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Sherrington's Loom
How does the brain create consciousness? How is it that we have a sense of self; a self that can identify thousands of people, places, objects, words, and musical melodies? While the ultimate challenge--that of transforming electrical impulses in nerve cells into sensations, thoughts, and actions--remains a mystery, there is a great deal that is now known about the way the brain functions. Further, that knowledge is increasing through the use of ever more powerful experimental methods. Sherrington's Loom brings the key information together by blending crucial historical discoveries with more recent findings in the laboratory and neurological clinic. This book is a "must-have" for anyone interested in the history of medicine and science, and who is eager for insights as to how the conscious brain may work.
Sherrington
So much has been written about the scientific contributions of Sherrington that the man himself, and his thoughts, have been overshadowed. More and more, students of history are calling for creative writing on the whole man, particularly when he is a genius. Those interested in the genesis of ideas want to know the settings for discoveries and the relevant circumstances which ushered in new truths and new insights. The "prepared mind" which Pasteur saw as the only one to be "favoured by fortune" is of immense importance in science, and our account of Sherring ton, we hope, will fill a very real gap in this field. During his life Sherrington actively discouraged any sugges tions that a biography be written. For that reason it was not until 1947 that there were any biographical notes by John Fulton, Graham Brown and A. D. Ritchie in a number of the British Medical Journal commemorating his ninetieth birthday, and in addition there was a leading article entitled "The Influence of Sherrington on Oinical Neurology". He left no autobiographical material except the few pages of reminiscences entitled "Mar ginalia", an essay written in honour of Charles Singer (1953).
Minds Behind the Brain
Traces the study of the brain from the ancient Egyptians, through the classical world of Hippocrates, the time of Descartes, and the era of Broca, to modern researchers such as Sperry, and examines their sources and tools.
The Sherrington-Kirkpatrick Model
The celebrated Parisi solution of the Sherrington-Kirkpatrick model for spin glasses is one of the most important achievements in the field of disordered systems. Over the last three decades, through the efforts of theoretical physicists and mathematicians, the essential aspects of the Parisi solution were clarified and proved mathematically. The core ideas of the theory that emerged are the subject of this book, including the recent solution of the Parisi ultrametricity conjecture and a conceptually simple proof of the Parisi formula for the free energy. The treatment is self-contained and should be accessible to graduate students with a background in probability theory, with no prior knowledge of spin glasses. The methods involved in the analysis of the Sherrington-Kirkpatrick model also serve as a good illustration of such classical topics in probability as the Gaussian interpolation and concentration of measure, Poisson processes, and representation results for exchangeable arrays.
Minds behind the Brain : A History of the Pioneers and Their Discoveries
Attractively illustrated with over a hundred halftones and drawings, this volume presents a series of vibrant profiles that trace the evolution of our knowledge about the brain. Beginning almost 5000 years ago, with the ancient Egyptian study of "the marrow of the skull," Stanley Finger takes us on a fascinating journey from the classical world of Hippocrates, to the time of Descartes and the era of Broca and Ramon y Cajal, to modern researchers such as Sperry. Here is a truly remarkable cast of characters. We meet Galen, a man of titanic ego and abrasive disposition, whose teachings dominated medicine for a thousand years; Vesalius, a contemporary of Copernicus, who pushed our understanding...
Reactive and Functional Polymers Research Advances
Presents research on inorganic and organic functional polymers, both solid and liquid, acting as reagents, catalysts, carriers of protecting groups, templates, ion-exchangers, selective sorbents, chelating agents, supports for enzymes and cells, and the like. This book also covers reactive crosslinkable prepolymers, and degradable polymers.
Falls in Older People
Since the first edition of this very successful book was written to synthesise and review the enormous body of work covering falls in older people, there has been an even greater wealth of informative and promising studies designed to increase our understanding of risk factors and prevention strategies. This second edition, first published in 2007, is written in three parts: epidemiology, strategies for prevention, and future research directions. New material includes recent studies covering: balance studies using tripping, slipping and stepping paradigms; sensitivity and depth perception visual risk factors; neurophysiological research on automatic or reflex balance activities; and the roles of syncope, vitamin D, cataract surgery, health and safety education, and exercise programs. This edition will be an invaluable update for clinicians, physiotherapists, occupational therapists, nurses, researchers, and all those working in community, hospital and residential or rehabilitation aged care settings.
Molecular Biology in Cellular Pathology
"Molecular Biology in Cellular Pathology" - Jetzt erscheint dieser erfolgreiche Klassiker in der 2. aktualisierten Auflage. Der Band beschreibt die wichtigsten Fortschritte in der Zell- und Molekularbiologie. In den letzten Jahren haben neue Erkenntnisse über den molekularen Aufbau der Zelle zur Entwicklung neuer, leistungsstarker Analysetechniken geführt, die eine größere Genauigkeit bei der Diagnose, Prognose und Behandlung von Krankheiten sowie bei der Untersuchung pathologischer Stadien ermöglichen. Insbesondere werden neue Verfahren diskutiert, die fluoreszierende Farbstoffe, DNA Microarrays, Proteinchemie und Massenspektrometrie einsetzen. Darüber hinaus enthält das Buch Informationen zum Human-Genom-Projekt und zu den neuen Disziplinen der Genomik und Proteomik, soweit diese für die Pathologie relevant sind. Neu an dieser 2. Auflage sind die Farbtafeln, die die enormen Fortschritte in der Fluoreszenz-Markierung von Zellmaterial anschaulich belegen.
Galvani's Spark
Galvani's Spark describes the gradual understanding of the nerve impulse. Proceeding from a chance observation on a frog leg, to studies on squid giant axons and bacteria, this book concludes with the increasing realization that ion channells are responsible for a variety of clinical disorders.
