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Next Generation Sequencing Based Clinical Molecular Diagnosis of Human Genetic Disorders
  • Language: en
  • Pages: 366

Next Generation Sequencing Based Clinical Molecular Diagnosis of Human Genetic Disorders

  • Type: Book
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  • Published: 2017-05-15
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  • Publisher: Springer

Next Generation Sequencing technology has been applied to clinical diagnoses in the past three to five years using various approaches, including target gene panels and whole exomes. The purpose of this book is to summarize the experiences, the results, advantages and disadvantages, along with future development in the area of NGS-based molecular diagnosis. This up-to-date volume will not only provide the readers working with Next Generation Sequencing the basics on how to apply the technology to molecular diagnosis, but will present the results and experience of practical application.

Hematology
  • Language: en
  • Pages: 2696

Hematology

Get the expert guidance you need to offer your patients the best possible outcomes with Hematology: Basic Principles and Practice, 7th Edition. This thoroughly up-to-date text contains both unparalleled scientific content and must-know clinical guidance, so you can enhance your problem-solving skills and make optimal use of the newest diagnostic techniques and therapeutic options in this fast-changing field. Delivers state-of-the-art information and guidance from editors and global contributors who are at the forefront of their respective subspecialty areas Features sweeping content updates throughout, including basic science research which serves as a foundation for modern hematology, recen...

Plants and Phytomolecules for Immunomodulation
  • Language: en
  • Pages: 547

Plants and Phytomolecules for Immunomodulation

This book describes the process of immunomodulation and the plants which possess immunomodulation properties to boost the immune system. The immunomodulation process is highly relevant to address emerging as well as existing diseases in humans. A better immune system triggers the cellular responses for neutralizing and combating the onset of disease conditions. Chapters in the book discuss plants that have profound effects on the health and well-being of humans. They discuss the natural phytochemicals that have immense diversity and uniqueness of molecules. Molecules belonging to phenylpropanoids, terpenoids, steroids, alkaloids, and tannins etc possess a variety of pharmacological activities. The chapters describe how bioactive exert effects even when taken as part of the diet, supplement, and or as traditional herbal medicine. This book provides up-to-date scientific knowledge about the activities and mechanisms and leads in the area of medicinal plants and phytochemicals with immunomodulation properties. This book is meant for students, academics, researchers, and industry professionals interested in pharmacology, immunology, and plant secondary metabolites.

Mental retardation
  • Language: en
  • Pages: 240

Mental retardation

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Prognosis of Neurological Diseases
  • Language: en
  • Pages: 514

Prognosis of Neurological Diseases

  • Type: Book
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  • Published: 2015-11-19
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  • Publisher: Springer

This book offers clear, detailed guidance on all aspects of prognostic evaluation in patients who have been involved in a serious accident with neurological consequences or have been diagnosed with a severe neurological illness. It covers the full range of disorders of the central and the peripheral nervous system, not only providing very accurate prognostic estimates but also addressing relevant clinical issues, differential diagnosis, and the role of imaging. The book is practically oriented and designed for use on a daily basis when assessing prognosis and discussing the outcome with patients, their families, and other interested parties. It will support patient–doctor partnerships by ensuring that the most professional answers can be given to patients' and doctors' questions and by promoting realistic expectations of the effect of medical interventions. In addition, it will enable doctors, lawyers, and other professionals to understand relevant issues when an estimate of prognosis and life expectancy is the subject of legal dispute.

Heart Development and Regeneration
  • Language: en
  • Pages: 1126

Heart Development and Regeneration

The development of the cardiovascular system is a rapidly advancing area in biomedical research, now coupled with the burgeoning field of cardiac regenerative medicine. A lucid understanding of these fields is paramount to reducing human cardiovascular diseases of both fetal and adult origin. Significant progress can now be made through a comprehensive investigation of embryonic development and its genetic control circuitry. Heart Development and Regeneration, written by experts in the field, provides essential information on topics ranging from the evolution and lineage origins of the developing cardiovascular system to cardiac regenerative medicine. A reference for clinicians, medical rese...

Lesser Flamingos
  • Language: en
  • Pages: 249

Lesser Flamingos

  • Type: Book
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  • Published: 2018-12-31
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  • Publisher: Springer

This book provides insights into the fascinating life of the Lesser Flamingo (Phoeniconaias minor) and describes how this enigmatic bird has adapted to the extreme conditions of tropical soda lakes and can even withstand the caustic effects of brine. However, humans are increasingly disrupting the natural cycles of these wetlands, and for these pink birds characteristic of these salt lakes, it is becoming more and more difficult to find suitable habitats, food and breeding grounds. Their fate is considered a cautionary example of man’s dealings with nature. Will the Lesser Flamingo survive in a man-made world? Flamingos are considered to be an embodiment of the Phoenix, and the author interweaves his personal experiences with and observations of the flamingos’ unusual habitats with the Phoenix motif in order to stimulate reflection on the circle of life. Written in an accessible style that combines science, biological information and the author’s own travels and fieldwork, the book also includes a wealth of captivating images. As such, it offers a unique resource for biologists and nature-loving Africa and Asia enthusiasts alike.

The Gene, the Clinic, and the Family
  • Language: en
  • Pages: 404

The Gene, the Clinic, and the Family

  • Type: Book
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  • Published: 2013-07-04
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  • Publisher: Routledge

While some theorists argue that medicine is caught in a relentless process of ‘geneticization’ and others offer a thesis of biomedicalization, there is still little research that explores how these effects are accomplished in practice. Joanna Latimer, whose groundbreaking ethnography on acute medicine gave us the social science classic The Conduct of Care, moves her focus from the bedside to the clinic in this in-depth study of genetic medicine. Against current thinking that proselytises the rise of laboratory science, Professor Latimer shows how the genetic clinic is at the heart of the revolution in the new genetics. Tracing how work on the abnormal in an embryonic genetic science, dys...

Children with Complex Medical Issues in Schools
  • Language: en
  • Pages: 545

Children with Complex Medical Issues in Schools

Increasingly, children with significant medical issues are being incorporated into the general school environment. Given the potential effects of various disorders and conditions on educational prognosis, it is important for neuropsychologists, pediatric psychologists, school psychologists, teachers, and other professionals who are working with these children to be aware of the nature and course of these many disorders as well as the avenues for rehabilitation, accommodation, and classroom modification. In Children with Complex Medical Issues in Schools, Dr. Castillo bridges the gap between research and practice and provides a concise, yet thorough reference that covers a broad range of cond...

Noonan Syndrome and Related Disorders
  • Language: en
  • Pages: 178

Noonan Syndrome and Related Disorders

In this book, internationally recognized experts review the most important advances regarding the group of human developmental disorders caused by constitutive dysregulation of the Ras-MAPK signalling pathway, including Noonan, cardiofaciocutaneous, LEOPARD and Costello syndromes. A historical overview given by Jacqueline Noonan is followed by chapters dedicated to comprehensive clinical summaries of each condition and up-to-date reviews on associated gene mutations and molecular pathomechanisms. Genotypephenotype correlations are outlined. Further topics include the characterization and underlying mechanisms of common abnormalities in these syndromes such as growth failure, heart defects, a...