney disease and renal failure. Far too few people realize what the risks are and what can be done to prevent these risks even in the countries where pro grams in hypertension research are active and the full significance of hyper tension is best understood. Some studies of the known hypertensive popu lation indicate that one-half or less are receiving adequate treatment, and, of those on therapy, only half have their high blood pressure satisfactorily controlled. These realizations emphasize the need to inform all segments of society throughout the wo...
Encyclopedia of Food Allergy
Encyclopedia of Food Allergy, organized in 10 sections, with ~200 chapters, and written by world-renowned clinician-scientist authors, is the most comprehensive resource for food allergy ever compiled. With online and physical presence, intuitive and easily accessible organization of information, the reader can quickly access overview and general topics as well as detailed information to inform solutions to clinical or research questions. Research topics provide the necessary background for the novice as well as the details required for those in the field. Clinical topics provide comprehensive and practical information, with generous use of tables, figures, and key points/clinical pearls, to...
Concepts in Hypertension
This is a Festschrift to Professor Sir Stanley Peart, Professor of Medicine at St. Mary's Hospital and Medical School, University of London since 1956, who has influenced and directed many of us in the better understanding of the patho physiological basis and the clinical practice of hypertension. It commemorates, and we hope will preserve, memories of a special occasion when we met to honour him at the Castella de Pomeiro, Como, Italy. At this meeting his "extended family" (pictured above) shared experiences, discussed current scientific and clinical ap proaches in hypertension research and indulged in reminiscences of their exciting times on his Unit at St. Mary's. We particularly hope tha...
Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy
This volume gives the latest developments in on the mechanisms of cancer cell resistance to apoptotic stimuli, which eventually result in cancer progression and metastasis. One of the main challenges in cancer research is to develop new therapies to combat resistant tumors. The development of new effective therapies will be dependent on delineating the biochemical, molecular, and genetic mechanisms that regulate tumor cell resistance to cytotoxic drug-induced apoptosis. These mechanisms should reveal gene products that directly regulate resistance in order to develop new drugs that target these resistance factors and such new drugs may either be selective or common to various cancers. If successful, new drugs may not be toxic and may be used effectively in combination with subtoxic conventional drugs to achieve synergy and to reverse tumor cell resistance. The research developments presented in this book can be translated to produce better clinical responses to resistant tumors.
Polarons in Bulk Materials and Systems with Reduced Dimensionality
Attempts to treat electron-phonon coupled systems, with emphasis on Many Body aspects for dense electron systems, taking into account continuum as well as lattice polaron effects. This work aims to introduce the study of such systems, where strong electron-electron correlations and large electron-phonon coupling strengths play important roles.
