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Bioinformatics Research and Applications
This book constitutes the refereed proceedings of the 19th International Symposium on Bioinformatics Research and Applications, ISBRA 2023, held in Wrocław, Poland, during October 9–12, 2023. The 28 full papers and 16 short papers included in this book were carefully reviewed and selected from 89 submissions. They were organized in topical sections as follows: reconciling inconsistent molecular structures from biochemical databases; radiology report generation via visual recalibration and context gating-aware; sequence-based nanobody-antigen binding prediction; and hist2Vec: kernel-based embeddings for biological sequence classification.
Network Bioscience, 2nd Edition
Network science has accelerated a deep and successful trend in research that influences a range of disciplines like mathematics, graph theory, physics, statistics, data science and computer science (just to name a few) and adapts the relevant techniques and insights to address relevant but disparate social, biological, technological questions. We are now in an era of 'big biological data' supported by cost-effective high-throughput genomic, transcriptomic, proteomic, metabolomic data collection techniques that allow one to take snapshots of the cells' molecular profiles in a systematic fashion. Moreover recently, also phenotypic data, data on diseases, symptoms, patients, etc. are being coll...
Advancements in Biomass Recalcitrance: The Use of Lignin for the Production of Fuels and Chemicals
Lignocellulosic biomass has great potentials as an alternative feedstock for fuels and chemicals. For effective utilization of biomass, biomass recalcitrance, which is inherent resistance of plant cell walls to biological deconstruction, needs to be reduced. Among many factors in biomass, lignin is significantly related to biomass recalcitrance. Lignin, a complex aromatic polymer, is the largest non-carbohydrate component (15-40% dry weight) in most terrestrial plants. In nature, it provides a structural integrity, facilitates water and nutrient transport, and protects plants from microbial attack. From a different angle, lignin significantly contributes to biomass recalcitrance, so it is ne...
Immersive Analytics
Immersive Analytics is a new research initiative that aims to remove barriers between people, their data and the tools they use for analysis and decision making. Here the aims of immersive analytics research are clarified, its opportunities and historical context, as well as providing a broad research agenda for the field. In addition, it is reviewed how the term immersion has been used to refer to both technological and psychological immersion, both of which are central to immersive analytics research.
Spectral Graph Theory
This text discusses spectral graph theory.
Spectra of Graphs
This book gives an elementary treatment of the basic material about graph spectra, both for ordinary, and Laplace and Seidel spectra. The text progresses systematically, by covering standard topics before presenting some new material on trees, strongly regular graphs, two-graphs, association schemes, p-ranks of configurations and similar topics. Exercises at the end of each chapter provide practice and vary from easy yet interesting applications of the treated theory, to little excursions into related topics. Tables, references at the end of the book, an author and subject index enrich the text. Spectra of Graphs is written for researchers, teachers and graduate students interested in graph spectra. The reader is assumed to be familiar with basic linear algebra and eigenvalues, although some more advanced topics in linear algebra, like the Perron-Frobenius theorem and eigenvalue interlacing are included.
Advanced Design of Mechanical Systems: From Analysis to Optimization
Multibody systems are used extensively in the investigation of mechanical systems including structural and non-structural applications. It can be argued that among all the areas in solid mechanics the methodologies and applications associated to multibody dynamics are those that provide an ideal framework to aggregate d- ferent disciplines. This idea is clearly reflected, e. g. , in the multidisciplinary applications in biomechanics that use multibody dynamics to describe the motion of the biological entities, in finite elements where multibody dynamics provides - werful tools to describe large motion and kinematic restrictions between system components, in system control where the methodolo...
Understanding Complex Biological Systems with Mathematics
This volume examines a variety of biological and medical problems using mathematical models to understand complex system dynamics. Featured topics include autism spectrum disorder, ectoparasites and allogrooming, argasid ticks dynamics, super-fast nematocyst firing, cancer-immune population dynamics, and the spread of disease through populations. Applications are investigated with mathematical models using a variety of techniques in ordinary and partial differential equations, difference equations, Markov-chain models, Monte-Carlo simulations, network theory, image analysis, and immersed boundary method. Each article offers a thorough explanation of the methodologies used and numerous tables...
