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Featuring the improved format used in the 5th edition, this updated set presents, in logical groupings, comprehensive toxicological data for industrial compounds, including CAS numbers, physical and chemical properties, exposure limits, and biological tolerance values for occupational exposures, making it essential for toxicologists and industrial hygienists. This edition has about 40% new authors who have brought a new and international perspective to interpreting industrial toxicology, and discusses new subjects such as nanotechnology, flavorings and the food industry, reactive chemical control to comprehensive chemical policy, metalworking fluids, and pharmaceuticals.
A collaborative effort in which the three authors address the controversies that arise in the regulation of chemicals that are known or suspected to cause cancer. Annotation copyrighted by Book News, Inc., Portland, OR
Annotation. Contents: Status and Future Prospects of Reactor Neutrinos, Solar Neutrinos, and Supernova Neutrinos; Status and Future Prospects of Long Baseline Neutrino Experiments, Atmospheric Neutrinos; Dark Matter Searches and Double Beta Decays; Lepton Number Violated Muon Decays; Proton Decay Searches; Neutrino Phenomenology and Model Building.
The ever-increasing release of harmful agents due to human activities have led in some areas of the world to heavy pollution. In order to protect human health and the environment, environmental standards that shall limit the release and the concentration of those toxic agents in the environment and hence the exposure to it have to be established. The related assessment and decision-making procedures have to be based on solid scientific data about the effects and mechanisms of these agents as well as on ethical, social and economic aspects. For risk evaluation, the knowledge of the dose response curve is an essential prerequisite. Dose responses without a threshold dose are most critical in t...
Occupational exposure limits exemplify the practical application of moral values in medical science. But are they really effective in protecting workers from chemical hazards? In order to answer this question on the basis of sound empirical evidence, this book presents an unusually detailed and comprehensive analysis of three lists of exposure limits from the United States, Germany and Sweden. Hansson analyzes the nature of toxicological knowledge and discusses how the standards of proof required in a regulatory context differ from those appropriate in pure science. In his view, decision-makers must deal not only with the known risks but also with the uncertainties that arise as a consequence of the incompleteness of toxicological information. With this in mind, he proposes new ways to organize exposure limits and to evaluate toxicological data for regulatory purposes. Setting the Limit is a thorough, detailed study of the application of ethical principles in an important area of public health practice. It is intended for occupational health professionals and risk analysts, as well as philosophers and sociologists of science.
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Statistical Models in Toxicology presents an up-to-date and comprehensive account of mathematical statistics problems that occur in toxicology. This is as an exciting time in toxicology because of the attention given by statisticians to the problem of estimating the human health risk for environmental and occupational exposures. The development of modern statistical techniques with solid mathematical foundations in the 20th century and the advent of modern computers in the latter part of the century gave way to development of many statistical models and methods to describe toxicological processes and attempts to solve the associated problems. Not only have the models enjoyed a high level of ...
This volume contains edited contributions from the speakers at the NATO Advanced Research Workshop on "DNA Repair Mechanisms and Their Biological Implications in Mammalian Cells" held October 1-6, 1988, at the Abbaye Royale de Fontevraud, Fontevraud France. The meeting was dedicated to Paul Howard-Flanders (Yale University, New Haven, CT. , 1919-1988), whose seminal con tributions to the DNA repair field include the cO-discovery of the excision repair pathway, the elucidation of post-repli cation repair in E. coli, the isolation of the lexA and recC mutants, and his extensive work on the enzymology of RecA. A plethora of recent developments in DNA repair mechan isms and related processes in mammalian cells have advanced our understanding of this field in a number of different areas and have given new emphasis to the ways these systems both resemble DNA repair processes in other groups of organisms in some respects yet are strikingly different from them in others. Within the past decade there have been a number of international conferences on DNA damage and repair mechanisms but none has been focused on these processes in mammalian cells.