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Patty's Toxicology, 6 Volume Set
Featuring the improved format used in the 5th edition, this updated set presents, in logical groupings, comprehensive toxicological data for industrial compounds, including CAS numbers, physical and chemical properties, exposure limits, and biological tolerance values for occupational exposures, making it essential for toxicologists and industrial hygienists. This edition has about 40% new authors who have brought a new and international perspective to interpreting industrial toxicology, and discusses new subjects such as nanotechnology, flavorings and the food industry, reactive chemical control to comprehensive chemical policy, metalworking fluids, and pharmaceuticals.
DNA Repair Mechanisms and Their Biological Implications in Mammalian Cells
This volume contains edited contributions from the speakers at the NATO Advanced Research Workshop on "DNA Repair Mechanisms and Their Biological Implications in Mammalian Cells" held October 1-6, 1988, at the Abbaye Royale de Fontevraud, Fontevraud France. The meeting was dedicated to Paul Howard-Flanders (Yale University, New Haven, CT. , 1919-1988), whose seminal con tributions to the DNA repair field include the cO-discovery of the excision repair pathway, the elucidation of post-repli cation repair in E. coli, the isolation of the lexA and recC mutants, and his extensive work on the enzymology of RecA. A plethora of recent developments in DNA repair mechan isms and related processes in mammalian cells have advanced our understanding of this field in a number of different areas and have given new emphasis to the ways these systems both resemble DNA repair processes in other groups of organisms in some respects yet are strikingly different from them in others. Within the past decade there have been a number of international conferences on DNA damage and repair mechanisms but none has been focused on these processes in mammalian cells.
In Search of Safety
A collaborative effort in which the three authors address the controversies that arise in the regulation of chemicals that are known or suspected to cause cancer. Annotation copyrighted by Book News, Inc., Portland, OR
Genetic Toxicology and Cancer Risk Assessment
Presents state-of-the-art regulatory cancer risk assessment models including a biologically based model for two-hit carcinogenesis and cell proliferation! This book comprehensively reviews the various roles of genetic toxicology in human cancer risk assessment conducted by United States and worldwide regulatory agencies-discussing hazard identification, dose-response relationships, exposure assessment, and current practices of risk characterization. Examines predictive values of mutagenicity tests, mechanisms of carcinogenesis, and conventional genotoxicity tests required by the International Conference on Harmonization and the Organization for Economic Cooperation and Development/Environmen...
Toxic Properties of Polymers and Additives
This directory is a comprehensive guide to the toxicity of over 1000 polymers, monomers and additives used by the rubber and plastics industries. Since the toxic properties of materials are determined by the toxic properties of the substance released by them, a significant proportion of the book deals with monomers, plasticisers, stabilisers, and other additives. In this regard, the book will be of use when assessing the toxic properties not only of existing materials but also of future materials containing components that have already undergone toxicological analysis. Each entry gives a brief description of the material and its uses followed by summaries of studies on its toxicity. Extensive references are included for those requiring further details on the tests and results. The handbook is intended as a reference work and will provide a valuable reference work for all those involved with health and safety in the rubber and plastics industries. "This publication is a translation of a Russian text. As a consequence, the polymers and additives are not strictly in English alphabetical order."
Morris Hepatomas
In 1960, Dr. Van R. Potter and Dr. Henry Pitot (at McCardle Laboratory in Madison, Wisconsin), Dr. Tetsuo Ono (then at McCardle Laboratory and now at the Japanese Foundation for Cancer Research in Tokyo, Japan) and Dr. Harold P. Morris (then at the National Cancer Institute and now at Howard University, Washington, D. C. ) decided that an experimental cancer model would be an invaluable tool to examine neoplastic changes in cells. Since they were study ing the various highly specific metabolic processes which are unique to liver tissues, they determined that a transplantable liver cancer model would be the ideal system to work with. This system would provide for comparison of normal liver ti...
Chlorinated Solvents
Environmental forensics is emerging and evolving into a recognized scientific discipline with numerous applications, especially regarding chlorinated solvents. This unique book provides the reader with a concise compilation of information regarding the use of environmental forensic techniques for age dating and identification of the source of a chlorinated solvent release. Concentrating on the five commonly encountered chlorinated solvents (perchloroethylene, trichloroethylene, methyl chloroform, carbon tetrachloride and CFC-113), forensic opportunities applicable to each are presented including the use of stabilizers, manufacturing impurities, surrogate chemicals and physical measurements and degradation products as diagnostic indicators. Detailed historical chronology of the applications of the solvents and specific chapters devoted to dry cleaning and vapor degreasing equipment are included as are generic forensic approaches. Forming a basis for further ideas in the evolution of environmental forensic techniques, Chlorinated Solvents will be an indispensable reference tool for researchers, regulators and analysts in the field.
