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The supply chain is at the heart of every successful business organization's decision-making process. This textbook explains how to create a winning supply chain management strategy by spotlighting how senior executives in European and US companies have turned their supply chains into strategic weapons designed to convert threats, risks and outside pressures into competitive advantages. Strategic Supply Chain Management contains twenty real-world cases, all of which have been field researched by a top author team and tested out in the classroom. Each case adopts an executive leadership perspective to illuminate the real dilemmas faced by managers. The authors draw on their extensive classroom and industry experience to ensure that the writing style is geared towards an executive education readership. This elite case package will provide a complete teaching resource and authentic learning experience for MBA and executive education classes in Supply Chain Management throughout the world.
International business is undergoing continuous transformation as multinational firms and comparative management evolve in the changing global economy. To succeed in this challenging environment, firms need a well-developed capability for sound strategic decisions. This comprehensive work provides an applied and integrated strategic framework for developing capabilities that lead to global success. It is designed to help readers achieve three essential objectives. First, it provides intellectual and practical guidelines for readers to execute goals and strategies that lead to meaningful and productive results. The book is packed with frameworks, cases, anchoring exercises, techniques, and to...
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ADVANCES IN CANCER RESEARCH is a biannual publication that includes timely reviews on the most cutting-edge issues in cancer research. Volume 66 contains encompassing overviews of p53 and its role in both breast cancer and in the cell cycle. Approximately 50% of all human tumors involve mutations of the p53 gene, suggesting that proper understanding of its properties and mechanisms could offer real hope for finding successful clinical therapy. Other themes presented in Volume 66 include cyclins and cyclin-dependent kinases in the cell cycle. Approximately 50% of all human tumors involve mutations of the p53 gene, suggesting that proper understanding of its properties and mechanisms could off...
The ability of neoplastic cells to survive exposure to various chemotherapeutic drugs represents the main obstacle to successful cancer chemotherapy. This book deals with a particular type of resistance in tumor cells that represents a single but especially important aspect of the multifaceted problem of cancer drug resistance. This type of resistance, known as multidrug or pleiotropic drug resistance, is characterized by cross-resistance of cells to several different classes of cytotoxic drugs, including some of the most commonly used anticancer agents. Over the last several years, there has been a veritable explosion of genetic, biochemical, and clinical information on multidrug resistance...
This book delivers new IMD insights on an emerging challenge - how to deal with overwhelming complexity. Global organizations face a complex decision-making environment. On one side, diversity of cultures, customers, competitors and regulations creates complexity; on the other, competitive pressures cause expanding countries to extract more synergies across products and regions. In such a climate, a new way of thinking, acting and organizing is needed beyond the familiar ‘control’ mindset. Drawing together insights from across the expert faculty, Managing Complexity in the Global Organization presents IMD’s framework on how to understand complexity and its four key drivers (diversity; interdependence; ambiguity and flux), along with solutions on specific issues in a variety of functions, industries and markets. The focus is on providing practical solutions based on real-life examples.
100 Questions & Answers About Coronaviruses is a timely resource that organizes and distills cutting-edge information and data on COVID-19 in a single, convenient, easy-to-read resource. Featuring a foreword by Dr. Aaron Glatt, Chairman and Chief of Infectious Diseases and Hospital Epidemiologist at Mount Sinai South Nassau, 100 Questions and Answers About Coronaviruses begins with a history and myths about coronaviruses and progresses to answer questions about how COVID-19 affects children and adults, current vaccine research, quarantine, social distancing, preventing future pandemics, and more often asked questions. 100 Questions & Answers About Coronaviruses is an invaluable resource for every nursing or public health student and a must-read for anyone interested in learning about the virus that is reshaping our daily lives.
In the second edition of their critically acclaimed book, Ronald Bukowski, Robert Motzer, and Robert Figlin have thoroughly updated and expanded their survey of clinical, biological and pathological management of localized and advanced renal cell carcinoma. A panel of internationally renowned contributors explores the latest developments in molecular genetics, focusing on the novel targets that have been discovered in epithelial renal tumors. The discussion includes the specific biology of selected target molecules or receptors and the various agents that inhibit these targets, including full chapters devoted to drugs that selectively inhibit receptor tyrosine kinases, such as sunitinib and axitinib. Further attention is paid to leading-edge strategies that target and inhibit tumor associated angiogenesis and block the vascular endothelial growth factor pathway. Comprehensive and authoritative, Renal Cell Carcinoma: Molecular Targets and Clinical Applications, Second Edition is the definitive text on the rapidly evolving landscape of experimental therapeutics, written and edited by the pioneers of the field.
This book is about giving the CEO what he wants to know about Value creation and success.