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Paraneoplastic syndromes comprise a variety of signs and symptoms that are not directly caused by the primary tumor or its metastases. They may be metabolic, dystrophic or degenerative disorders resulting from remote humoral or hormonal effects, and spontaneously disappear after successful tumor excision or chemo- or radiotherapy. A few years ago, paraneoplastic syndromes were still thought to be rare. Today, we know that a single tumor is capable of producing a variety of hormones and that paraneoplastic syndromes are caused by this ectopic formation of hormones, hormone-like polypeptides, and growth factors. Recent research has shown that viral metabolic intermediates, mutated oncogenes, a...
Complete remissions and survival times of tumor patients are increasing steadily - and so is the risk of developing therapy-associated secondary malignancy. At the same time, we face the growing diagnostic and therapeutic problem of tumorigenesis during posttransplantation immunosuppressive therapy. The theoretical section delves into the various causes of tumorigenesis, with special chapters on secondary chemo- and/or radiotherapy-induced tumorigenesis and neoplasia occurring during posttransplantation immunosuppressive therapy. The risk of individual cytostatic agents causing secondary malignoma is covered, as are the functions and dysfunctions of immunosurveillance. The immune system’s ...
Informs scientists and health care professionals about all the medically relevant aspects of this rapidly evolving field. • Covers novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention. • Addresses infections and syndromes related to particular organ systems, as well as the fundamentals of modern medical virology. • Includes crucial information on immune responses and vaccinology, diagnostics, antivirals, and the nascent field of gene therapy. • Provides agent-specific chapters that detail the virology, epidemiology, pathogenesis, clinical manifestations, and prevention and treatment of important viral pathogens.
This handbook details advances in pancreatic cancer research that have a profound and lasting impact on the field. It features the work of authors who are the very best in their respective fields and will have widespread appeal among clinicians, pathologists and basic scientists who are now struggling to understand this complex and rapidly expanding field.
Der "Schmoll" bestätigt mit dieser nunmehr 4. Auflage weiterhin seinen Ruf als Standardwerk der Internistischen Onkologie. Er gilt nicht nur als das umfangreichste sondern auch als das profundeste Nachschlagewerk, das zuverlässig und nahezu vollständig über den neuesten Wissensstand in der Onkologie informiert. Durch eine noch übersichtlichere Gliederung und ein neues Layout handelt es sich hier um ein äußerst instruktives Lehrbuch, das für den onkologisch tätigen Arzt eine sehr wertvolle Informationsquelle darstellt und zur Basisausstattung in jede onkologische Abteilung gehören sollte. Band 1 stellt Grundlagen, Richtlinien, Antineoplastische Substanzen, Toxizitäten, prophylaktis...
Comprehensive and fully up to date, the six-volume Plastic Surgery remains the gold standard text in this complex area of surgery. Completely revised to meet the demands of both the trainee and experienced surgeon, Principles, Volume 1 of Plastic Surgery, 5th Edition, features new, full-color clinical photos, procedural videos, lectures, and authoritative coverage of hot topics in the field. Editor-narrated video presentations offer a step-by-step audio-visual walkthrough of techniques and procedures. - New chapters cover value-based healthcare, health services research in plastic surgery, education and teaching in plastic surgery, and gender-affirming surgery; coverage throughout includes n...
Comprehensive and fully up to date, Dr. Peter Neligan's six-volume masterwork, Plastic Surgery, 5th Edition, remains the gold standard text in this complex area of surgery. Completely revised to meet the demands of both the trainee and experienced surgeon, it features new, full-color clinical photos, procedural videos, and lectures across all six volumes. Bonus material online includes additional text, images, and over 200 procedural videos that help you improve your mastery of the latest techniques. - Easily find the answers you need with an organization that features separate volumes covering Principles • Aesthetic • Craniofacial, Head and Neck Surgery and Pediatric Plastic Surgery •...