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Movement Disorders
The use of animal models is a key aspect of scientific research in numerous fields of medicine. Movement Disorders, Second Edition vigorously examines the important contributions and application of animal models to the understanding of human movement disorders, and serves as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. The book is divided into sections on Parkinson's disease, Huntington's disease, dystonia, tremor,...
The development of deep brain stimulation for neurological and psychiatric disorders: clinical, societal and ethical issues
To date more than eighty thousand patients worldwide have received deep brain stimulation (DBS), mainly in order to alleviate symptoms of treatment-resistant disorders such as tremor associated with Parkinson’s disease, essential tremor, chronic pain, epilepsy, obsessive compulsive disorder, major depression and Tourette syndrome. The number of indications for neurological and psychiatric conditions using this technology is rapidly increasing, raising important societal and ethical issues that cannot be dealt with by scientists and clinicians on their own, but need discussions among all possible stakeholders on questions such as: what are the comprehensive risks and benefits of this techno...
Manual of Botulinum Toxin Therapy
Providing practical, visually oriented guidance on the benefits of botulinum toxin in a wide variety of disorders, some new and unexpected, this new edition of Manual of Botulinum Toxin Therapy is fully updated in scope and detail. Chapters discuss the pathophysiology of each condition, summarizing the rationale for botulinum toxin, and describing the injection approach. Clear illustrations of the injection sites are included, using a 'clinician's eye' perspective, which allows physicians to readily identify anatomical landmarks and approach angles for injection. Dosing tables for available toxin formulations are included. The Manual covers cosmetic treatment of the upper and lower face, as well as aesthetic smile correction. Extensive guidance on how to use ultrasound and how cadaveric dissections can assist localization and targeting of injections is provided. Designed for teaching and bedside guidance, the Manual is useful to a diverse range of clinicians looking to use botulinum toxin in their practice.
Pathophysiology, Pharmacology and Biochemistry of Dyskinesia
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Decision Algorithms for Emergency Neurology
This book adopts a novel approach: procedures: instead of discussing the diagnostic categories of neurological syndromes, it focuses on the symptoms of common neurological presentations (especially in the emergency room or on the ward), and the diagnostic hypotheses that can be validated or rejected case by case as a result. Each chapter covers one of the main symptoms of emergencies in neurology – from transient consciousness disturbances to focal deficits, acute muscular disorders, respiratory insufficiency in neurological disorders, headaches, delirium, seizures and epileptic status, para-and tetraplegia, and head trauma, to acute functional disorders – and includes tables and figures...
High-Tech Personalized Healthcare in Movement Disorders
The management of movement disorders is undergoing rapid transformation through the use of innovative health technologies, such as wearable sensors, mobile apps, robotics, and telemedicine systems. These technologies continue to evolve, providing new solutions for early diagnosis, remote monitoring, tailored treatments, and enhanced rehabilitative strategies that cater to individual needs through personalized approaches. With the aid of new health technologies, motor abnormalities can be sensitively recognized and objectively assessed, providing quantifiable measures to detect subtle changes associated with treatment response and disease progression. Moreover, long-term instrumental monitoring offers the opportunity for improving therapeutic strategies by gathering ecological data directly at patients’ homes in free-living situations.
Biomarkers of Neurological and Psychiatric Disease
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Axon Growth and Regeneration: Part 1
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding Axon Growth and Regeneration. - Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Neurobiology of Acupuncture
This book summarises the recent development in acupuncture research and in particular, the neurobiology of acupuncture. It provides a focus but a diverse range of subjects covering many body systems. The first a few chapters discuss the basic principles of acupuncture, then its modulatory effects on nervous system such as induction of neurotrophin and neurogenesis in the brain. Late chapters explore the clinical effects and potential mechanisms of acupuncture on different conditions ranging from neurological diseases such as Parkinson's, Alzheimer's, and stroke, to psychiatric illnesses, insomnia, hypertension, gastrointestinal diseases and drug addiction. We believe this will promote the understanding acupuncture treatment and enhance acupuncture research in the future. - This volume of International Review of Neurobiology brings together cutting-edge research on the neurobiology of acupuncture - It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery
Rating Scales in Parkinson's Disease
For many years, the need to develop valid tools to evaluate signs and symptoms of Parkinson Disease (PD) has been present. However the understanding of all intricacies of rating scales development was not widely available and the first attempts were relatively crude. In 2002, the Movement Disorders Society created a task force to systemize the measurement of Parkinson's Disease. Since then, the Task Force has produced and published several critiques to the available rating scales addressing both motor and non-motor domains of Parkinson Disease. Additionally the task force initiated a project to develop a new version of the UPDRS, the MDS-UPDRS. But none of this was made available in one conv...
