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Handbook of Atypical Parkinsonism
Improved diagnostic sophistication is increasingly enabling neurologists to differentiate between Parkinson's disease and other atypical parkinsonism (AP), such as multiple system atrophy, progressive supranuclear palsy, corticobasal degeneration, and dementia with Lewy bodies. The Handbook of Atypical Parkinsonism is a comprehensive survey of all diseases of this category, providing an authoritative guide to the recognition, diagnosis and management of these disorders. Each chapter follows a common structure, commencing with the full basic science of the disorder under consideration, followed by descriptions of the clinical picture and differential diagnosis. Subsequent chapters discuss current and future therapeutic approaches to these difficult conditions. Written and edited by leading practitioners in the field, clinicians in neurology and other specialties will find this book essential to the understanding and diagnosis of this complex group of disorders.
Handbook of Neurological Therapy
This is a practical book on neurological therapy. It is aimed at giving concise and updated answers to busy practicing clinicians in the clinic, ward, or emergency department. An evidence-based approach is used, but when there is no evidence or the data are inconclusive, an expert opinion is always given in order to meet the expectations of the reader. All neurological conditions, common and less common, are discussed; each chapter has a similar format, and contains an initial brief introduction on the epidemiology and clinical features of each disease. The therapy is then discussed, including pharmacological and non-pharmacological, with wide use of Tables & Figures. Flowcharts are also included in most of the chapters.
Decision Algorithms for Emergency Neurology
This book adopts a novel approach: procedures: instead of discussing the diagnostic categories of neurological syndromes, it focuses on the symptoms of common neurological presentations (especially in the emergency room or on the ward), and the diagnostic hypotheses that can be validated or rejected case by case as a result. Each chapter covers one of the main symptoms of emergencies in neurology – from transient consciousness disturbances to focal deficits, acute muscular disorders, respiratory insufficiency in neurological disorders, headaches, delirium, seizures and epileptic status, para-and tetraplegia, and head trauma, to acute functional disorders – and includes tables and figures...
Movement Disorders
The use of animal models is a key aspect of scientific research in numerous fields of medicine. Movement Disorders, Second Edition vigorously examines the important contributions and application of animal models to the understanding of human movement disorders, and serves as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. The book is divided into sections on Parkinson's disease, Huntington's disease, dystonia, tremor,...
Pathophysiology, Pharmacology and Biochemistry of Dyskinesia
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Dystonia and Dystonic Syndromes
The current concept of dystonic movement connects the abnormal function of somatosensory pathways and somatosensory analyzers with the dystonic performance of motor action, which is based on the abnormality of sensorimotor integration. This concept is reflected not only in idiopathic dystonia, but also in secondary and symptomatic dystonias. This book will give a comprehensive account of the history of the terms dystonia and dystonic, the physiology of dystonic movement and the genetics and clinical appearance of primary and secondary dystonias. Taking into consideration latest research findings, Dystonia and Dystonic Syndromes offers an in-depth discussion of current treatment options available for dystonia, including pharmacotherapy, surgery and neurorehabilitation. Therefore, it serves as a valuable reference for practitioners in the fields of neurology, neurosurgery, psychiatry and neuroradiology as well as for neuroscientists.
Levodopa-Induced Dyskinesia in Parkinson's Disease
This book aims to provide a single reference source on levodopa-induced dyskinesias (LID) from ‘bench to bedside’. Initial chapters review the clinical features and phenomenology of LID with video examples; epidemiology and genetic risk factors for LID are covered as a background to understanding risk factors for developing LID. The following chapters cover the latest preclinical studies aiming to understand the pathophysiology of LID at the cellular, neurochemical, neurophysiological and circuitry level with detailed discussion of mechanisms and future directions to take the field forward; clinical studies from phase II to phase IV; on going RCTs in LID and evidence-based medicine reviews of treatment options. Levodopa-Induced Dyskinesia in Parkinson’s Disease is aimed at an international audience of movement disorder neurologists; neuroscientists; trainees and graduate and post-graduate students.
Parkinson Disease,An Issue of Clinics in Geriatric Medicine E-Book
This issue of Clinics in Geriatric Medicine, guest edited by Drs. Carlos Singer and Stephen G. Reich, is devoted to Parkinson Disease. Articles in this issue include: Parkinson Disease: An overview of epidemiology, pathology, genetics and pathophysiology; Diagnosis and Differential Diagnosis of Parkinson Disease; Tremor in the Elderly: Is it Parkinson Disease?; Management of Early Parkinson Disease; Management of Advanced Parkinson Disease; Orthostatic Hypotension in Parkinson Disease; Management of Urological and Sexual Dysfunction in Parkinson Disease; Gastrointestinal Care of the Parkinson Patient; Cognitive Impairment and Dementia in Parkinson Disease; Depression and Anxiety in Parkinson Disease; Hallucinations, Delusions, and Impulse Control Disorders in Parkinson Disease; Sleep Disorders in Parkinson Disease; Orthopedic Care of the Parkinson Patient; Driving in Parkinson Disease; Palliative Care in Parkinson Disease; Multidisciplinary Care of Parkinson Disease: Fall prevention, fatigue, exercise, rehabilitative therapies, caregiver strain; and Hospitalization of the Patient with Parkinson Disease.
Rating Scales in Parkinson's Disease
For many years, the need to develop valid tools to evaluate signs and symptoms of Parkinson Disease (PD) has been present. However the understanding of all intricacies of rating scales development was not widely available and the first attempts were relatively crude. In 2002, the Movement Disorders Society created a task force to systemize the measurement of Parkinson's Disease. Since then, the Task Force has produced and published several critiques to the available rating scales addressing both motor and non-motor domains of Parkinson Disease. Additionally the task force initiated a project to develop a new version of the UPDRS, the MDS-UPDRS. But none of this was made available in one conv...
Movement Disorders
Clinical case studies have long been recognized as a useful adjunct to problem-based learning and continuing professional development. This book collects over 90 of the most memorable and challenging movement disorder cases from the world's leading authorities in this specialty. Compelling vignettes covering the entire phenomenology of movement disorders are presented succinctly but descriptively to walk the reader through the diagnostic process-much like being in the examining room with a master clinician. Each case follows a set format consisting of four sections: The Case; The Approach; The Lesson; Reference and Suggested Readings. Imaging findings and other illustrations amplify the discussion where pertinent.
